scholarly journals Clinical efficacy of marbofloxacin in dogs and cats diagnosed with lower urinary tract disorders

2019 ◽  
Vol 75 (05) ◽  
pp. 6269-2019
Author(s):  
BANU DOKUZEYLÜL ◽  
BARAN ÇELIK ◽  
BELGI DIREN SIĞIRCI ◽  
BEREN BAŞARAN KAHRAMAN ◽  
SINEM ÜLGEN SAKA ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Clinical Efficacy ◽  
Lower Urinary Tract ◽  
Small Animal ◽  
Clinical Findings ◽  
Urine Samples ◽  
Urinary Tract Disorders ◽  
Susceptibility Tests ◽  
Tract Infections ◽  
Lower Urinary

Marbofloxacin is one of the fluoroquinolones developed exclusively for veterinary medicine. The primary aim of the present study is to identify and assess evidence for marbofloxacin’s clinical efficacy in the treatment of urinary tract infections in small animal practice. The study included 118 dogs and 123 cats that were referred to the Internal Medicine Department with lower urinary tract symptoms. We excluded animals that had received antimicrobial or anti-inflammatory therapy in the previous 15 days. Diagnosis was confirmed by clinical findings, urinalysis, and imaging. Rectal temperature, appetite, urinary signs, and abdominal pain were monitored during two visits (day 0 and 14). The timetable depended on the diagnosis of the following: two urinalyses, two bacterial examinations, and antibacterial susceptibility testing were performed for each case. Bacterial UTI were confirmed in 36 dogs and 28 cats. Urine samples were collected on day 0, which demonstrated the presence of various bacteria, with a marked predominance of P. mirabilis and coagulase-positive Staphylococci in canine and feline urine samples, respectively. Antimicrobial susceptibility test results revealed 25 (65.7%) of dog isolates and 24 (85.7%) of cat isolates were susceptible to marbofloxacin. Treatment of UTIs is generally challenging for the small animal practitioner. Because of the need for long-term antimicrobials, bacterial culture and susceptibility tests are especially important for successful treatment. Marbofloxacin can be part of an effective treatment of UTIs in dogs and cats.

scholarly journals  Stenotrophomonas maltophilia urinary tract infections in three dogs: a case report

2012 ◽  
Vol 57 (No. 7) ◽  
pp. 380-383 ◽  
Author(s):  
S. Kralova-Kovarikova ◽  
R. Husnik ◽  
D. Honzak ◽  
P. Kohout ◽  
P. Fictum
Keyword(s):  
Case Report ◽  
Urinary Tract ◽  
Stenotrophomonas Maltophilia ◽  
Lower Urinary Tract ◽  
Urine Culture ◽  
Bladder Wall ◽  
Urinary Tract Disorders ◽  
Biopsy Specimens ◽  
Tract Infections ◽  
Lower Urinary

Stenotrophomonas maltophilia was isolated from three dogs with lower urinary tract disorders. The bacterium was cultured from bladder wall biopsy specimens obtained during cystoscopy, whereas urine culture was negative in all cases. The culture of biopsy specimens is useful and may help with the therapy even if diagnosis of the primary disease has been made.    

scholarly journals Epidemiology and antibiotic resistance in community-acquired lower urinary tract infections in the Milan area

2020 ◽  
Vol 35 (2) ◽  
Author(s):  
Daniele Paris ◽  
Mariasofia Caltagirone ◽  
Patrizia Minzulli ◽  
Antonia Valzano ◽  
Fulvio Enrico Ottorino Ferrara ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Lower Urinary Tract ◽  
Susceptibility Testing ◽  
Empirical Treatment ◽  
Urine Samples ◽  
Resistance Patterns ◽  
Tract Infections ◽  
Lower Urinary

Urinary tract infections (UTIs) are among the most common bacterial infectious diseases occurring in the community and healthcare setting. Most community-acquired urinary tract infections are usually treated empirically. The knowledge of antibiotic resistance patterns of the microorganisms causing UTI is essential for defining the empirical treatment. The aim of the present study is to investigate the prevalence and the resistance patterns of bacterial species isolated from lower urinary tract infections, in a large population of Milan area. A retrospective analysis of the isolates obtained from urine samples received at the microbiology laboratory of Centro Diagnostico Italiano of Milan was performed from January 2019 to December 2019. Urine samples were plated on differential medium by automated inoculation system. Identification and antibiotic susceptibility testing were performed using the Phoenix 100™ system. All results were interpreted according to the European Committee on Antimicrobial Susceptibility Testing breakpoints. During a 12-month period a total of the 51,980 urine samples have been processed and 21,4% (11.148) were found to be positive (bacterial count ≥105CFU/mL). Overall Escherichia coli was the most common Gram-negative bacteria of all isolates (72%), followed by Klebsiella pneumoniae (10.8%) and Proteus mirabilis (3.3%). Susceptibility of E. coli to oral antimicrobial agents was demonstrated to be as follows: fosfomycin (97%), trimethoprim/sulfamethoxazole (76%), ciprofloxacin (89%), ampicillin (51%) and amoxicillin/clavulanate (77%). The present study point-out the common antibiotic resistance trend of uropathogens in this area. Our results will help in the formulation of antibiotic policy and determination of empirical treatment of urinary tract infection.

Dynamics of symptoms of genitourinary menopausal syndrome and the frequency of recurrence of lower urinary tract infection in women in periand postmenopausal patients with combined therapy with Trioginal®

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 67-72
Author(s):  
D Yu Pushkar ◽  
M Yu Gvozdev
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urine Culture ◽  
Objective Assessment ◽  
Control Group ◽  
Urination Disorders ◽  
Menopausal Syndrome ◽  
Tract Infections ◽  
Two Stages ◽  
Lower Urinary

Material and methods. The study included patients (n=164) in peri- and postmenopause, having a laboratory-confirmed picture of the genitourinary menopausal syndrome - atrophic vulvovaginitis and suffering from recurrent lower urinary tract infections (UTI) - cystitis and urethritis. All patients underwent standard antibacterial therapy (ABT) UTI in accordance with the results of bacteriological urine culture according to Russian clinical guidelines on urology. Against the background of ABT, 164 patients received additional therapy with Trioginal® (the study group - SG) containing estriol, micronized progesterone and Lactobacillus casei rhamnosus Doderleini 35 (LCR 35) lactobacillus strain. Trioginal® was administered intravaginally in two stages: for 20 days, 2 capsules per day, then for 10 days, 1 capsule per day. In the comparison group - CG (n=67) with ABT, Ovipol Klio® (estriol monopreparation) was additionally intravaginally used in two stages: for 14 days, 1 suppository per day, then for 2 weeks, 1 suppository 2 times a week. The control group consisted of 30 patients receiving only standard ABT UTI, local hormone therapy for vulvovaginal atrophy (VVA) was not performed. The observation period was 12 months after the end of the course of therapy. At all stages of treatment, a subjective and objective assessment of the severity of urination disorders and urogenital atrophy (UDI-6 questionnaire), their impact on the quality of life of patients (questionnaire IIQ-7), indicators of bacteriuria, bacterial urine culture and vaginal biocenosis, frequency of undesirable phenomena were carried out. According to the initial characteristics of the group of patients were comparable. Results. At all stages of the study, in the group of patients who received therapy with the use of the Trioginal® drug, there was a significant improvement in the clinical picture of urination disorders compared to the CG and the control (main) group - MG (in SG - 18% at the end of therapy versus 100% before the start of therapy; CG - 26 % versus 100% respectively; Ledger - 58% versus 100% respectively; p

Recommendations on the Use of Botulinum Toxin in the Treatment of Lower Urinary Tract Disorders and Pelvic Floor Dysfunctions: A European Consensus Report

2009 ◽  
Vol 55 (1) ◽  
pp. 100-120 ◽  
Author(s):  
Apostolos Apostolidis ◽  
Prokar Dasgupta ◽  
Pierre Denys ◽  
Sohier Elneil ◽  
Clare J. Fowler ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Urinary Tract ◽  
Pelvic Floor ◽  
Lower Urinary Tract ◽  
Urinary Tract Disorders ◽  
European Consensus ◽  
Consensus Report ◽  
Lower Urinary
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