scholarly journals USE OF GLYCOPYRROLATE AS AN ADJUNCT FOR REDUCTION OF AEROSOL TRANSMISSION OF COVID-19 DURING DENTAL PROCEDURES: A HYPOTHESIS

2020 ◽  
Vol 8 (10) ◽  
pp. 1319-1324
Author(s):  
Rajesh Kumar Routray ◽  
◽  
Kamal Kanta Satapathy ◽  
J. Nitin Samuel ◽  
Ajay Reddy Palle ◽  
...  

COVID-19 global pandemic has become the biggest challenge by causing health crisis across the world due to its contagious nature. Salivary gland acts as a reservoir of virus due to which contaminated saliva plays a pivotal role in COVID-19 transmission among humans. Infection transmission from symptomatic patients as well as asymptomatic carriers is inevitable while performing aerosol generating procedures because contaminated aerosols have potential to float in the air for a considerable amount of time and be inhaled by dentist, dental auxiliary and other patients. Hence, it is a matter of utmost importance to keep upgrading the strategies for prevention of transmission as the outbreak of SARS-COV 2 has clearly placed the health care professionals at highest risk. As excess salivary secretion results in more aerosol contamination in dental procedures, leading to higher risk of transmission antisialogogues can be used to reduce salivary production. This new strategy will be helpful towards reducing aerosol transmission inorder to prevent and control the spread of this highly infectious disease. The aim of this present review is to propose the possible use of antisialogogues (glycopyrrolates) as an adjunct aid in reducing the risk of transmission from contaminated aerosols.

2020 ◽  
Vol 8 (10) ◽  
pp. 1103-1108
Author(s):  
Rajesh Kumar Routray ◽  
◽  
Kamal Kanta Satapathy ◽  
J. Nitin Samuel ◽  
Ajay Reddy Palle ◽  
...  

COVID-19 global pandemic has become the biggest challenge by causing health crisis across the world due to its contagious nature. Salivary gland acts as a reservoir of virus due to which contaminated saliva plays a pivotal role in COVID-19 transmission among humans. Infection transmission from symptomatic patients as well as asymptomatic carriers is inevitable while performing aerosol generating procedures because contaminated aerosols have potential to float in the air for a considerable amount of time and be inhaled by dentist, dental auxiliary and other patients. Hence, it is a matter of utmost importance to keep upgrading the strategies for prevention of transmission as the outbreak of SARS-COV 2 has clearly placed the health care professionals at highest risk. As excess salivary secretion results in more aerosol contamination in dental procedures, leading to higher risk of transmission antisialogogues can be used to reduce salivary production. This new strategy will be helpful towards reducing aerosol transmission inorder to prevent and control the spread of this highly infectious disease. The aim of this present review is to propose the possible use of antisialogogues (glycopyrrolates) as an adjunct aid in reducing the risk of transmission from contaminated aerosols.


Author(s):  
Y. Arockia Suganthi ◽  
Chitra K. ◽  
J. Magelin Mary

Dengue fever is a painful mosquito-borne infection caused by different types of virus in various localities of the world. There is no particular medicine or vaccine to treat person suffering from dengue fever. Dengue viruses are transmitted by the bite of female Aedes (Ae) mosquitoes. Dengue fever viruses are mainly transmitted by Aedes which can be active in tropical or subtropical climates. Aedes Aegypti is the key step to avoid infection transmission to save millions of people in all over the world. This paper provides a standard guideline in the planning of dengue prevention and control measures. At the same time gives the priorities including clinical management and hospitalized dengue patients have to address essentially.


Author(s):  
Aline Cavalcante Santana

The pandemic of the COVID-19 virus brought several changes, including those that shook the world of work. Some transformations were already in progress and others were expected at a later time, leading us to believe that this health crisis would have had an impact on the estimated forecasts for the future of work. This article proposes to outline a reflection on the world of work in the future, considering as a reference the changes that are already in force and comparing them to the predictions highlighted for the decade from 2018 to 2028 through great theoretical references in the areas related to the management of people and technology. The conclusions expose a truth that, in practice, can be inconvenient: this global pandemic forced us to anticipate the agenda related to the future of work and the market - including companies, employees, government agencies and consumers - was not ready for this rupture.


Author(s):  
Dae-Kyum Kim ◽  
Jennifer J. Knapp ◽  
Da Kuang ◽  
Aditya Chawla ◽  
Patricia Cassonnet ◽  
...  

The world is facing a major health crisis, the global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus, for which no approved antiviral agents or vaccines are currently available. Here we describe a collection of codon-optimized coding sequences for SARS-CoV-2 cloned into Gateway-compatible entry vectors, which enable rapid transfer into a variety of expression and tagging vectors. The collection is freely available via Addgene. We hope that widespread availability of this SARS-CoV-2 resource will enable many subsequent molecular studies to better understand the viral life cycle and how to block it.


2020 ◽  
Vol 148 ◽  
Author(s):  
Chen Ling ◽  
Xianjie Wen

Abstract The outbreak of novel coronavirus pneumonia (coronavirus disease 2019 (COVID-19)), declared as a ‘global pandemic’ by the World Health Organization (WHO), is a public health emergency of international concern (PHEIC). The outbreak in multiple locations shows a trend of accelerating spread around the world. China has taken a series of powerful measures to contain the spread of the novel coronavirus. In response to the COVID-19 pandemic, in addition to actively finding effective treatment drugs and developing vaccines, it is more important to identify the source of infection at the community level as soon as possible to block the transmission path of the virus to prevent the spread of the pandemic. The implementation of grid management in the community and the adoption of precise management and control measures to reduce unnecessary personnel movement can effectively reduce the risk of pandemic spread. This paper mainly describes that the grid management mode can promote the refinement and comprehensiveness of community management. As a management system with potential to improve the governance ability of community affairs, it may be helpful to strengthen the prevention and control of the epidemic in the community.


Author(s):  
Mithra N. Hegde

Coronavirus disease 2019 (covid-19) is the most recent HCID (highly contagious infectious diseases) pandemic to hit the world. The respiratory disease (sars-cov-2) has been shown to spread from symptomatic patients through droplets and aerosols. Because of the closed environment and the use of high and low-speed handpieces, ultrasonic scalers, infection spreads even more easily in a dental setting. During these times, our priority should be inward to protect ourselves as well as the patients who need medical attention. Various methods for controlling infection transmission from aerosol-generating dental procedures are recommended to accomplish this. In light of the effect of oral health on the seriousness of the Covid 19 pandemic, and to protect ourselves financially during this pandemic it is critical to explain patients that we dentists are using the most up-to-date approaches to keep them safe by reducing the risk of them contracting the virus from the dental office in order to maximise the number of outpatients. And it is important to treat every patient as a Covid -19 infected person and take the appropriate precautions to ensure our safety while rendering dental treatment.


Author(s):  
Abhishek Kumar Soni

The 2019 novel coronavirus (previously 2019-nCoV) or coronavirus infectious disease 2019 (COVID-19) outbreak has been summarized as on March 29, 2020. COVID-19 is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SERS-CoV-2). The disease was first seen during an outbreak in Wuhan, China and continuous spreading from human to human around the sphere. The disease is uncontrolled and increasing the death toll through. The world is facing a global challenge to protect human lives caused by coronavirus outbreak. The number of infected patients is increasing day by day due to COVID-19 as a pandemic. The world health organization (WHO) has declared global public health emergency on January 30, 2020. The disease has been spread around 201 countries with total confirmed cases 634835 and death cases 29891 as on March 29, 2020. The goal of this review to summaries and update the clinical/medical features and suggestions for diagnosis of the COVID-19 as a pandemic. The discussion of the various therapeutic algorithms, risk, prevention and control based on the latest reports has been provided.


2021 ◽  
Vol 7 (2) ◽  
pp. 284-288
Author(s):  
Pravin M Bhat ◽  
Sunil S Kewat

The SARS-CoV-2 infection has become a global health crisis with an uprising trend of infection and death in the world. Considering the contagious nature and the human to human transmission of the disease, it is utmost important to follow the infection control measures in the ophthalmic practice. The pink eye or conjunctivitis is the associated symptom reported along with the respiratory illness and fever in patients of COVID-19. So the triage policy, using noncontact procedures, understanding the risk factors of the disease, postponement of routine ophthalmic patient’s visit, following respiratory hygiene, hand hygiene, using personal protective equipment (PPE) are some of the measures to keep the infection in control are explained in this article. The surface disinfection, equipment disinfection are also important considering the environmental contamination nature of the disease. So in order to minimize the infection every ophthalmologist should work as per the guidelines and measures and work with the local designated infection control authorities.


Author(s):  
Vilma Andia-Choquepuma ◽  
Daniza Juana Leon-Escobedo ◽  
Himer Avila-George ◽  
orge Sánchez-Garcés ◽  
Ruth Elizabeth Villafuerte-Alcántara ◽  
...  

After the World Health Organization declared the outbreak of Coronavirus (COVID-19) a pandemic, the Peruvian government took preventive measures to counteract the spread of the virus by issuing Supreme Decree No. 008-2020-SA. This decree contains prevention and control measures aimed at ports, airports, land entry points, educational centers, transportation and workplaces.


2021 ◽  
Vol 6 (1) ◽  
pp. 94-106
Author(s):  
Amit Bhandari ◽  
Vanshika Jain ◽  
Rashi Bhandari

Making its first presence in humans in China in late 2019, SARS-CoV-2 has been identified as a highly contagious viral particle causing distress of lower respiratory system, named COVID-19. Since January 2020, there has been a worldwide increase in the number of COVID-19 cases and associated deaths. Owing to the contagious nature of the disease and socializing human culture, the disease has spanned over continents resulting in some countries being more severely affected than others. Since the first knowledge of the disease, interim guidelines have been constantly issued by competent authorities to safeguard the interest of masses and healthcare professionals. As and when new details are procured, these guidelines are adequately modified and circulated. As a standard measure, all individuals are expected to maintain social distancing, cover their face with a mask during any outdoor activity and practice hand hygiene and cough etiquettes. Respiratory droplet spread is the most potential source identified for this uncontrolled disease spread. Being of smaller size, aerosols produced during medical treatment too act a potential source of viral particle dissemination. Almost all dental procedures involve production of aerosols in some form or the other, irrespective of the kind of instrumentation used. Additionally, proximity to the oral cavity, one of the sources of droplet production, poses a high risk of disease contraction by dental healthcare workers and visiting patients. With consideration to dental practice, various guidelines have been issued to minimise and control the spread of COVID-19. This article is written with an aim of reviewing these guidelines and sensitizing and encouraging the dental fraternity to follow them and contribute in the current world health crisis.


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