scholarly journals Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia

2019 ◽  
Vol Volume 11 ◽  
pp. 1-8 ◽  
Author(s):  
Marcello Henrique Araujo Da Silva ◽  
Diogo Benchimol De Souza
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Sex Hormones ◽  
Steroid Receptors ◽  
Prostatic Hyperplasia ◽  
Sex Steroid ◽  
Current Evidence ◽  
Sex Steroid Receptors

scholarly journals Ovarian sex steroid receptors and sex hormones in androgenized rats

Reproduction ◽  
2016 ◽  
Vol 152 (5) ◽  
pp. 545-559 ◽  
Author(s):  
Vinícius Augusto Simão ◽  
Luiz Gustavo de Almeida Chuffa ◽  
Isabel Cristina Cherici Camargo
Keyword(s):  
Sex Hormones ◽  
Steroid Receptors ◽  
Serum Levels ◽  
Sex Steroid ◽  
Control Group ◽  
Dependent Manner ◽  
Adult Rats ◽  
Sex Steroid Receptors ◽  
17Β Estradiol ◽  
First Time

This study evaluated for the first time the effects of different doses of the anabolic steroid nandrolone decanoate (ND) on the expression of ovarian steroid receptors (AR, ER-α (ESR1) and ER-β (ESR2)) and related sex hormones after treatment and recovery periods in adult rats. The animals were injected subcutaneously with doses of ND (1.87, 3.75, 7.5 or 15 mg/kg b.w.) or mineral oil (control group) for 15 days, and the experimental groups were divided into three periods of evaluation: (a) ND treatment for 15 days, (b) ND treatment and recovery for a period of 30 days and (c) ND treatment and recovery for a period of 60 days. Estrous cycle was monitored daily. At the end of each period, rats were killed for collection of blood and ovaries. Persistent diestrus occurred in all rats during ND treatment and after 30-day recovery. The highest dose of ND was able to maintain all rats arrested at diestrus until 60-day recovery. The expression of steroid receptors varied in a dose- and period-dependent manner, having a more pronounced response with the dose of 15 mg ND/kg. ND treatment increased serum levels of testosterone, 17β-estradiol and dihydrotestosterone, especially at the highest doses of 7.5 and 15 mg ND/kg. No change was observed in the levels of follicle-stimulating hormone (FSH), whereas levels of the luteinizing hormone (LH) varied according to the dose and period. In conclusion, the ovarian sex steroid receptors and sex hormones were restored only at lower doses of ND and after a longer period of recovery.

scholarly journals P-96 Levels of sex hormones and sex steroid receptors in pathological tissues in gastric cancer patients

2020 ◽  
Vol 31 ◽  
pp. S120-S121
Author(s):  
O. Kit ◽  
E. Frantsiyants ◽  
V. Bandovkina ◽  
Y. Gevorkyan ◽  
N. Soldatkina ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Sex Hormones ◽  
Steroid Receptors ◽  
Sex Steroid ◽  
Sex Steroid Receptors ◽  
Gastric Cancer Patients ◽  
Pathological Tissues

Antagonism by Progesterone of Diethylstilbestrol-lnduced Pituitary Tumorigenesis in Fischer 344 Rats: Effects on Sex Steroid Receptors and Tyrosine Hydroxylase mRNA

1996 ◽  
Vol 63 (6) ◽  
pp. 530-539 ◽  
Author(s):  
Gerardo G. Piroli ◽  
Claudia A. Grillo ◽  
Monica G. Ferrini ◽  
Victoria Lux-Lantos ◽  
Alejandro F. De Nicola
Keyword(s):  
Tyrosine Hydroxylase ◽  
Steroid Receptors ◽  
Sex Steroid ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Sex Steroid Receptors ◽  
Pituitary Tumorigenesis

484 Sex steroid receptors in 53 human CNS neuroepithelial tumors

1983 ◽  
Vol 19 ◽  
pp. 166
Author(s):  
J. Hassoun ◽  
P.M. Martin ◽  
R.P. Vigouroux ◽  
M. Toga ◽  
M. Moguilewsky ◽  
...  
Keyword(s):  
Steroid Receptors ◽  
Sex Steroid ◽  
Neuroepithelial Tumors ◽  
Sex Steroid Receptors

scholarly journals Role of sex steroid receptors in pathobiology of hepatocellular carcinoma

2008 ◽  
Vol 14 (39) ◽  
pp. 5945 ◽  
Author(s):  
Mamta Kalra ◽  
Jary Mayes ◽  
Senait Assefa ◽  
Anil K Kaul ◽  
Rashmi Kaul
Keyword(s):  
Hepatocellular Carcinoma ◽  
Steroid Receptors ◽  
Sex Steroid ◽  
Sex Steroid Receptors
Sign in / Sign up

Export Citation Format

Share Document