scholarly journals Failed Back Surgery Syndrome: Magnetic Resonance Imaging Assessment

2014 ◽  
Vol 11 (1) ◽  
pp. 11-17
Author(s):  
Esam Hemat ◽  
Amr El-Adawy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Failed Back Surgery Syndrome ◽  
Resonance Imaging ◽  
Failed Back Surgery ◽  
Back Surgery ◽  
Magnetic Resonance Imaging Assessment

scholarly journals Celecoxib-Loaded Electrospun Fibrous Antiadhesion Membranes Reduce COX-2/PGE2 Induced Inflammation and Epidural Fibrosis in a Rat Failed Back Surgery Syndrome Model

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Wei Wang ◽  
Yunhao Wang ◽  
Tengfei Lou ◽  
Mingqian Ding ◽  
Juehong Li ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Surgery ◽  
Failed Back Surgery Syndrome ◽  
Surgical Trauma ◽  
Epidural Fibrosis ◽  
Resonance Imaging ◽  
Failed Back Surgery ◽  
Back Surgery ◽  
Cox 2 ◽  
Fibrous Membranes

To date, failed back surgery syndrome (FBSS) remains a therapy-refractory clinical condition after spinal surgery. The antiadhesion membrane is applied to prevent FBSS by isolating fibrosis; however, the inflammation stimulated by the foreign body and surgical trauma needs to be further resolved simultaneously. Therefore, we developed new electrospun polycaprolactone (PCL) fibrous membranes loaded with celecoxib (CEL) to prevent fibrosis and inflammation associated with FBSS. The CEL-loaded PCL fibers were randomly distributed, and the drug was released over two weeks. Fluorescence micrographs revealed that the fibroblasts proliferated less on the PCL-CEL fibrous membranes than in the PCL group and the blank control. In the rat laminectomy model after 4 weeks, magnetic resonance imaging of epidural fibrosis was least in the PCL-CEL group. Expression of COX-2 and PGE2 was lower in the PCL-CEL group. It concluded that the CEL-loaded PCL membrane could reduce fibrosis and inflammation in a rat model of FBSS via COX-2/PGE2 signaling pathways.

scholarly journals Ultrasonographic evaluation of meniscal extrusion: comparison with magnetic resonance imaging assessment

2013 ◽  
Vol 21 ◽  
pp. S185 ◽  
Author(s):  
M.D. Crema ◽  
E. Gregio-Junior ◽  
M.M. Lorenzato ◽  
F.W. Roemer ◽  
A. Guermazi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Meniscal Extrusion ◽  
Magnetic Resonance Imaging Assessment
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