scholarly journals Long-Term Benefit and Withdrawal Effect of Statins After Percutaneous Coronary Intervention: A Nationwide Population-Based Cohort Study

2020 ◽  
Vol Volume 14 ◽  
pp. 717-724
Author(s):  
Hye Yun Jeong ◽  
So-Young Lee ◽  
Sang Hoon Kim ◽  
Jinkwon Kim
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Cohort Study ◽  
Coronary Intervention ◽  
Population Based ◽  
Withdrawal Effect ◽  
Percutaneous Coronary ◽  
Term Benefit

Short‐term safety and long‐term benefits of stent postdilation after primary percutaneous coronary intervention: Results of a cohort study

2019 ◽  
Vol 95 (7) ◽  
pp. 1249-1256
Author(s):  
Nasser Saadat ◽  
Seyedmohammad Saadatagah ◽  
Arash Aghajani Nargesi ◽  
Mohammad Alidoosti ◽  
Hamidreza Poorhosseini ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Cohort Study ◽  
Primary Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Short Term ◽  
Percutaneous Coronary

scholarly journals Prognostic utility of the combination of monocyte-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with NSTEMI after primary percutaneous coronary intervention: a retrospective cohort study

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e023459 ◽  
Author(s):  
Zeyuan Fan ◽  
Yang Li ◽  
Hanhua Ji ◽  
Xinwen Jian
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Cohort Study ◽  
Primary Percutaneous Coronary Intervention ◽  
Retrospective Cohort ◽  
Prognostic Value ◽  
Coronary Intervention ◽  
Free Survival ◽  
Lymphocyte Ratio ◽  
Percutaneous Coronary

ObjectivesThis study aimed to evaluate prognostic value of the combination of monocyte-to-lymphocyte ratio (MLR) with neutrophil-to-lymphocyte ratio (NLR) for predicting long-term major adverse cardiac events (MACE) in patients with non-ST elevated myocardial infarction (NSTEMI) who underwent primary percutaneous coronary intervention (PCI).DesignRetrospective cohort study.SettingCivil Aviation General Hospital, Beijing, China.Participants678 patients with NSTEMI undergoing primary PCI between July 2010 and July 2015 were enrolled.Main outcome measuresThe main outcomes were MACE. The cumulative MACE-free survival rates were calculated by Kaplan-Meier analysis and the independent predictors of MACE were assessed by Cox regression analysis.ResultsAccording to the cut-off values of MLR 0.36 and NLR 2.15, the study population was classified into four groups: low MLR + low NLR group (n=319), low MLR + high NLR group (n=126), high MLR + low NLR group (n=102) and high MLR + high NLR group (n=131). The high MLR + high NLR group had a lower MACE-free survival rate than the other three groups (p logrank <0.001). Both MLR (HR 2.128, 95% CI 1.458 to 3.105) and NLR (HR 1.925, 95% CI 1.385 to 2.676) were independent predictors of long-term MACE. Moreover, the patients in the high MLR + high NLR group had an HR of 4.055 (95% CI 2.550 to 6.448) for long-term MACE, with the low-MLR + low NLR group as reference. Comparisons of receiver operating characteristic curves revealed that the combination of MLR with NLR achieved better performance in differentiating long-term MACE, compared with MLR, NLR, high-sensitivity C reactive protein and brain natriuretic peptide alone, and had similar performance to all other pairwise combinations of the four biomarkers.ConclusionsElevated levels of MLR and NLR were independent predictors of long-term MACE in patients with NSTEMI. Moreover, the combination of MLR and NLR could improve the prognostic value in predicting long-term MACE.

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