scholarly journals EFFECTIVENESS OF DIFFUSION WEIGHTED MRI DERIVED METRICS IN DIFFERENTIATION OF PEDIATRIC POSTERIOR FOSSA TUMORS

2019 ◽  
Vol 70 (4) ◽  
pp. 243-257
Author(s):  
Eman Darwish ◽  
Aliaa Sheha ◽  
Ahmed Abdelrahman
Keyword(s):  
Posterior Fossa ◽  
Diffusion Weighted Mri ◽  
Posterior Fossa Tumors ◽  
Diffusion Weighted

scholarly journals NI-11 Usefulness of the magnetic resonance imaging arterial spin labeling method for diagnosing posterior fossa hemangioblastoma

2021 ◽  
Vol 3 (Supplement_6) ◽  
pp. vi19-vi20
Author(s):  
Takeshi Hiu ◽  
Ayano Ishiyama ◽  
Minoru Morikawa ◽  
Shiro Baba ◽  
Kenta Ujifuku ◽  
...  
Keyword(s):  
Posterior Fossa ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Dynamic Susceptibility ◽  
Dynamic Susceptibility Contrast ◽  
Posterior Fossa Tumors ◽  
Perfusion Image ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
Contrast Enhanced

Abstract Purpose: It is sometimes challenging to diagnose hemangioblastoma by MRI when the tumor is a solid mass in the posterior fossa. We therefore evaluated perfusion images and diffusion-weighted images to diagnose hemangioblastoma in order to obtain the most useful quantitative features. Methods: Thirty-one posterior fossa tumors whose pathological diagnosis was confirmed by surgery were included in groups A (12 hemangioblastomas) and B (non-hemangioblastoma 19 cases: metastatic tumor 6 cases, pilocytic astrocytoma 3 cases, malignant lymphoma 3 cases, glioblastoma 2 cases, medulloblastoma 2 cases, and other 3 cases). All cases were imaged by 3.0-Tesla MRI, with the apparent diffusion coefficient (ADC) on diffusion-weighted imaging as the parameter, arterial spin labeling (ASL) as the relative value from the CBF map to the region of interest (ROI) in the contralateral hemisphere as perfusion image, dynamic susceptibility contrast (DSC) as rCBF, rCBV, corrected CBV, and K2. The ROI was set to match the contrast-enhanced part, and the two groups were compared and examined. Results: The relative ASL value of group A and the corrected CBV in DSC were significantly higher than group B (p<0.001). In contrast, the ADC showed no marked difference between the two groups. In the distinction between the two groups, the receiver operating characteristic (ROC) analysis showed that the area under the curve (AUC) of the relative ASL value was significantly higher than the other parameters (AUC 0.995, cut-off value 2.34, sensitivity 100%, specificity 99.5%). Discussion/Conclusion: The non-contrast ASL method was extremely useful for diagnosing hemangioblastoma in posterior fossa tumors. The ASL method has been reported helpful for the follow-up of residual tumors or recurrence after surgery. Contrast-enhanced DSC is not always essential for diagnosing posterior fossa hemangioblastoma. It should be noted that measuring the ROI by ASL is difficult when the size of the mural nodule is small.

scholarly journals Comparison of Diffusion-Weighted MRI Reconstruction Methods for Visualization of Cranial Nerves in Posterior Fossa Surgery

2017 ◽  
Vol 11 ◽  
Author(s):  
Brendan Behan ◽  
David Q. Chen ◽  
Francesco Sammartino ◽  
Danielle D. DeSouza ◽  
Erika Wharton-Shukster ◽  
...  
Keyword(s):  
Posterior Fossa ◽  
Cranial Nerves ◽  
Posterior Fossa Surgery ◽  
Diffusion Weighted Mri ◽  
Diffusion Weighted ◽  
Reconstruction Methods ◽  
Mri Reconstruction
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