scholarly journals Adjunctive Statin Therapy Reduces Mortality After Acute Hemorrhagic Stroke

2021 ◽  
Vol Volume 14 ◽  
pp. 177-183
Author(s):  
Cheng-Kai Lin ◽  
Po-Yuan Chen ◽  
Yu-ying Wu ◽  
Cheng-Chun Wu ◽  
Han-Jung Chen ◽  
...  
Keyword(s):  
Statin Therapy ◽  
Hemorrhagic Stroke ◽  
Acute Hemorrhagic Stroke

Inhibiting ER Stress Weakens Neuronal Pyroptosis in a Mouse Acute Hemorrhagic Stroke Model

2020 ◽  
Vol 57 (12) ◽  
pp. 5324-5335
Author(s):  
Guang Chen ◽  
Cheng Gao ◽  
Ya’nan Yan ◽  
Tao Wang ◽  
Chengliang Luo ◽  
...  
Keyword(s):  
Er Stress ◽  
Hemorrhagic Stroke ◽  
Stroke Model ◽  
Acute Hemorrhagic Stroke

scholarly journals Does statin increase the risk of intracerebral hemorrhage in stroke survivors? A meta-analysis and trial sequential analysis

2019 ◽  
Vol 12 ◽  
pp. 175628641986483 ◽  
Author(s):  
Ru Jian Jonathan Teoh ◽  
Chi-Jung Huang ◽  
Chi Peng Chan ◽  
Li-Yin Chien ◽  
Chih-Ping Chung ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Intracerebral Hemorrhage ◽  
Statin Therapy ◽  
Sequential Analysis ◽  
Hemorrhagic Stroke ◽  
Stroke Risk ◽  
Meta Analysis ◽  
Trial Sequential Analysis ◽  
Stroke Survivors ◽  
Composite Endpoints

Background: It remains debatable whether statin increases the risk of intracerebral hemorrhage (ICH) in poststroke patients. Methods: We systematically searched PubMed, EMBASE, and CENTRAL for randomized controlled trials. Trial sequential analysis (TSA) was conducted to assess the reliability and conclusiveness of the available evidence in the meta-analysis. To evaluate the overall effectiveness, the net composite endpoints were derived by totaling ischemic stroke, hemorrhagic stroke, transient ischemic attack (TIA), myocardial infarction, and cardiovascular mortality. Results: A total of 17 trials with 11,576 subjects with previous ischemic stroke, TIA, or ICH were included, in which statin therapy increased the risk of hemorrhagic stroke (risk ratio [RR], 1.42; 95% confidence interval [CI], 1.07–1.87), but reduced the risk of ischemic stroke (RR, 0.85; 95% CI, 0.75–0.95). For the net composite endpoints, statin therapy was associated with a 17% risk reduction (95% CI, 12–21%; number needed to treat = 6). With a control event rate 2% and RR increase 40%, the TSA suggested a conclusive signal of an increased risk of hemorrhagic stroke in stroke survivors taking statin. However, with the sensitivity analysis by changing assumptions, the conclusions about hemorrhagic stroke risk were less robust. Conclusions: Statin therapy in poststroke patients increased the risk of hemorrhagic stroke but effectively reduced ischemic stroke risk. Weighing the benefits and potential harms, statin has an overall beneficial effect in patients with previous stroke or TIA. However, more studies are required to investigate the conclusiveness of the increased hemorrhagic stroke risk revealed in our study.

Occult infarct with acute hemorrhagic stroke in juvenile diabetic ketoacidosis

2008 ◽  
Vol 30 (1) ◽  
pp. 91-93 ◽  
Author(s):  
Jainn-Jim Lin ◽  
Kuang-Lin Lin ◽  
Huei-Shyong Wang ◽  
Alex Mun-Ching Wong ◽  
Shao-Hsuan Hsia
Keyword(s):  
Diabetic Ketoacidosis ◽  
Hemorrhagic Stroke ◽  
Juvenile Diabetic ◽  
Acute Hemorrhagic Stroke

scholarly journals Risk factors for medical complications of acute hemorrhagic stroke

2015 ◽  
Vol 4 (3) ◽  
pp. 222-225 ◽  
Author(s):  
Jangala Mohan Sidhartha ◽  
Aravinda Reddy Purma ◽  
Lomati Venkata Pavan Kumar Reddy ◽  
Nagaswaram Krupa Sagar ◽  
Marri Prabhu Teja ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hemorrhagic Stroke ◽  
Medical Complications ◽  
Acute Hemorrhagic Stroke

The Patterns of Antihypertensive Drugs use in Acute Hemorrhagic Stroke Patients

2020 ◽  
Vol 13 (2) ◽  
pp. 547
Author(s):  
Din Amalia Widyaningrum ◽  
Wenny Putri Nilamsari ◽  
Wardah Rahmatul Islamiyah ◽  
Dewi Wara Shinta
Keyword(s):  
Hemorrhagic Stroke ◽  
Antihypertensive Drugs ◽  
Stroke Patients ◽  
Acute Hemorrhagic Stroke
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