scholarly journals Metabolic Syndrome as a Risk Factor for Sensorineural Hearing Loss in Adult Patients with Turner Syndrome

2020 ◽  
Vol Volume 13 ◽  
pp. 25-35
Author(s):  
Francisco Álvarez-Nava ◽  
Marcia Racines-Orbe ◽  
Julia Witt ◽  
Jessica Guarderas ◽  
Yosselin Vicuña ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Hearing Loss ◽  
Risk Factor ◽  
Sensorineural Hearing Loss ◽  
Turner Syndrome ◽  
Sensorineural Hearing ◽  
Adult Patients

scholarly journals Prognostic factors for outcomes of idiopathic sudden sensorineural hearing loss: protocol for the SeaSHeL national prospective cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e038552
Author(s):  
Rishi Mandavia ◽  
Gerjon Hannink ◽  
Muhammad Nayeem Ahmed ◽  
Yaami Premakumar ◽  
Timothy Shun Man Chu ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cohort Study ◽  
Sensorineural Hearing Loss ◽  
Prospective Cohort Study ◽  
Health Research ◽  
Prospective Cohort ◽  
Prognostic Model ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Adult Patients

IntroductionThe mainstay of treatment for idiopathic sudden sensorineural hearing loss (SSNHL) includes oral steroids, intratympanic steroid injections or a combination of both. The National Institute for Health and Care Excellence, in their recent hearing loss guidelines, highlighted the paucity of evidence assessing the comparative effectiveness of these treatments; and the National Institute for Health Research (NIHR) Health Technology Assessment Programme has since released a commissioned call for a trial to identify the most effective route of administration of steroids as a first-line treatment for idiopathic SSNHL. For such trials to be run effectively, reliable information is needed on patients with SSNHL: where they present, numbers, demographics, treatment pathways, as well as outcomes. This study will collect these data in a nationwide cohort study of patients presenting with SSNHL across 97 National Health Service (NHS) trusts. The study will be delivered through ear, nose and throat (ENT) trainee networks, the NIHR Clinical Research Network (CRN) Audiology Champions and the NIHR CRN. Importantly, this study will also provide a dataset to develop a prognostic model to predict recovery for patients with idiopathic SSNHL. The study objectives are to: (1) map the patient pathway and identify the characteristics of adult patients presenting to NHS ENT and hearing services with SSNHL, (2) develop a prognostic model to predict recovery for patients with idiopathic SSNHL and (3) establish the impact of idiopathic SSNHL on patients’ quality of life (QoL).Methods and analysisStudy design: national multicentre prospective cohort study across 97 NHS trusts.Inclusion criteria: adult patients presenting to NHS ENT and hearing services with SSNHL.Outcomes: change in auditory function; change in QoL score.Analysis: multivariable prognostic model, using prespecified candidate predictors. Mean change in QoL scores will be calculated from initial presentation to follow-up.Ethics and disseminationHealth Research Authority and NHS Research Ethics Committee approved the study. Publication will be on behalf of study sites and collaborators.Trial registration numberClinicalTrials.gov Registry (NCT04108598).

Obesity as a Possible Risk Factor for Pediatric Sensorineural Hearing Loss

2020 ◽  
Author(s):  
Andrew Bluher ◽  
Kosuke Kawai ◽  
Alicia Wang ◽  
Derek Stiles ◽  
Greg Licameli
Keyword(s):  
Hearing Loss ◽  
Risk Factor ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing

scholarly journals Association between metabolic syndrome and sensorineural hearing loss: a cross-sectional study of 11,114 participants

2017 ◽  
Vol Volume 10 ◽  
pp. 459-465 ◽  
Author(s):  
Javad Aghazadeh-Attari ◽  
Behnam Mansorian ◽  
Mohammad Mirza-Aghazadeh-Attari ◽  
Jamal Ahmadzadeh ◽  
Iraj Mohebbi
Keyword(s):  
Metabolic Syndrome ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Cross Sectional Study ◽  
Sensorineural Hearing ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association of Metabolic Syndrome with Sensorineural Hearing Loss

2021 ◽  
Vol 10 (21) ◽  
pp. 4866
Author(s):  
Hwa-Sung Rim ◽  
Myung-Gu Kim ◽  
Dong-Choon Park ◽  
Sung-Soo Kim ◽  
Dae-Woong Kang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Health Examination ◽  
Number Of Components ◽  
The Metabolic Syndrome ◽  
Hearing Thresholds

The prevalence of sensorineural hearing loss has increased along with increases in life expectancy and exposure to noisy environments. Metabolic syndrome (MetS) is a cluster of co-occurring conditions that increase the risk of heart disease, stroke and type 2 diabetes, along with other conditions that affect the blood vessels. Components of MetS include insulin resistance, body weight, lipid concentration, blood pressure, and blood glucose concentration, as well as other features of insulin resistance such as microalbuminuria. MetS has become a major public health problem affecting 20–30% of the global population. This study utilized health examination to investigate whether metabolic syndrome was related to hearing loss. Methods: A total of 94,223 people who underwent health check-ups, including hearing tests, from January 2010 to December 2020 were evaluated. Subjects were divided into two groups, with and without metabolic syndrome. In addition, Scopus, Embase, PubMed, and Cochrane libraries were systematically searched, using keywords such as “hearing loss” and “metabolic syndrome”, for studies that evaluated the relationship between the two. Results: Of the 94,223 subjects, 11,414 (12.1%) had metabolic syndrome and 82,809 did not. The mean ages of subjects in the two groups were 46.1 and 43.9 years, respectively. A comparison of hearing thresholds by age in subjects with and without metabolic syndrome showed that the average pure tone hearing thresholds were significantly higher in subjects with metabolic syndrome than in subjects without it in all age groups. (p < 0.001) Rates of hearing loss in subjects with 0, 1, 2, 3, 4, and 5 of the components of metabolic syndrome were 7.9%, 12.1%, 13.8%, 13.8%, 15.5% and 16.3%, respectively, indicating a significant association between the number of components of metabolic syndrome and the rate of hearing loss (p < 0.0001). The odds ratio of hearing loss was significantly higher in subjects with four components of metabolic syndrome: waist circumference, blood pressure, and triglyceride and fasting blood sugar concentrations (p < 0.0001). (4) Conclusions: The number of components of the metabolic syndrome is positively correlated with the rate of sensorineural hearing loss.

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