scholarly journals Central aortic blood pressure, augmentation index, and reflected wave transit time: reproducibility and repeatability of data obtained by oscillometry

2011 ◽  
pp. 649 ◽  
Author(s):  
Olga Ageenkova ◽  
Olga Ageenkova ◽  
Purygina
Keyword(s):  
Blood Pressure ◽  
Transit Time ◽  
Augmentation Index ◽  
Reflected Wave ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

scholarly journals Novel biomarkers of kidney injury and fibrosis in patients with different severity of hypertension: relation to vascular reactivity and stiffness

2019 ◽  
pp. 44-51
Author(s):  
S. A. Mironova ◽  
Yu. S. Yudina ◽  
M. A. Ionov ◽  
N. G. Avdonina ◽  
I. V. Emelyanov ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cystatin C ◽  
Augmentation Index ◽  
Reactive Hyperemia ◽  
Resistive Index ◽  
Serum Cystatin C ◽  
Estimated Gfr ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

Aim. To compare the relationships between conventional and new potentially more early investigational biomarkers (urine and ultrasound) of kidney injury and central aortic blood pressure, vascular stiffness and reactivity, endothelial dysfunction in patients with different severity of hypertension.Material and methods. Urine levels NGAL, KIM-1, L-FABP, albuminuria and serum levels of сystatin C and creatinine were measured in 92 hypertensive patients with mild and severe hypertension, 46 male (mean age 50,7±12,2 years). Glomerular filtration rate was estimated by the level of serum creatinine and cystatin C by MDRD and CKD-EPI formulas. Instrumental examination included measuring office blood pressure, 24-hour ambulatory blood pressure monitoring (SpaceLabs 90207), applanation tonometry (SphygmoCor, Artcor Medical) with the calculation of central aortic blood pressure, pulse wave velocity and augmentation index and Doppler ultrasonography with assessment of intraparenchymal renal arterial resistance indices — resistive index and pulsatility index (Vivid 7 dimension). Endothelial function was assessed by reactive hyperemia index with EndoPAT device (Itamar Medicals).Results. There were no differences in conventional levels of biomarkers between patients, however, cystatin C level increased and serum cystatin C estimated GFR and serum creatinine and cystatin C estimated GFR (CKD EPI formula) (sCr,Cys-estimated GFR) levels decreased with the severity of hypertension. These novel biomarkers were associated with increased central aortic blood pressure, arterial stiffness and intraparenchymal renal arterial resistance indices. Decreased sCr,Cys-estimated GFR levels were associated with lower reactive hyperemia index. There were no differences in NGAL, KIM-1 and L-FABP levels in patients with hypertension. However, NGAL levels were associated with increased augmentation index, resistive index in intralobular and pulsatility index in arcuate arteries, KIM-1 and L-FABP levels were associated with increased systolic and diastolic central aortic blood pressure, pulse wave velocity only in patients with severe and resistant hypertension.Conclusion. Serum cystatin C, NGAL, KIM-1 and L-FABP levels seem to be biomarkers of increased systemic and intrarenal vascular stiffness in patients with different severity of hypertension.

Augmentation index and central aortic blood pressure in patients with abdominal aortic aneurysms

2010 ◽  
Vol 28 (11) ◽  
pp. 2252-2257 ◽  
Author(s):  
Gion Ruegg ◽  
Rebecca H Mason ◽  
Maxine Hardinge ◽  
Jeremy Perkins ◽  
Marc Husmann ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Augmentation Index ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Aortic Blood ◽  
Abdominal Aortic ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

Increased augmentation index and central aortic blood pressure in osteoporotic postmenopausal women

2007 ◽  
Vol 19 (1) ◽  
pp. 49-56 ◽  
Author(s):  
R. A. Mangiafico ◽  
C. Alagona ◽  
P. Pennisi ◽  
N. Parisi ◽  
M. Mangiafico ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Postmenopausal Women ◽  
Augmentation Index ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

scholarly journals Central aortic blood pressure and augmentation index during normal pregnancy

2012 ◽  
Vol 35 (6) ◽  
pp. 633-638 ◽  
Author(s):  
Mika Fujime ◽  
Takuji Tomimatsu ◽  
Yuko Okaue ◽  
Shinsuke Koyama ◽  
Takeshi Kanagawa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Augmentation Index ◽  
Normal Pregnancy ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

Volume status and arterial blood pressures are associated with arterial stiffness in hemodialysis patients

2018 ◽  
Vol 41 (7) ◽  
pp. 378-384 ◽  
Author(s):  
Alper Erdan ◽  
Abdullah Ozkok ◽  
Nadir Alpay ◽  
Vakur Akkaya ◽  
Alaattin Yildiz
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Pressure ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Mean Blood Pressure ◽  
Aortic Blood ◽  
Aortic Blood Pressure

Background: Arterial stiffness is a strong predictor of mortality in hemodialysis patients. In this study, we aimed to investigate possible relations of arterial stiffness with volume status determined by bioimpedance analysis and aortic blood pressure parameters. Also, effects of a single hemodialysis session on these parameters were studied. Methods: A total of 75 hemodialysis patients (M/F: 43/32; mean age: 53 ± 17) were enrolled. Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure were measured by applanation tonometry before and after hemodialysis. Extracellular fluid and total body fluid volumes were determined by bioimpedance analysis. Results: Carotid-femoral pulse wave velocity (9.30 ± 3.30 vs 7.59 ± 2.66 m/s, p < 0.001), augmentation index (24.52 ± 9.42 vs 20.28 ± 10.19, p < 0.001), and aortic pulse pressure (38 ± 14 vs 29 ± 8 mmHg, p < 0.001) significantly decreased after hemodialysis. Pre-dialysis carotid-femoral pulse wave velocity was associated with age (r2 = 0.15, p = 0.01), total cholesterol (r2 = 0.06, p = 0.02), peripheral mean blood pressure (r2 = 0.10, p = 0.005), aortic-mean blood pressure (r2 = 0.06, p = 0.02), aortic pulse pressure (r2 = 0.14, p = 0.001), and extracellular fluid/total body fluid (r2 = 0.30, p < 0.0001). Pre-dialysis augmentation index was associated with total cholesterol (r2 = 0.06, p = 0,02), aortic-mean blood pressure (r2 = 0.16, p < 0.001), and aortic pulse pressure (r2 = 0.22, p < 0.001). Δcarotid-femoral pulse wave velocity was associated with Δaortic-mean blood pressure (r2 = 0.06, p = 0.02) and inversely correlated with baseline carotid-femoral pulse wave velocity (r2 = 0.29, p < 0.001). Pre-dialysis Δaugmentation index was significantly associated with Δaortic-mean blood pressure (r2 = 0.09, p = 0.009) and Δaortic pulse pressure (r2 = 0.06, p = 0.03) and inversely associated with baseline augmentation index (r2 = 0.14, p = 0.001). In multiple linear regression analysis (adjusted R2 = 0.46, p < 0.001) to determine the factors predicting Log carotid-femoral pulse wave velocity, extracellular fluid/total body fluid and peripheral mean blood pressure significantly predicted Log carotid-femoral pulse wave velocity (p = 0.001 and p = 0.006, respectively). Conclusion: Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure significantly decreased after hemodialysis. Arterial stiffness was associated with both peripheral and aortic blood pressure. Furthermore, reduction in arterial stiffness parameters was related to reduction in aortic blood pressure. Pre-dialysis carotid-femoral pulse wave velocity was associated with volume status determined by bioimpedance analysis. Volume control may improve not only the aortic blood pressure measurements but also arterial stiffness in hemodialysis patients.

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