scholarly journals Use of dynamic contrast enhanced time intensity curve shape analysis in MRI: theory and practice

2013 ◽  
pp. 71 ◽  
Author(s):  
Cristina Lavini ◽  
Buiter ◽  
Maas
Radiology ◽  
2009 ◽  
Vol 253 (1) ◽  
pp. 234-240 ◽  
Author(s):  
Christiaan van der Leij ◽  
Marleen G. H. van de Sande ◽  
Cristina Lavini ◽  
Paul P. Tak ◽  
Mario Maas

2015 ◽  
Vol 42 (6) ◽  
pp. 1497-1506 ◽  
Author(s):  
Christiaan van der Leij ◽  
Cristina Lavini ◽  
Marleen G.H. van de Sande ◽  
Marjolein J.H. de Hair ◽  
Christophe Wijffels ◽  
...  

2022 ◽  
Vol 9 (1) ◽  
pp. 17-27
Author(s):  
Raghavendra H K ◽  
Alpana Manchanda ◽  
Anju Garg

Introduction: Magnetic resonance imaging (MRI) is a widely used imaging modality in the imaging evaluation of carcinoma of cervix. The aim of our study was to evaluate the response in carcinoma cervix patients following chemoradiotherapy by Diffusion weighted (DW-MRI) and Dynamic contrast enhanced-MRI (DCE-MRI). Methods: 21 inoperable biopsy proven patients (mean age 48.43 years) of carcinoma cervix were included in the study. All patients underwent MRI (conventional, DW and DCE) of the pelvis thrice. Baseline MRI, Post chemotherapy MRI after neoadjuvant chemotherapy and Post chemoradiotherapy MRI after completion of concurrent chemoradiotherapy. Post treatment apparent diffusion coefficient(ADC) values and Time intensity curve(TIC) pattern were compared with baseline values. Results: Baseline meanADC value of all patients was 0.82 x10-3 mm2/s. After completion of treatment, 18 patients showed complete resolution of tumor and showed 0.50 x10-3 mm2/s increase in meanADC value from baseline MRI which was significantly higher than remaining 3 patients with residual tumor (0.50 x10-3 mm2/s v/s 0.17 x10-3 mm2/s). ADC threshold value of 1.15 x10-3 mm2/s was defined, differentiating the residual tumor from the healthy cervical tissue after chemoradiation. On post treatment MRI, 17 out of 18 patients with complete resolution of tumor showed increasing trend of enhancement on TIC and only one patient showed plateau pattern. 2 of the 3 patients with residual tumor showed washout pattern and one patient showed plateau pattern. Conclusion: ADC values and TIC pattern differ in patients with complete response to chemoradiotherapy from patients with residual tumor, so helps in differentiating residual tumor from cancer free cervix. Keywords: Carcinoma of cervix; Chemoradiotherapy; Diffusion weighted MRI; Dynamic contrast enhanced MRI; Time intensity curve.


2016 ◽  
Vol 89 (1061) ◽  
pp. 20151000 ◽  
Author(s):  
Taro Sakashita ◽  
Tamotsu Kamishima ◽  
Yuto Kobayashi ◽  
Hiroyuki Sugimori ◽  
Minghui Tang ◽  
...  

Rheumatology ◽  
2012 ◽  
Vol 51 (7) ◽  
pp. 1240-1245 ◽  
Author(s):  
M. G. H. van de Sande ◽  
C. van der Leij ◽  
C. Lavini ◽  
C. A. Wijbrandts ◽  
M. Maas ◽  
...  

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