scholarly journals Role of PPARγ in the nutritional and pharmacological actions of carotenoids

Author(s):  
Wen-en Zhao ◽  
Guoqing Shi ◽  
Huihui Gu ◽  
Ba Ngoc Nguyen
Keyword(s):  
2019 ◽  
Vol 854 ◽  
pp. 272-281 ◽  
Author(s):  
Adriana Ribeiro Silva ◽  
Cassiano Felippe Gonçalves-de-Albuquerque ◽  
Ana Rosa Pérez ◽  
Vinicius de Frias Carvalho

2008 ◽  
Vol 22 (5-6) ◽  
pp. 549-556 ◽  
Author(s):  
Francisco J.O. Rios ◽  
Sonia Jancar ◽  
Ivo B. Melo ◽  
Daniel F.J. Ketelhuth ◽  
Magnus Gidlund
Keyword(s):  

2021 ◽  
Vol 22 (16) ◽  
pp. 8876
Author(s):  
Pierre Layrolle ◽  
Pierre Payoux ◽  
Stéphane Chavanas

Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a master regulator of metabolism, adipogenesis, inflammation and cell cycle, and it has been extensively studied in the brain in relation to inflammation or neurodegeneration. Little is known however about its role in viral infections of the brain parenchyma, although they represent the most frequent cause of encephalitis and are a major threat for the developing brain. Specific to viral infections is the ability to subvert signaling pathways of the host cell to ensure virus replication and spreading, as deleterious as the consequences may be for the host. In this respect, the pleiotropic role of PPARγ makes it a critical target of infection. This review aims to provide an update on the role of PPARγ in viral infections of the brain. Recent studies have highlighted the involvement of PPARγ in brain or neural cells infected by immunodeficiency virus 1, Zika virus, or human cytomegalovirus. They have provided a better understanding on PPARγ functions in the infected brain, and revealed that it can be a double-edged sword with respect to inflammation, viral replication, or neuronogenesis. They unraveled new roles of PPARγ in health and disease and could possibly help designing new therapeutic strategies.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Barbara Moura Antunes ◽  
José Cesar Rosa-Neto ◽  
Helena Angélica Pereira Batatinha ◽  
Emerson Franchini ◽  
Ana Maria Teixeira ◽  
...  

2011 ◽  
Vol 224 (2) ◽  
pp. 336-343 ◽  
Author(s):  
Mohammad Salehi Sadaghiani ◽  
Mehrak Javadi-Paydar ◽  
Mohammad Hadi Gharedaghi ◽  
Yashar Yousefzadeh Fard ◽  
Ahmad Reza Dehpour

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S284-S285
Author(s):  
R. Chee ◽  
D. Kaye ◽  
J. P.F. Chin-Dusting ◽  
K. Moe
Keyword(s):  

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