scholarly journals Patient-centered care interventions for the management of alcohol use disorders: a systematic review of randomized controlled trials

2016 ◽  
Vol Volume 10 ◽  
pp. 1823-1845 ◽  
Author(s):  
P Barrio ◽  
Antoni Gual
2018 ◽  
Author(s):  
Joao Ricardo Nickenig Vissoci

BackgroundHarmful alcohol use leads to a large burden of disease and disability which disportionately impacts LMICs. The World Health Organization and the Lancet have issued calls for this burden to be addressed, but issues remain, primarily due to gaps in information. While a variety of interventions have been shown to be effective at reducing alcohol use in HICs, their efficacy in LMICs have yet to be assessed. This systematic review describes the current published literature on alcohol interventions in LMICs and conducts a meta analysis of clinical trials evaluating interventions to reduce alcohol use and harms in LMICs.MethodsIn accordance with PRISMA guidelines we searched the electronic databases Pubmed, EMBASE, Scopus,Web of Science, Cochrane, and Psych Info. Articles were eligible if they evaluated an intervention targeting alcohol-related harm in LMICs. After a reference and citation analysis, we conducted a quality assessment per PRISMA protocol. A meta-analysis was performed on the 39 randomized controlled trials that evaluated an alcohol-related outcome.ResultsOf the 3,801 articles from the literature search, 87 articles from 25 LMICs fit the eligibility and inclusion criteria. Of these studies, 39 randomized controlled trials were included in the meta-analysis. Nine of these studies focused specifically on medication, while the others focused on brief motivational intervention, brain stimulation, AUDIT-based brief interventions, WHO ASSIST-based interventions, group based education, basic screening and interventions, brief psychological or counseling, dyadic relapse prevention, group counseling, CBT, motivational + PTSD based interview, and health promotion/awareness. Conclusion Issues in determining feasible options specific to LMICs arise from unstandardized interventions, unequal geographic distribution of intervention implementation, and uncertain effectiveness over time. Current research shows that brain stimulation, psychotherapy, and brief motivational interviews have the potential to be effective in LMIC settings, but further feasibility testing and efforts to standardize results are necessary to accurately assess their effectiveness.


2021 ◽  
Author(s):  
Manasa Kolibylu Raghupathy ◽  
Bhamini Krishna Rao ◽  
Shubha R Nayak ◽  
Alicia J Spittle ◽  
Shradha S Parsekar

Abstract Background: Globally, very preterm birth is a health concern leading to various developmental difficulties such as poor motor and/or cognitive function. For infants born very preterm, Family-Centered Care (FCC) might promote developmental skills over the time in an appropriate enriched environment. The purpose of this study is to systematically review and assess the evidence of FCC interventions on the motor and neurobehavioral development in very preterm infants. Additionally, this review aims to determine the factors that might affect infant development.Methods: Systematic review will be carried out by including a) quasi-randomized controlled trials and randomized controlled trials b) of very preterm born infants (born < 32 weeks of gestation) and their primary caregivers will be included in the review c) who received FCC based interventions such as collaborative interaction between a healthcare professional and a parent, home program, home visits, and parent education and d) measure motor and neurobehavioral function. Electronic databases such as Scopus, PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, and PsycINFO will be searched using database-specific terms. Additionally, searches will be carried out in ProQuest, and references of included studies will be searched. Two review authors, independently, will conduct the screening, data extraction, and critical appraisal of included studies. If possible, a meta-analysis will be undertaken to assess the effect of the FCC on the motor and neurobehavior of premature infants.Conclusion: The review will provide insights regarding the effect of the FCC on preterm infants. This systematic review will guide the clinicians on the feasibility of practicing FCC that might support and promote the integration of parents into various rehabilitation settings.Systematic review registration: Protocol has been registered in PROSPERO on August 26, 2020.


2019 ◽  
Author(s):  
Ashley Clara Griffin ◽  
Zhaopeng Xing ◽  
Saif Khairat ◽  
Yue Wang ◽  
Stacy Bailey ◽  
...  

BACKGROUND Conversational agents have the potential to deliver patient-centered interventions that focus on goal setting, feedback, and education. However, little is known how these agents may be utilized to assist patients with chronic disease self-management. OBJECTIVE The objective of this study was to systematically review the literature to assess how conversational agents have been used to facilitate chronic disease self-management and to identify gaps in the evidence base. METHODS The systematic review utilized Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines across five databases. We included full-text journal articles or conference proceedings that contained primary research findings for text-based conversational agents focused on self-management for chronic diseases in adults. Two reviewers independently extracted information from the included studies, analyzed the data, grouped the studies into themes, and rated the quality of the studies. RESULTS 1,606 studies were identified, and 12 studies met inclusion criteria. There were five randomized controlled trials, five quasi-experimental studies, and two non-experimental studies. Studies were heterogeneous in design and many lacked methodological rigor. Participants mostly reported positive attitudes towards conversational agents, and there were improvements on the Patient Health Questionnaire (P<.05), Generalized Anxiety Disorder Scale (P=.004), Perceived Stress Scale (P=.048), Flourishing Scale (P=.032), and Overall Anxiety Severity and Impairment Scale (P<.05) between the conversational agent intervention and control groups in three randomized controlled trials. Major themes related to user perceptions were personalization, engagement, and social support. The majority of conversational agents were based upon theoretical grounding, but few studies reported using established design principles and no studies used heuristic evaluation. CONCLUSIONS Our findings suggest that conversational agents are acceptable and have the potential to support self-management particularly for mental health conditions. As this is an emerging area of research, efficacy of long-term use of conversational agents for chronic disease self-management is unknown but shows promise. Future studies should assess the characteristics of agents that may be most useful for self-management based on the patient’s clinical and sociodemographic characteristics, motivation, and preferences.


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Manasa Kolibylu Raghupathy ◽  
Bhamini Krishna Rao ◽  
Shubha R. Nayak ◽  
Alicia J. Spittle ◽  
Shradha S. Parsekar

Abstract Background Globally, very preterm birth is a health concern leading to various developmental difficulties such as poor motor and/or cognitive function. For infants born very preterm, family-centered care (FCC) might promote developmental skills over the time in an appropriate enriched environment. The purpose of this study is to systematically review and assess the evidence of FCC interventions on the motor and neurobehavioral development in very preterm infants. Additionally, this review aims to determine the factors that might affect infant development. Methods Systematic review will be carried out by including (a) quasi-randomized controlled trials and randomized controlled trials (b) of very preterm born infants (born < 32 weeks of gestation), and their primary caregivers will be included in the review (c) who received FCC-based interventions such as collaborative interaction between a healthcare professional and a parent, home program, home visits, and parent education, and (d) measure motor and neurobehavioral function. Electronic databases such as Scopus, PubMed, Embase, Cochrane Library, Web of Science, CINAHL, and PsycINFO will be searched using database-specific terms. Additionally, searches will be carried out in ProQuest, and references of included studies will be searched. Two review authors, independently, will conduct the screening, data extraction, and critical appraisal of included studies. If possible, a meta-analysis will be undertaken to assess the effect of the FCC on the motor and neurobehavior of premature infants. Conclusion The review will provide insights regarding the effect of the FCC on preterm infants. This systematic review will guide the clinicians on the feasibility of practicing FCC that might support and promote the integration of parents into various rehabilitation settings. Systematic review registration Protocol has been registered in PROSPERO on August 26, 2020.


JAMA ◽  
2014 ◽  
Vol 311 (18) ◽  
pp. 1861 ◽  
Author(s):  
Katharine A. Bradley ◽  
Daniel R. Kivlahan

2020 ◽  
Vol 20 (3) ◽  
pp. 1397-1406
Author(s):  
Sachi Tomokawa ◽  
Kimihiro Miyake ◽  
Takeshi Akiyama ◽  
Yuka Makino ◽  
Akihiro Nishio ◽  
...  

Background: Despite recognition of the risks of alcohol use and importance of prevention from an early age, the effectiveness of school-based interventions in Africa has not been clarified. Objective: We aimed to identify effective school-based alcohol use prevention interventions in Africa. Methods: We searched eight databases for peer-reviewed articles published until February 3, 2019 that reported on randomized controlled trials, cluster randomized controlled trials, controlled clinical trials, pre-post quasi-experimental stud- ies, cohort studies, and case-control studies. The full-texts of relevant studies were searched. Results: Four of 2797 papers met our eligibility criteria. All reported interventions targeted secondary school students in South Africa and were incorporated in the school curriculum. The interventions comprised multi-component activities with participatory and peer educational methods, and applied modified programs originally developed in the US. However, inter- vention effects were inconsistent among studies, although the interventions tended to have a positive effect on non-drinkers at baseline, with stronger effects in girls. Conclusion: Interventions had positive effects on students that were non-drinkers at baseline, especially girls. Although we could not find robust evidence that school-based interventions changed attitudes, frequency/quantity of drinking, and intentions to use alcohol, one intervention showed an increase in students’ alcohol refusal self-efficacy. Keywords: School-based preventive interventions; alcohol use; Africa; systematic review.


Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Zheng-Yii Lee ◽  
Cindy Sing Ling Yap ◽  
M. Shahnaz Hasan ◽  
Julia Patrick Engkasan ◽  
Mohd Yusof Barakatun-Nisak ◽  
...  

Abstract Background The optimal protein dose in critical illness is unknown. We aim to conduct a systematic review of randomized controlled trials (RCTs) to compare the effect of higher versus lower protein delivery (with similar energy delivery between groups) on clinical and patient-centered outcomes in critically ill patients. Methods We searched MEDLINE, EMBASE, CENTRAL and CINAHL from database inception through April 1, 2021.We included RCTs of (1) adult (age ≥ 18) critically ill patients that (2) compared higher vs lower protein with (3) similar energy intake between groups, and (4) reported clinical and/or patient-centered outcomes. We excluded studies on immunonutrition. Two authors screened and conducted quality assessment independently and in duplicate. Random-effect meta-analyses were conducted to estimate the pooled risk ratio (dichotomized outcomes) or mean difference (continuous outcomes). Results Nineteen RCTs were included (n = 1731). Sixteen studies used primarily the enteral route to deliver protein. Intervention was started within 72 h of ICU admission in sixteen studies. The intervention lasted between 3 and 28 days. In 11 studies that reported weight-based nutrition delivery, the pooled mean protein and energy received in higher and lower protein groups were 1.31 ± 0.48 vs 0.90 ± 0.30 g/kg and 19.9 ± 6.9 versus 20.1 ± 7.1 kcal/kg, respectively. Higher vs lower protein did not significantly affect overall mortality [risk ratio 0.91, 95% confidence interval (CI) 0.75–1.10, p = 0.34] or other clinical or patient-centered outcomes. In 5 small studies, higher protein significantly attenuated muscle loss (MD −3.44% per week, 95% CI −4.99 to −1.90; p < 0.0001). Conclusion In critically ill patients, a higher daily protein delivery was not associated with any improvement in clinical or patient-centered outcomes. Larger, and more definitive RCTs are needed to confirm the effect of muscle loss attenuation associated with higher protein delivery. PROSPERO registration number: CRD42021237530


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