scholarly journals Rate and Treatment of Retinopathy of Prematurity in Extremely Low Birth Weight Infants with Gestational Age ≤28 Weeks in Eastern China

2020 ◽  
Vol Volume 13 ◽  
pp. 2867-2873
Author(s):  
Meng Zhang ◽  
Gezhi Xu ◽  
Xin Wang ◽  
Yingqin Ni ◽  
Xin Huang
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Eastern China ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
P Rate

scholarly journals Az extrém alacsony születési súlyú koraszülöttek hyperglykaemiájának korai és késői szövődményei

2019 ◽  
Vol 160 (32) ◽  
pp. 1270-1278
Author(s):  
Réka Turai ◽  
Márton Ferenc Schandl ◽  
Timea Dergez ◽  
Réka Anna Vass ◽  
Tímea Kvárik ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Animal Studies ◽  
Extremely Low Birth Weight ◽  
Sprague Dawley ◽  
Low Birth Weight Infants ◽  
Sprague Dawley Rats ◽  
Neonatal Hyperglycemia

Abstract: Introduction: During recent decades, the perinatal mortality of extremely low-birth weight infants has decreased. An important task is to recognize complications of prematurity. Aim: We made an attempt to explore the relationship between complications of prematurity and neonatal hyperglycemia. Method: From 1 January 2014 to 31 December 2017, 188 infants with birth weight below 1000 g were admitted. For each infant, the frequencies of hyperglycemia (blood glucose >8.5 mmol/l), retinopathy of prematurity, intraventricular hemorrhage, and bronchopulmonary dysplasia were determined. Animal studies were performed in Sprague Dawley rats. Hyperglycemia was achieved by intraperitoneal injection of streptozotocin (100 mg/kg). On the 7th day of life, aorta sections were prepared and stained with hematoxylin eosin. Wall thickness was measured using QCapture Pro 7 image analysis software. Results: The mean ± SD gestational age and birth weight were 27.1 ± 2.2 weeks and 814.9 ± 151.9 g; 33 infants (17.5%) died. Hyperglycemia was confirmed in 62 cases (32.9%), and insulin treatment was given to 43 infants (22.8%). The gestational age and birth weight of the hyperglycemic infants were significantly lower (p<0.001), the incidence of severe retinopathy (p = 0.012) and the mortality of insulin-treated patients were higher (p = 0.02) than in normoglycemic infants. Among survivors (n = 155), we found by logistic regression analysis that hyperglycemia was a risk factor for severe retinopathy (p<0.001). In the rat model, neonatal hyperglycemia caused significant thickening of the aortic wall. Conclusion: Our studies indicate that hyperglycemia is common in extremely low birth-weight infants. Monitoring of these infants for retinopathy of prematurity, kidney dysfunction, and hypertension is recommended. Orv Hetil. 2019; 160(32): 1270–1278.

scholarly journals Genetic Variants Associated With Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

2014 ◽  
Vol 55 (10) ◽  
pp. 6194 ◽  
Author(s):  
M. Elizabeth Hartnett ◽  
Margaux A. Morrison ◽  
Silvia Smith ◽  
Tammy L. Yanovitch ◽  
Terri L. Young ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Genetic Variants ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants

scholarly journals The risk factors and progression of retinopathy of prematurity in extremely low birth weight infants

2021 ◽  
Vol 24 (3) ◽  
pp. 181-186
Author(s):  
Igor I. Dyumin ◽  
Elena A. Balakireva ◽  
Elena A. Yaroshevich ◽  
Aleksey I. Sevostyanov ◽  
Igor V. Nikolaenko
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Premature Babies ◽  
Ectopic Pregnancies

The number of premature babies, including those with extremely low birth weight (ELBW), is steadily growing every year. In surviving ELBW infants, retinopathy of prematurity (ROP) more often develops, which has a more severe course, depending not only on the degree of immaturity and somatic burden of premature babies but also on the quality of nursing. The aim of this work is to determine the risk factors for ROP progression in profoundly premature ELBW infants to optimize the tactics of their treatment. Materials and methods. We studied the case histories of 155 surviving premature ELBW infants with ROP of various stages treated in perinatal centres of the Belgorod region in 2014-2019. Results. In premature ELBW infants, ROP of varying severity was found to be diagnosed in 90% of cases. The anamnesis of the mothers of the examined patients with moderate and severe ROP was dominated by unfavorable preceding pregnancies (miscarriages, silent miscarriage and ectopic pregnancies, medical abortions).The need for preterm infants in mechanical ventilation was established to depend on the severity of ROP and the duration of mechanical ventilation (p < 0.05). Frequent, not always justified red blood transfusions leading to the replacement of fetal haemoglobin with adult haemoglobin are also essential factors in ROP progression.

Reticulocyte Count: The Forgotten Factor in Transfusion Decisions for Extremely Low Birth Weight Infants

2021 ◽  
Author(s):  
Daniel Nakhla ◽  
Alla Kushnir ◽  
Rafat Ahmed ◽  
Vineet Bhandari ◽  
Krystal Hunter ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Reticulocyte Count ◽  
Retrospective Chart Review ◽  
Extremely Low Birth Weight ◽  
Positive Trend ◽  
Reference Ranges ◽  
Low Birth Weight Infants ◽  
Packed Red Blood Cells

Background: Extremely low birth weight (ELBW) infants often receive transfusions of packed red blood cells. Long-term outcomes of infants treated with liberal versus restricted transfusion criteria have been evaluated with conflicting results. Clinicians incorporate a reticulocyte count (RC) in their transfusion decisions. There is a lack of information on reference ranges for RCs in growing ELBW infants and whether infant’s chronologic age or corrected gestational age generates a specific trend in the RCs. Objective: Our aim was to evaluate the levels of RCs obtained from ELBW infants over the course of the initial hospitalization. Study Design: A retrospective chart review of ELBW infants treated in the neonatal intensive care unit and had RCs performed. We analyzed the RCs to observe trends based on the chronologic age and corrected gestational age. Results: A total of 738 RCs were analyzed. A positive trend in RCs that reached a peak at 32-34 weeks corrected gestational age and then experienced a downward trend was observed. Conclusions: Our report examines a very common hematologic test that is theoretically helpful but is in need of guidelines concerning the appropriate frequency of testing and its utility in making transfusion decisions in ELBW infants.

scholarly journals The Effect of Anemia on Retinopathy of Prematurity in Extremely Low Birth Weight Infants

2001 ◽  
Vol 21 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Judith A Englert ◽  
Richard A Saunders ◽  
Dilip Purohit ◽  
Thomas C Hulsey ◽  
Myla Ebeling
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants
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