scholarly journals MIR 129 5-P AS A NONINVASIVE PROGNOSTIC BIOMARKER OF LIVER FIBROSIS IN HCV EGYPTIAN POPULATION

2019 ◽  
Vol 37 (1) ◽  
pp. 61-74
Keyword(s):  
Liver Fibrosis ◽  
Prognostic Biomarker ◽  
Egyptian Population

scholarly journals microRNA-141 as a diagnostic and prognostic biomarker for prostate cancer in Egyptian population: Pilot study

2018 ◽  
Vol 24 (4) ◽  
pp. 347-352 ◽  
Author(s):  
R. Ali ◽  
S. El Tabbakh ◽  
W. El Delgawy ◽  
A. Kotb ◽  
M.N. Desouky
Keyword(s):  
Prostate Cancer ◽  
Pilot Study ◽  
Prognostic Biomarker ◽  
Egyptian Population

Liver Fibrosis Indices and Hemorrhagic Transformation After Ischemic Stroke

2020 ◽  
Author(s):  
Yanan Wang ◽  
Yajun Cheng ◽  
Ke Qiu ◽  
Quhong Song ◽  
Junfeng Liu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Liver Fibrosis ◽  
Acute Ischemic Stroke ◽  
Primary Outcome ◽  
Prognostic Biomarker ◽  
Hemorrhagic Transformation ◽  
Fibrosis Score ◽  
Multivariate Logistic Regression ◽  
Nonalcoholic Fatty Liver ◽  
Secondary Outcomes

Abstract Background: Hemorrhagic transformation (HT) is recognized as a common compilation of acute ischemic stroke. The aim of this study was to investigate whether liver fibrosis indices are related to HT. Methods: We included ischemic stroke patients within 7 days of symptom onset. We calculated 3 liver fibrosis indices including the Aspartate Aminotransferase - Platelet Ratio Index (APRI), the Fibrosis - 4 (FIB - 4) score, and the Nonalcoholic Fatty Liver Disease Fibrosis Score (NFS) . Primary outcome was HT and secondary outcomes were symptomatic HT or parenchymal hemorrhage. We used multivariate logistic regression to assess the association between liver fibrosis indices and outcomes. Results: Among 2033 patients with ischemic stroke, the median APRI, FIB - 4 and NFS were significantly higher in HT cases compared with controls (APRI: 0.37 vs. 0.31; FIB-4: 2.44 vs. 1.86; 0.13 vs. -0.30, respectively; all P <0.001). After adjustment for potential confounders, the OR (95%CI) of HT for those in the highest tertile of APRI was 1.53 (1.05 - 2.24) compared with patients in the lowest tertile ( P for trend = 0.038). FIB - 4 (OR 1.28, 95% CI 0.82 - 2.01; P for trend = 0.07) and NFS (OR 1.31, 0.71 - 2.44; P for trend = 0.068) were not associated with HT. Indices were not associated with the secondary outcomes. Conclusions: In patients with ischemic stroke, high APRI was associated with increased risks of HT, suggesting that APRI might be a prognostic biomarker for HT after acute ischemic stroke.

Noninvasive Device Measures Liver Fibrosis

2005 ◽  
Vol 35 (6) ◽  
pp. 68-69
Author(s):  
JEFF EVANS
Keyword(s):  
Liver Fibrosis

Protective effect of mixture of Aloe and Silybum on carbon tetrachloride-induced acute hepatotoxicity and liver fibrosis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
YJ Moon ◽  
WC Lee ◽  
SJ Kim ◽  
ST Oh ◽  
EJ Shin ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Fibrosis ◽  
Protective Effect
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