scholarly journals Antiviral Activity of Suramin: Inhibitory Effect on Japanese Encephalitis Virus Replication.

1996 ◽  
Vol 24 (2) ◽  
pp. 99-105 ◽  
Author(s):  
KE-SHU XU ◽  
TSUTOMU TAKEGAMI
Keyword(s):  
Antiviral Activity ◽  
Japanese Encephalitis Virus ◽  
Virus Replication ◽  
Japanese Encephalitis ◽  
Inhibitory Effect ◽  
Encephalitis Virus

scholarly journals Antiviral Activity ofIsatis indigoticaExtract and Its Derived Indirubin against Japanese Encephalitis Virus

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Shu-Jen Chang ◽  
Yi-Chih Chang ◽  
Kai-Zen Lu ◽  
Yi-Yun Tsou ◽  
Cheng-Wen Lin
Keyword(s):  
Antiviral Activity ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Antiviral Effect ◽  
Inhibitory Effect ◽  
Encephalitis Virus ◽  
Simultaneous Treatment ◽  
Virus Attachment ◽  
Antiviral Activities

Isatis indigoticais widely used in Chinese Traditional Medicine for clinical treatment of virus infection, tumor, and inflammation, yet its antiviral activities remain unclear. This study probed antiviral activity ofI. indigoticaextract and its marker compounds against Japanese encephalitis virus (JEV).I. indigoticamethanol extract, indigo, and indirubin proved less cytotoxic than other components, showing inhibitory effect (concentration-dependent) on JEV replicationin vitro. Time-of-addition experiments proved the extract, indigo, and indirubin with potent antiviral effect by pretreatment (before infection) or simultaneous treatment (during infection), but not posttreatment (after entry). Antiviral action of these agents showed correlation with blocking virus attachment and exhibited potent virucidal activity. In particular, indirubin had strong protective ability in a mouse model with lethal JEV challenge. The study could yield anti-JEV agents.

scholarly journals Japanese Encephalitis Virus Replication and Inhibitory Effect of shRNA in Mice

2016 ◽  
Vol 06 (06) ◽  
pp. 462-470 ◽  
Author(s):  
Manabu Murakami ◽  
Takafumi Tasaki ◽  
Souichi Nukuzuma ◽  
Hiroshi Minato ◽  
Takayuki Nojima ◽  
...  
Keyword(s):  
Japanese Encephalitis Virus ◽  
Virus Replication ◽  
Japanese Encephalitis ◽  
Inhibitory Effect ◽  
Encephalitis Virus

Inhibitory effect of furanonaphthoquinone derivatives on the replication of Japanese encephalitis virus

1998 ◽  
Vol 37 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Tsutomu Takegami ◽  
Eriko Simamura ◽  
Kei-Ichi Hirai ◽  
Junko Koyama
Keyword(s):  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Inhibitory Effect ◽  
Encephalitis Virus

Inhibitory Effect of RNAi on Japanese Encephalitis Virus ReplicationIn VitroandIn Vivo

2005 ◽  
Vol 49 (12) ◽  
pp. 1047-1056 ◽  
Author(s):  
Manabu Murakami ◽  
Takahide Ota ◽  
Soichi Nukuzuma ◽  
Tsutomu Takegami
Keyword(s):  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Inhibitory Effect ◽  
Encephalitis Virus
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