scholarly journals Relation of Vitamin D with Bone Mineral Density and Bone Turnover Markers in Healthy Saudi Men

2016 ◽  
Vol 4 (4) ◽  
pp. 205-211
Author(s):  
Alhazmi A. S Alhazmi ◽  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Density ◽  
Turnover Markers

25-hydroxy vitamin D levels in healthy premenopausal women: Association with bone turnover markers and bone mineral density

Bone ◽  
2009 ◽  
Vol 45 (3) ◽  
pp. 423-426 ◽  
Author(s):  
Silvano Adami ◽  
Francesco Bertoldo ◽  
Vania Braga ◽  
Elena Fracassi ◽  
Davide Gatti ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Premenopausal Women ◽  
Mineral Density ◽  
Vitamin D Levels ◽  
25 Hydroxy Vitamin D ◽  
Turnover Markers

scholarly journals Prevalence of vitamin D inadequacy and bone turnover markers concerning bone mineral density in older persons

2021 ◽  
Vol 14 (3) ◽  
pp. 397-401
Author(s):  
Abhinav Jha ◽  
◽  
Aditi Singh Tanwar ◽  
Manish Bhargava ◽  
Anil Raj ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Bone Turnover Marker ◽  
Mineral Density ◽  
Vitamin D Levels ◽  
Removable Prosthesis ◽  
Turnover Markers

Owing to the early tooth loss in a large population, the need for removable prosthodontic therapy has widely increased. Loss of teeth can occur due to trauma, periodontal disease, dental caries, and/or oral health negligence. The removable prosthesis is preferred over other teeth replacement methods owing to its cost-effectiveness. However, due to continuous alveolar bone resorption, relining of the removable prosthesis is needed regularly. We aimed to assess the prevalence of vitamin D deficiency and bone turnover marker concerning bone mineral density. Eighty complete denture wearers either in the maxilla or in the mandible or both constituted the study sample. Before the study, all subjects were explained the procedures of the study, and informed consent was obtained before proceeding with the study. Subjects were instructed to provide an early morning sample in a fasting state as serum osteocalcin (OCN) and C-terminal telopeptide (C-Tx) have diurnal variations. Blood samples were collected, and samples were ruled out for 25-OH vitamin D, serum OCN, and C-TX. To determine the association between frequency of relining and bone turnover marker, the collected data were subjected to statistical evaluation. Significant correlations were seen between bone C-Tx, turnover markers (p<0.001), and frequency of denture relining and osteocalcin (p<0.001). No statistically significant effect of gender, vitamin D levels, age, calcium levels, vitamin D supplements, and diabetes was seen on denture relining frequency. The present study concludes that an elevated level of the bone turnover markers such as OCN and C-Tx increases the frequency of relining.

scholarly journals SUN-LB70 Bone Mineral Density, Vitamin D Status and Bone Turnover Markers in Thai Youth With Graves’ Disease: A Pilot Study

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Pattara Wiromrat ◽  
Ouyporn Panamonta
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Thyroid Hormone ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Vitamin D Insufficiency ◽  
Graves Disease ◽  
Mineral Density ◽  
Turnover Markers

Abstract Background: Several studies in adults and limited studies in youth have demonstrated decreased bone mineral density (BMD) and increased bone turnover in people with Graves’ disease (GD) with hyperthyroidism state. These negative impacts on bone loss can be reversed, in some extent, after normalizing of thyroid hormone. Low 25(OH)D was also prevalent in adults with GD that may worsen bone health. However, there has been no study evaluating 25(OH)D and its associations with BMD and markers of bone turnover in youth with GD. Objective: To evaluate BMD, bone turnover markers and 25(OH)D concentrations and the associations among these measures in youth with GD with varying thyroid status. Methods: Thirty participants with GD [age range 8-20 years; female 75%; mean BMI %tile 61±29 kg/m2, median Tanner stage 4 (3, 5)] were included in the study. Seventeen (57%) participants underwent radioactive iodine ablation. Twelve, seven and three participants had hyperthyroidism, euthyroidism/subclinical hypothyroidism and overt hypothyroidism, respectively. Participants were grouped according to free triiodothyronine [FT3] tertiles [low 2.3±0.8; medium 3.5±0.4; high 10.9±0.9 pg/ml]. Lumbar [L-BMD] and total body headless BMD [TBHL-BMD] were measured with Hologic Discovery A densitometry and compared with reference value (BMD z-score, BMDz). Morning serum concentrations of osteocalcin [OC], procollagen type 1 N-terminal propeptide [PINP], β-crosslaps [β-CTX] and 25(OH)D were also analyzed. Results: Mean L-BMDz and TBHL-BMDz in youth with GD were 0.256±1.064 and 0.011±0.898, respectively. Osteopenia was found in only one participant [L-BMDz -1.6 and TBLH-BMDz -1.2] who had thyrotoxicosis. L-BMDz (p=0.713) and TBLH-BMDz (p=0.91) were not significantly different between FT3 tertiles. There were no significant differences in OC [p=0.481], PINP [p=0.37], β-CTX [p=0.71] and 25(OH)D [p=0.91], adjusting for age, sex and BMI %tile, between FT3 tertiles. There were no significant associations among FT3, OC, PINP, β-CTX and BMDz. However, FT3 was negatively correlated with 25(OH)D [r=-0.574, p=0.032]. Participants with GD had mean 25(OH)D of 21.5±5.1 ng/ml. Twenty-nine out of 30 participants (97%) had 25(OH)D concentrations &lt 30 ng/ml. Of these, 11 participants (38%) had 25(OH)D &lt 20 ng/ml. Further, 25(OH)D was associated with L-BMDz [β (95%CI): 0.284 (0.091-0.477), p=0.013] and β-CTX [β (95%CI): 0.078 (0.020-0.136), p=0.011], independent of age, sex and BMI%tile. Conclusions: Vitamin D insufficiency/deficiency is prevalent in Thai youth with GD. Moreover, 25(OH)D concentrations, but not thyroid hormone, is independently associated with spine BMD and bone turnover. Therefore, evaluation and prompt treatment of vitamin D insufficiency/deficiency in pediatric GD are needed to prevent negative skeletal consequences.

scholarly journals Influence of Vitamin D Status on the Effect of Statins on Bone Mineral Density and Bone Turnover Markers in Postmenopausal Women

2014 ◽  
Vol 99 (9) ◽  
pp. 3304-3309 ◽  
Author(s):  
José L. Hernández ◽  
José M. Olmos ◽  
Galo Romaña ◽  
Javier Llorca ◽  
Josefina Martínez ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Turnover Markers

scholarly journals Serum 25-OH Vitamin D in relation to Bone Mineral Density and Bone Turnover

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Nicola Napoli ◽  
Rocky Strollo ◽  
Delia Sprini ◽  
Ernesto Maddaloni ◽  
Giovam Battista Rini ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Femoral Neck ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Density ◽  
Serum 25Ohd ◽  
Turnover Markers

It is unclear which vitamin D status is optimal for bone health. In this study, we aimed to assess cutoffs of 25-hydroxyvitamin D (25OHD) derived by the literature (20, 25, or 30 ng/mL) in relation to bone turnover and bone mineral density (BMD). Serum 25OHD, PTH, osteocalcin, bone alkaline phosphatase, and C-telopeptide were measured in 274 consecutive postmenopausal women. BMD of the lumbar spine (L1–L4) and of femoral neck were also evaluated. 50 patients had normal BMD, while 124 had osteopenia and 100 had osteoporosis. 37.6%, 56.2%, and 70.8% subjects had serum 25OHD lower than 20, 25, or 30 ng/mL, respectively. No differences in bone turnover markers were found when comparing patients with low 25OHD defined according to the different cutoffs. However, a cutoff of 25 ng/mL appeared to differentiate better than a cutoff of 30 ng/mL in those subjects with reduced femoral neck BMD. The PTH plateau occurred at 25OHD levels of 26–30 ng/mL. In conclusion, vitamin D deficiency is common in Sicilian postmenopausal women and it may be associated with low BMD and increased bone turnover markers. Further studies are needed to better define the right cutoff for normal vitamin D levels in postmenopausal women.

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