scholarly journals Emerging treatments for overactive bladder: clinical potential of botulinum toxins

2014 ◽  
pp. 51 ◽  
Author(s):  
Douglas Tincello ◽  
Tina Rashid ◽  
Vladimir Revicky
Keyword(s):  
Overactive Bladder ◽  
Botulinum Toxins ◽  
Emerging Treatments ◽  
Clinical Potential

scholarly journals Botulinum Toxin Use in the Lower Urinary Tract

2007 ◽  
Vol 7 ◽  
pp. 808-817
Author(s):  
Shelby N. Morrisroe ◽  
Michael B. Chancellor
Keyword(s):  
Botulinum Toxin ◽  
Urinary Tract ◽  
Overactive Bladder ◽  
Lower Urinary Tract ◽  
Botulinum Neurotoxin ◽  
Botulinum Toxins ◽  
Muscle Paralysis ◽  
Botulinum Neurotoxin A ◽  
Beneficial Effects ◽  
Lower Urinary

Botulinum toxins are well known for their ability to disrupt neurotransmission and cause muscle paralysis. Recently, urologists have discovered their beneficial effects in patients with neurogenic and overactive bladder conditions. This review is intended to provide a quick overview for urologists of the structure, function, and clinical uses of botulinum neurotoxin A in the lower urinary tract.

Characteristics of the Frequency-Following Response to Speech in Neonates and Potential Applicability in Clinical Practice: A Systematic Review

2020 ◽  
Vol 63 (5) ◽  
pp. 1618-1635
Author(s):  
Céline Richard ◽  
Mary Lauren Neel ◽  
Arnaud Jeanvoine ◽  
Sharon Mc Connell ◽  
Alison Gehred ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cochrane Library ◽  
Neurodevelopmental Outcomes ◽  
Frequency Following Response ◽  
Ovid Medline ◽  
Published Evidence ◽  
Mesh Terms ◽  
Potential Applicability ◽  
Clinical Potential

Purpose We sought to critically analyze and evaluate published evidence regarding feasibility and clinical potential for predicting neurodevelopmental outcomes of the frequency-following responses (FFRs) to speech recordings in neonates (birth to 28 days). Method A systematic search of MeSH terms in the Cumulative Index to Nursing and Allied HealthLiterature, Embase, Google Scholar, Ovid Medline (R) and E-Pub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily, Web of Science, SCOPUS, COCHRANE Library, and ClinicalTrials.gov was performed. Manual review of all items identified in the search was performed by two independent reviewers. Articles were evaluated based on the level of methodological quality and evidence according to the RTI item bank. Results Seven articles met inclusion criteria. None of the included studies reported neurodevelopmental outcomes past 3 months of age. Quality of the evidence ranged from moderate to high. Protocol variations were frequent. Conclusions Based on this systematic review, the FFR to speech can capture both temporal and spectral acoustic features in neonates. It can accurately be recorded in a fast and easy manner at the infant's bedside. However, at this time, further studies are needed to identify and validate which FFR features could be incorporated as an addition to standard evaluation of infant sound processing evaluation in subcortico-cortical networks. This review identifies the need for further research focused on identifying specific features of the neonatal FFRs, those with predictive value for early childhood outcomes to help guide targeted early speech and hearing interventions.

257: The Phosphodiesterase Type 4 Inhibitor, Rolipram, is More Efficient to Relax Detrusor Smooth Muscle in Rats with Overactive Bladder than in Control Rats

2007 ◽  
Vol 177 (4S) ◽  
pp. 86-86
Author(s):  
Stephanie Oger ◽  
Delphine Behr-Roussel ◽  
Katell Mevel ◽  
Jacques Bernabe ◽  
Pierre Denys ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Overactive Bladder ◽  
Detrusor Smooth Muscle ◽  
Phosphodiesterase Type

1678: Experiences Including 5 Year Results of 180 Cases Treated with Low-Dose (100 U) Botulinum-A Toxin Injections into the Detrusor Muscle for Overactive Bladder Refractory to Anticholinergics

2007 ◽  
Vol 177 (4S) ◽  
pp. 556-557 ◽  
Author(s):  
Daniel M. Schmid ◽  
Peter Sauermann ◽  
Matthias Werner ◽  
Daniele Perucchini ◽  
Tullio Sulser ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Low Dose ◽  
Detrusor Muscle ◽  
Botulinum A Toxin

299: The Expressions of Multiple Angiogenic Factors in Bladder Epithelium in Patients with Refractory Overactive Bladder

2005 ◽  
Vol 173 (4S) ◽  
pp. 82-83
Author(s):  
Masahiro Tamaki ◽  
Tadashi Hayashi ◽  
Osamu Ogawa ◽  
Tomohiro Ueda ◽  
Naoki Yoshimura
Keyword(s):  
Overactive Bladder ◽  
Angiogenic Factors ◽  
Bladder Epithelium
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