BALANCE IMPAIRMENT IN CHILDREN WITH CHRONIC KIDNEY DISEASES (A CROSS SECTIONAL STUDY).

2019 ◽  
Vol 34 (12) ◽  
pp. 493-503
2019 ◽  
Vol 57 (216) ◽  
Author(s):  
Pankaj Pant ◽  
Santosh Baniya ◽  
Ashish Jha

Introduction: Chronic kidney diseases affect patients with multiple respiratory complications by varied etiopathogenesis adversely affecting the outcome in them. The aim of the study is to find out the respiratory manifestations among patients with chronic kidney disease. Methods: The descriptive cross-sectional study was carried out Tribhuvan University Teaching Hospital from January 2019 to March 2019 after ethical approval. One hundred and two patients with established chronic kidney diseases being treated in a tertiary hospital for a month were included for the study. Clinical evaluation and relevant investigations; chest x ray, pleural fluid analysis, sputum analysis, echocardiography, biochemical investigations and hematological investigations were done to assess the respiratory manifestations of the patients. Results: Pulmonary edema 41 (24.84%) was the most common manifestation followed by pleural effusion 18 (10.9%). Pleural effusions were predominantly bilateral and transudative type. Pneumonia 17 (10.3%) was predominantly lobar pneumonia. Sixteen (9.7%) of the patients were screened positive for obstructive sleep apnea syndrome. Pulmonary tuberculosis was present in 9 (5.45%) patients. Conclusions: Varieties of respiratory complications can present in varied spectrum in patients with chronic kidney diseases and this carries adverse outcome to patient management as well as affects the quality of life of the patient and their family.


2019 ◽  
Vol 72 (4) ◽  
pp. 889-895 ◽  
Author(s):  
Geórgia Alcântara Alencar Melo ◽  
Letícia Lima Aguiar ◽  
Renan Alves Silva ◽  
Glauberto da Silva Quirino ◽  
Ana Karina Bezerra Pinheiro ◽  
...  

ABSTRACT Objective: to analyze the factors related to the impaired comfort of chronic kidney diseases (CKD) patients on hemodialysis. Method: this is a cross-sectional study with 80 patients undergoing hemodialysis in a renal replacement therapy unit through interviews using two instruments, one for clinical and sociodemographic characteristics and the General Comfort Questionnaire, during the hemodialysis session. Mann-Whitney tests and the logistic regression model were used for data analysis. Results: the study found that being younger (p=0.045); being married (p=0.05); and absence of impaired physical mobility (p=0.007) were contributing factors for greater comfort in CKD patients on hemodialysis. Thus, when establishing the odds ratio, it was possible to observe that being 55 years of age or older, being single and having impaired physical mobility represents a 45.7% chance of developing this diagnosis. Conclusions: sociodemographic and clinical variables contribute to the study outcome, demanding attention during the planning of nursing interventions.


2020 ◽  
Author(s):  
Zu-feng Wang ◽  
Nan-hui Zhang ◽  
Ran Luo ◽  
Yi-chun Cheng ◽  
Kang-lin Guo ◽  
...  

Abstract Background: It is controversial about the sex differences in the association of chronic kidney diseases (CKD) and cardiovascular disease (CVD) risk. Thus, we examined CVD risk makers of CKD and non-CKD men and women in China, especially some “non-traditional” ones.Methods: This cross-sectional study used 7999 participants from the China Health and Nutrition Survey in 2009. This study examined the “traditional” risk factors and of CVD, such as lipoprotein cholesterol (LDL-C), total cholesterol (TC) and non-high density lipoprotein cholesterol(non-HDL-C).Also, the “non-traditional” risk factors of CVD were calculated, such as lipoprotein (a)(Lp(a)), white blood cell (WBC) count, visceral adiposity index (VAI) and lipid accumulation product (LAP).Results: Compared with men with CKD, higher levels of TC and LDL-C were observed in women with CKD. Furthermore, compared with men with CKD, the relative difference of WBC count was greater between women with CKD and their non-CKD ones. Meanwhile, the level of LAP and VAI of women with CKD were higher than men with CKD, which indicate the visceral obese. We also observed that the sex by CKD status interactions were statistically significant for TC, LDL-C, non-HDL-C, LAP, VAI and Lp(a) (all p <0.05). After adjusted the covariates, the sex differences effect on CVD risk factors among CKD patients couldn’t be eliminated as well. Conclusions: In CKD situation, women had greater lipid profiles and put on more visceral adiposity than men, which may indicate a higher CVD risk of women with CKD.


BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e040214
Author(s):  
Shan Qin ◽  
Anping Wang ◽  
Shi Gu ◽  
Weiqing Wang ◽  
Zhengnan Gao ◽  
...  

ObjectiveThe relationship between obesity and albuminuria has not been clarified. This study aimed to investigate the correlation between obesity and the urinary albumin-creatinine ratio (UACR) in Southern and Northern China.DesignA descriptive, cross-sectional study.SettingEight regional centres in REACTION (China’s Risk Evaluation of cAncers in Chinese diabeTic Individuals, a lONgitudinal study), including Dalian, Lanzhou, Zhengzhou, Guangzhou, Guangxi, Luzhou, Shanghai and Wuhan.ParticipantsA total of 41 085 patients who were not diagnosed with chronic kidney disease (CKD) and had good compliance were selected according to the inclusion criteria. Patients who were diagnosed with CKD, who had other kidney diseases that could lead to increased urinary protein excretion, who were using angiotensin-converting-enzyme inhibitors or angiotensin II receptor blockers and whose important data were missing were excluded.ResultsParticipants with both, central and peripheral obesity, had a higher risk of elevated UACR, even after adjusting for multiple factors (OR: 1.14, 95% CI: 1.07 to 1.12, p<0.001), and the risk of high UACR in the South was more prominent than that in the North (OR South: 1.22, 95% CI: 1.11 to 1.34; OR North: 1.13, 95% CI: 1.04 to 1.22, p<0.001). The risk was also elevated in the male population, hypertensive individuals, glycosylated haemoglobin (HbA1c)≥6.5% and age ≥60 years in the South. Besides the above groups, diabetes was also a risk factor for the Northern population.ConclusionsIn China, people with both central and peripheral obesity are prone to a high UACR, and the southern population has a higher risk than northern population. Factors such as male sex, hypertension, HbA1c≥6.5% and an age ≥60 years are also risk factors for CKD.


Viruses ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 700 ◽  
Author(s):  
Sarathkumara ◽  
Gamage ◽  
Lokupathirage ◽  
Muthusinghe ◽  
Nanayakkara ◽  
...  

Chronic kidney disease of unknown etiology (CKDu) imposes a substantial burden on public health in Sri Lankan agricultural communities. High seroprevalences of hantavirus have been reported in CKDu patients in several locations of Sri Lanka. We carried out a cross-sectional study followed by an unmatched case-control comparison in two geographically distinct areas of Sri Lanka, Girandurukotte (CKDu endemic) and Kandy (CKDu non-endemic) to determine whether exposure to hantaviruses is a potential risk factor in patients with kidney disease. An indirect immunofluorescent antibody assay using two antigens, Thailand orthohantavirus-infected and recombinant N protein-expressing Vero E6 cells, were used for serodiagnosis. Participants’ demographic and other socio-economic data were collected through a structured questionnaire. Fifty kidney disease patients and 270 controls from Kandy and 104 kidney disease patients and 242 controls from Girandurukotte were examined. Seropositivities were 50% and 17.4% in kidney patients and controls, respectively, in Girandurukotte, and they were 18% and 7% in Kandy. The odds of exposure to hantaviruses were higher for kidney disease patients than for controls in both Girandurukotte (OR:3.66, 95% CI:2.01 to 6.64) and Kandy (OR:2.64, 95% CI:1.07 to 6.54) in binary logistic regression models. According to statistical analysis, individuals exposed to hantaviruses had a higher risk of developing renal impairment. Therefore, hantavirus infection might be an important risk factor for development of kidney disease in Sri Lanka.


Viruses ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1147
Author(s):  
W. Katherine Yih ◽  
Martin Kulldorff ◽  
Jessica H. Leibler ◽  
David J. Friedman ◽  
Daniel R. Brooks

In a recent paper, Sarathkumara et al [...]


Author(s):  
Samira Asadollahi ◽  
Mahta Mazaheri ◽  
Razieh Sadat Tabatabaee ◽  
Sahel Khajehnoori ◽  
Mahmood Noorishadkam ◽  
...  

Background: Congenital abnormalities are diseases that occur during fertilization of the egg or development of the fetus and lead to disability, illness or mortality. This study aimed to investigate the prevalence and the factors associated with fetomaternal abnormalities in therapeutic abortions.                                                                                       Methods: This cross-sectional study was performed on 391 mothers referred to Yazd legal medicine organization for pregnancy termination from March 2017 to March 2020. The data about their fetuses were extracted and recorded. Results:The most common fetal abnormalities observed in this study were central nervous system abnormalities (21.1%), subsequently chromosomal disorders (16.8%), hydropsfetalis, cystic hygroma (15.9%), syndromic disorders (10.1%), single-gene disorders (8.1%), dysmorphology (8.1%), musculoskeletal disorders (7.8%), and cardiovascular disorders (7.2%). Conclusion: The main maternal causes for therapeutic abortion were cardiovascular disease, kidney diseases and cancers, while the most common fetal disorders leading to therapeutic abortion were central nervous system disorders such as anencephaly.


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