scholarly journals Developing a discrete choice experiment in Malawi: eliciting preferences for breast cancer early detection services

2015 ◽  
pp. 1459 ◽  
Author(s):  
Racquel Kohler ◽  
Clara Lee ◽  
Satish Gopal ◽  
Bryce Reeve ◽  
Stephanie Wheeler ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Breast Cancer Early Detection ◽  
Cancer Early Detection

scholarly journals Breast Cancer Knowledge, Behaviors, and Preferences in Malawi: Implications for Early Detection Interventions From a Discrete Choice Experiment

2017 ◽  
Vol 3 (5) ◽  
pp. 480-489 ◽  
Author(s):  
Racquel E. Kohler ◽  
Satish Gopal ◽  
Clara N. Lee ◽  
Bryan J. Weiner ◽  
Bryce B. Reeve ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Rural Areas ◽  
Choice Experiment ◽  
Multivariable Analysis ◽  
Breast Health ◽  
Cancer Knowledge ◽  
Breast Cancer Knowledge

Purpose Breast cancer is the most common female cancer in Africa and leading cause of death resulting from cancer; however, many countries lack early detection services. In Malawi, women are frequently diagnosed with large tumors after long symptomatic periods. Little is known about local cancer knowledge. Methods We administered a cross-sectional survey with a discrete choice experiment to a random sample in urban and rural areas of Lilongwe district. Bivariable and multivariable analyses determined factors associated with knowledge. Preference utilities for early detection interventions were estimated using a hierarchical Bayesian model in Sawtooth software. Results Of 213 women recruited, fewer than half were aware of breast cancer. In multivariable analysis, electricity at home and knowing someone with cancer increased the odds of awareness. Women were more knowledgeable about symptoms than treatment or risk factors; more than 60% erroneously believed local misconceptions. Seventeen percent were aware of breast self-examination, and 20% were aware of clinical breast examination (CBE); few reported either behavior. Common barriers included not knowing where to access CBE and transportation difficulties. Discrete choice experiment results indicated the detection strategy (breast health awareness, CBE, or both) was the most important attribute of an intervention, followed by the encounter setting and travel time. Conclusion Addressing misconceptions in health messages and engaging survivors to promote early detection may help improve breast cancer knowledge in Malawi. Program designs accounting for women’s preferences should provide breast health education and CBEs in convenient settings to address transportation barriers, particularly for women with low socioeconomic position.

scholarly journals Quality of Breast Cancer Early Detection Services Conducted by Well Woman Clinics in the District of Gampaha, Sri Lanka

2013 ◽  
Vol 14 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Palatiyana Vithanage Sajeewanie Chiranthika Vithana ◽  
M.A.Y. Ariyaratne ◽  
P.L. Jayawardana
Keyword(s):  
Breast Cancer ◽  
Sri Lanka ◽  
Early Detection ◽  
Breast Cancer Early Detection ◽  
Cancer Early Detection

scholarly journals Physician treatment of metastatic triple-negative breast cancer in the immuno-oncology era: a discrete choice experiment

2020 ◽  
Vol 16 (33) ◽  
pp. 2713-2722
Author(s):  
Bruce Feinberg ◽  
Skyler Hime ◽  
Jeff Wojtynek ◽  
Igoni Dokubo ◽  
Ajeet Gajra ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Therapy ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Triple Negative Breast Cancer ◽  
Choice Experiment ◽  
Triple Negative ◽  
Menopausal Status ◽  
Medical Oncologists ◽  
Clinical Scenarios

Aim: Guidelines list atezolizumab with nab-paclitaxel (ANP) as the preferred first-line (1L) therapy for metastatic triple-negative breast cancer (mTNBC) with PD-L1 expression ≥1%, but which clinical attributes impact ANP prescribing? Materials & methods: Medical oncologists participated in a discrete choice experiment (DCE) with four hypothetical mTNBC clinical scenarios to assess influences of: PD-L1 expression, menopausal status, prior adjuvant therapy and bulky liver metastases. Results: A total of 47% chose ANP in 1L irrespective of menopausal status, prior adjuvant therapy or tumor bulk. PD-L1 expression was the only attribute with a significant impact on ANP preference, with 69% choosing ANP for those with ≥1% expression versus only 26% for those with <1% (p < 0.00001). Conclusion: ANP choice for 1L mTNBC deviated from guidelines.

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