scholarly journals Self-reported adherence and associated factors to isoniazid preventive therapy for latent tuberculosis among people living with HIV/AIDS at health centers in Gondar town, North West Ethiopia

2017 ◽  
Vol Volume 11 ◽  
pp. 743-749 ◽  
Author(s):  
Asnakew Achaw Ayele ◽  
Seyfe Asrade Atnafie ◽  
Demis Diriba Balcha ◽  
Asegedech Tsegaw Weredekal ◽  
Birhanu Alemayehu Woldegiorgis ◽  
...  
Keyword(s):  
Associated Factors ◽  
Latent Tuberculosis ◽  
Preventive Therapy ◽  
Health Centers ◽  
Isoniazid Preventive Therapy ◽  
People Living With Hiv ◽  
North West ◽  
Gondar Town ◽  
North West Ethiopia ◽  
Living With Hiv

scholarly journals Isoniazid Preventive Therapy Adherence and Associated Factors among HIV Positive Patients in Addis Ababa, Ethiopia

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Melaku Berhe ◽  
Meaza Demissie ◽  
Gezahegn Tesfaye
Keyword(s):  
Associated Factors ◽  
Addis Ababa ◽  
Latent Tuberculosis ◽  
Cross Sectional Study ◽  
Preventive Therapy ◽  
Health Centers ◽  
Isoniazid Preventive Therapy ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Living With Hiv

Tuberculosis coinfected with HIV constitutes a large proportion of patients in Ethiopia. Isoniazid preventive therapy (IPT) is recommended for the treatment of latent tuberculosis infection. However, the level of IPT adherence and associated factors among people living with HIV (PLHIV) have not been well explored. This study aimed to assess adherence to IPT and associated factors among PLHIV in Addis Ababa. Facility based cross-sectional study was conducted. The study was conducted in 10 health centers and 2 hospitals. Patients were consecutively recruited till the required sample size was obtained. From 406 PLHIV approached, a total of 381 patients on IPT were interviewed. Data were entered and analyzed using Epi-Info version 3.5 and SPSS version 16. The level of adherence to IPT was 89.5%. Patients who have taken isoniazid for ≥5 months were more likely to be adherent than those who took it for 1-2 months [AOR (95%CI) = 5.09 (1.41–18.36)]. Patients whose friends decide for them to start IPT were less likely to be adherent than others [AOR (95%CI) = 0.10 (0.01–0.82)]. The level of adherence to IPT in PLHIV was high. Counseling of patients who are in their first two months of therapy should be more strengthened. Strong Information Education Communication is essential to further enhance adherence.

scholarly journals Prevalence of Undernutrition and Associated Factors among Adult People Living with HIV/AIDS and on ART in Achefer District, North West Ethiopia: Cross-Sectional study

2020 ◽  
Author(s):  
Yosef Wasihun ◽  
Mengistu Yayehrad ◽  
Samuel Dagne ◽  
Yonatan Menber ◽  
Tadesse Awoke ◽  
...  
Keyword(s):  
Associated Factors ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Cross Sectional ◽  
North West ◽  
Under Nutrition ◽  
North West Ethiopia ◽  
Living With Hiv ◽  
Hiv Aids

Abstract Introduction: Human immunodeficiency virus/ Acquired immunodeficiency syndrome (HIV/AIDS) is one of the major public health Problem worldwide and its epidemic is occurring in populations where malnutrition is already endemic. Ethiopia is among the countries most affected by under nutrition and HIV epidemic in the region. The objective of this study was to determine the prevalence of under nutrition and associated factors among adult people living with HIV/AIDS and on ART in Achefer Woreda, North West Ethiopia.Methods and Materials: Institution based cross sectional study design was used and conducted from May 01–30/2015. Systematic random sampling technique was used to select the study subjects and the data was collected using clinical assessment, measurements and interviewer administered questionnaire. To identify independent predictors of under nutrition of adult people living with HIV/AIDS and on ART, we performed multivariable logistic regression analyses using SPSS version 20 with CI of 95% at p-value < 0. 05.Result: Three hundred fifty HIV/AIDS on ART patients were included in the study. The overall prevalence of under nutrition was 26.9% and females were most affected 57 (18.1%). Anti-retroviral treatment duration of 6-11months and 12–24 months (AOR = 4.72, 95% CI, 1.10-20.35) and (AOR = 6.93, 95% CI, 1.614–29.754) respectively, WHO Stage two and three (AOR = 3.01, 95% CI,1.061–8.534) and (AOR = 12.56, 95% CI, 4.27–36.99) respectively and dietary counseling (AOR = 0.20, 95% CI, .05-.78) were significantly associated with under nutrition.Conclusion and Recommendation: Undernutrition was high in PLWHA and on ART. ART duration, WHO clinical staging, presence of eating problem and dietary counselling were the predictors for under nutrition of HIV patients on ART. Only increasing access to ART can’t solve problem of under nutrition, therefore nutrition therapy and support, site expansion also as an accessory to the initiation of ART should be considered.

scholarly journals Uptake of Isoniazid Preventive Therapy (IPT) and Its Associated Factors among People Living with HIV (PLWHIV) in Kajiado County, Kenya

2020 ◽  
pp. 26-34
Author(s):  
Emmanuel Lemorijo Tobiko ◽  
Judith N. Waudo ◽  
Harun Kimani
Keyword(s):  
Associated Factors ◽  
Critical Role ◽  
Preventive Therapy ◽  
Isoniazid Preventive Therapy ◽  
Systematic Sampling ◽  
P Value ◽  
People Living With Hiv ◽  
Patient Knowledge ◽  
Living With Hiv

Isoniazid Preventive Therapy (IPT) involves use of isoniazid by People Living with HIV (PLWHIV) who have latent TB for a period not less than six months to prevent active TB infection. Despite the critical role of IPT in reducing HIV/TB co-infection related morbidity and deaths, not much has been done to examine why its full implementation has not been achieved and the probable solution. The objective of this study was to determine uptake of isoniazid preventive therapy and its associated factors among people living with HIV in Kajiado County, Kenya. Analytical Cross-sectional study was carried out in purposely selected four Hospitals. Two hundred and seventy two (272) study participants were recruited through systematic sampling with 100% response rate. Data were collected using structured questionnaires. Cross tabulation, bivariate and multivariate analysis was carried out to identify factors influencing IPT uptake. The study found out that IPT uptake was at 72%. Logistic regression analysis, established the existence of a significant positive association (p-value=0.000, βii=1.729) between patient knowledge among PLHIV and IPT uptake. A correlation analysis outcome shows the existence of a significant positive relationship (r=0.332, sig. =0.000) between patients knowledge and having ever used IPT at 0.01 level in a two tailed. The 72% of IPT uptake was sufficient. Patient knowledge factors had the highest influence on IPT amongst PLWHIV. The role of health care givers and health centers as IPT information disseminators and IPT knowledge source respectively, was invaluable in this study.

Provision of Isoniazid Preventive Therapy: The Experiences of People Living with HIV

2020 ◽  
Vol 21 (2) ◽  
Author(s):  
Keamogetse Selehelo ◽  
Lufuno Makhado ◽  
Karabo Angel Madiba
Keyword(s):  
South Africa ◽  
Health Centre ◽  
Preventive Therapy ◽  
Isoniazid Preventive Therapy ◽  
World Health ◽  
Hiv Care ◽  
People Living With Hiv ◽  
North West ◽  
Retention In Hiv Care ◽  
Living With Hiv

Isoniazid preventive therapy (IPT) is a strategy that has been proposed by the National Department of Health of South Africa and the World Health Organization for people living with HIV (PLWH) to prevent latent tuberculosis (TB) progressing to active TB. This research focused on exploring and describing experiences of PLWH regarding IPT provision in the Ngaka Modiri Molema district in the North West province of South Africa. A qualitative, exploratory, contextual and descriptive research design was used for this study. Semi-structured individual interviews were conducted to collect data from PLWH. The sample size consisted of 14 participants and data saturation was reached at participant 11. A thematic data analysis was employed in this study. The study consisted of 10 female participants and 4 male participants. Three main themes emerged during interviews, namely factors that facilitate IPT provision and uptake, factors that inhibit the adherence of patients to IPT, and strategies to improve provision or adherence. The provision of IPT at a community health centre in Ngaka Modiri Molema district municipality was reported to be satisfactorily although challenges were also marked. IPT must be available at all times to ensure the promotion of PLWH adherence, continuity of care and retention in HIV care. In addition, screening of PLWH for active TB disease before they can be initiated should be a priority. PLWH should be supported and followed up through the directly observed treatment, short-course strategy to promote adherence and this can also be facilitated through adherence social clubs.

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