scholarly journals Management of guttate psoriasis in patients with associated streptococcal infection

2012 ◽  
pp. 89 ◽  
Author(s):  
Ozlem Karabudak Abuaf ◽  
Dogan
2017 ◽  
Vol 42 (5) ◽  
pp. 536-538 ◽  
Author(s):  
F. M. Garritsen ◽  
D. E. Kraag ◽  
M. de Graaf

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Julieta D. P. Dotulong ◽  
Charly M. M. Korompis ◽  
Herry E. J. Pandaleke

Abstract: Guttate psoriasis (GP) is a variant of psoriasis with typical drop-shaped lesions sized 0.5-1 cm in diameter, localized especially in the upper part of the body and proximal extremities. It usually occurs in young adult. We reported a female,11 years old, with red, itchy, and scaly patches distributed nearly all over the body. There was a history of sore throat. Dermatologic status showed multiple erythematous plaques which were miliar to numular, discrete, and were covered with layered silvery white scales. The Auspitz sign, wax spot phenomenon, and ASTO were positive. The histopathologic examination showed para-keratosis and Munro microabcesses. The patient treated with topical steroid for 4 weeks made improvement. Conclusion: In this case, diagnosis of guttate psoriasis was based on anamnesis, examination, and supporting examinations. Streptococcal infection was suspected as the trigger factor due to the positive ASTO examination. Topical steroid as the first line therapy for mild to moderate psoriasis made great improvement.Keywords: guttate psoriasis, streptococcal infectionAbstrak: Psoriasis gutata (PG) merupakan varian dari psoriasis. Gambaran khasnya seperti tetesan air dengan diameter 0,5-1 cm, di badan bagian atas dan ekstremitas proksimal. Sering terjadi pada dewasa muda. Kami melaporkan kasus seorang perempuan berusia 11 tahun dengan bercak merah meninggi, bersisik, disertai gatal pada hampir seluruh tubuh. Riwayat nyeri menelan positif. Riwayat pengobatan sebelumnya disangkal. Status dermatologis ditemukan plak eritem, multipel, miliar-numular, diskret, ditutupi skuama berlapis warna putih keperakan. Pemeriksaan tanda Auspitz, fenomena bercak lilin, dan ASTO positif. Pada pemeriksaan histopatologik didapatkan adanya parakeratosis dan mikroabses Munro. Terapi steroid topikal potensi tinggi selama 4 minggu menunjukkan perbaikan. Simpulan: Pada kasus ini diagnosis psoriasis gutata ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan pemeriksaan penunjang yang khas. Infeksi streptokokus diduga sebagai faktor pencetus berdasarkan hasil pemeriksaan ASTO. Terapi steroid topikal merupakan lini pertama untuk psoriasis ringan sampai sedang memperlihatkan perbaikan yang nyata.Kata kunci: psoriasis gutata, infeksi streptokokus


2017 ◽  
Vol 2 (2) ◽  
pp. 54-58
Author(s):  
Jonas A. Adalsteinsson ◽  
Yasmin Amir

Psoriasis and Crohn's disease are autoimmune diseases believed to share a similar pathogenesis. Ustekinumab is FDA-approved for treatment of psoriasis in 45 mg and 90 mg dosages and is undergoing phase III trials for Crohn's disease in higher dosages. Data on ustekinumab in guttate psoriasis (GP) are limited. We report the case of a 21-year-old female with Crohn's disease on adalimumab who developed severe, generalized GP 2 months after a streptococcal infection. Her GP did not regress after discontinuation of adalimumab. She began ustekinumab 45 mg every 12 weeks, which led to complete regression of her psoriasis. Due to persistent bowel symptoms, ustekinumab was increased to 135 mg every 8 weeks, with improvement. In this case, GP may have been related to recent streptococcal infection, or a complication of TNF-inhibitor therapy. Here, we show ustekinumab has potential as a therapeutic option for both GP and Crohn's disease.


2016 ◽  
Vol 7 (1) ◽  
pp. 51-52
Author(s):  
George Ferzli ◽  
Boris Bentsianov

ABSTRACT Psoriasis is a chronic dermatologic inflammatory disease characterized by scaly patches. Guttate psoriasis is characterized by numerous erythematous lesions measuring from 1 to 5 mm in diameter and most commonly found along the extremities and trunk. This type of psoriasis has been closely linked with preceding or concurrent streptococcal infections. There have been few studies demonstrating the role of tonsillectomy as a treatment option for guttate psoriasis. Adding to the literature of previously reported cases, we describe a case of a 28-year-old male with recurrent episodes of guttate psoriasis treated with tonsillectomy. How to cite this article Ferzli G, Bentsianov B. Dermatologic Manifestation of Streptococcal Infection: Tonsillectomy as a Treatment for Guttate Psoriasis. Int J Head Neck Surg 2016;7(1):51-52.


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