scholarly journals TREATMENT OF AGGRESSIVE GIANT CELL TUMOR: INTRALESIONAL CURETTAGE VS RESECTION ENDOPROTHESIS A SYSTEMATIC REVIEW/META ANALYSIS

2020 ◽  
Vol 71 (4) ◽  
pp. 915-926
Author(s):  
Mohamed Mostafa ◽  
Sherif Azmy ◽  
Hany El Sawy
Keyword(s):  
Systematic Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor ◽  
Intralesional Curettage

scholarly journals A Systematic Review and Meta-Analysis of En-Bloc vs Intralesional Resection for Giant Cell Tumor of Bone of the Distal Radius

2013 ◽  
Vol 7 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Theresa J.C Pazionis ◽  
Hussain Alradwan ◽  
Benjamin M Deheshi ◽  
Robert Turcotte ◽  
Forough Farrokhyar ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Distal Radius ◽  
Wrist Joint ◽  
Meta Analysis ◽  
En Bloc Resection ◽  
Cell Tumor ◽  
En Bloc ◽  
Intralesional Curettage ◽  
Functional Benefit

Introduction: Surgical management of Giant Cell Tumor of Bone of the distal radius (GCTDR) remains controversial due to risk of local recurrence (LR) offset by functional limitations which result from en-bloc resection. This study aims to determine the oncologic and functional outcomes of wide excision (WE) vs intralesional curettage (IC) of GCTDR. Methods: A complete search of the applicable literature was done. Included studies reported on patients from the same cohort who were surgically treated for GCTDR with WE or IC. Two reviewers independently assessed all papers. The primary outcome measure was LR. Results: One-hundred-forty-one patients from six studies were included: 60 treated with WE, and 81 with IC. Five WE patients (8%) suffered LR whereas 25 IC patients (31%) did. The odds of LR were three times less in the WE group vs the IC group. MSTS1993 scores, where available, were on average 'good' with WE and 'excellent' with IC. Conclusions: Within statistical limitations the data support an attempt, where feasible, at wrist joint preservation and superior function with IC. Intralesional curettage is reasonable when the functional benefit outweighs the risk of recurrence as is the case in many cases of GCT of the distal radius.

Invasive Giant Cell Tumor of the Lateral Skull Base: A Systematic Review, Meta-Analysis, and Case Illustration

2016 ◽  
Vol 96 ◽  
pp. 47-57 ◽  
Author(s):  
Jacob L. Freeman ◽  
Soliman Oushy ◽  
Jeffrey Schowinsky ◽  
Stefan Sillau ◽  
A. Samy Youssef
Keyword(s):  
Systematic Review ◽  
Skull Base ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor ◽  
Case Illustration ◽  
Lateral Skull Base

scholarly journals Preoperative Denosumab may increase the Risk of Local Recurrence of Giant-cell Tumor of Bone Treated with Curettage: A Systematic Review and Meta-analysis

2021 ◽  
Vol 12 (2) ◽  
pp. 508-517
Author(s):  
Yongzhao Zhao ◽  
Zhenyu Cai ◽  
Xiaodong Tang ◽  
Zhiye Du ◽  
Yi Yang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Local Recurrence ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor

scholarly journals Prognosis of metastatic giant cell tumor of bone in the pre-denosumab era. A systematic review and a meta-analysis

2018 ◽  
Vol 48 (7) ◽  
pp. 640-652 ◽  
Author(s):  
Boris Itkin ◽  
Samanta Straminsky ◽  
Gabriela De Ronato ◽  
Daniel Lewi ◽  
Adolfo Marantz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor

Can p63 serve as a biomarker for diagnosing giant cell tumor of bone? A systematic review and meta-analysis

2020 ◽  
Vol 138 (5) ◽  
pp. 393-399
Author(s):  
Zihao Wan ◽  
Chien-Wei Lee ◽  
Shuai Yuan ◽  
Oscar Kuang-Shen Lee
Keyword(s):  
Systematic Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor

scholarly journals High-Speed Burring with and without the Use of Surgical Adjuvants in the Intralesional Management of Giant Cell Tumor of Bone: A Systematic Review and Meta-Analysis

Sarcoma ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
H. Algawahmed ◽  
Robert Turcotte ◽  
F. Farrokhyar ◽  
M. Ghert
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Local Control ◽  
Fixed Effects ◽  
High Speed ◽  
Meta Analysis ◽  
Cell Tumor ◽  
Fixed Effects Model ◽  
Intralesional Curettage ◽  
Pooled Data

Local control rates for Giant Cell Tumor of Bone (GCT) have been reported in a large number of retrospective series. However, there remains a lack of consensus with respect to the need for a surgical adjuvant when intralesional curettage is performed. We have systematically reviewed the literature and identified six studies in which two groups from the same patient cohort were treated with intralesional curettage and high-speed burring with or without a chemical or thermal adjuvant. Studies were evaluated for quality and pooled data was analyzed using the fixed effects model. Data from 387 patients did not indicate improved local control with the use of surgical adjuvants. Given the available data, we conclude that surgical adjuvants are not required when meticulous tumor removal is performed.

scholarly journals Wide resection versus curettage in giant cell tumor with pathological fracture? A systematic review and meta-analysis

2018 ◽  
Vol 9 ◽  
pp. S15-S18 ◽  
Author(s):  
Abhijeet Ashok Salunke ◽  
Subodh Pathak ◽  
Jaymin Shah ◽  
Jyotindra Pandit ◽  
Vinod Naneria
Keyword(s):  
Systematic Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Pathological Fracture ◽  
Meta Analysis ◽  
Cell Tumor ◽  
Wide Resection

scholarly journals Effect of bisphosphonates on local recurrence of giant cell tumor of bone: a meta-analysis

2019 ◽  
Vol Volume 11 ◽  
pp. 669-680 ◽  
Author(s):  
Mingmin Shi ◽  
Lei Chen ◽  
Yangxin Wang ◽  
Wei Wang ◽  
Yujie Zhang ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Meta Analysis ◽  
Cell Tumor
Sign in / Sign up

Export Citation Format

Share Document