scholarly journals Pediatric Kaposi sarcoma in context of the HIV epidemic in sub-Saharan Africa: current perspectives

2018 ◽  
Vol Volume 9 ◽  
pp. 35-46 ◽  
Author(s):  
Nader Kim El-Mallawany ◽  
Casey L McAtee ◽  
Liane R Campbell ◽  
Peter N Kazembe
Keyword(s):  
Kaposi Sarcoma ◽  
Sub Saharan Africa ◽  
Hiv Epidemic ◽  
Sub Saharan

Transmission of Kaposi sarcoma-associated herpesvirus in sub-Saharan Africa

AIDS ◽  
2008 ◽  
Vol 22 (4) ◽  
pp. 535-537 ◽  
Author(s):  
Sam M Mbulaiteye ◽  
James J Goedert
Keyword(s):  
Kaposi Sarcoma ◽  
Sub Saharan Africa ◽  
Sub Saharan

Impact of the HIV epidemic in sub-Saharan Africa on the pattern of HIV in the UK

AIDS ◽  
2003 ◽  
Vol 17 (11) ◽  
pp. 1683-1690 ◽  
Author(s):  
Katy Sinka ◽  
Janet Mortimer ◽  
Barry Evans ◽  
Dilys Morgan
Keyword(s):  
Sub Saharan Africa ◽  
Hiv Epidemic ◽  
Sub Saharan ◽  
The Uk

scholarly journals How does population viral load vary with the evolution of a large HIV epidemic in sub-Saharan Africa?

AIDS ◽  
2014 ◽  
Vol 28 (6) ◽  
pp. 927-929 ◽  
Author(s):  
Laith J. Abu-Raddad ◽  
Susanne F. Awad
Keyword(s):  
Viral Load ◽  
Sub Saharan Africa ◽  
Hiv Epidemic ◽  
Sub Saharan

scholarly journals Employers’ responses to the HIV epidemic in sub-Saharan Africa: Revisiting the evidence

2018 ◽  
Vol 37 (2) ◽  
pp. 245-259 ◽  
Author(s):  
Kevin Deane ◽  
Sara Stevano ◽  
Deborah Johnston
Keyword(s):  
Sub Saharan Africa ◽  
Hiv Epidemic ◽  
Sub Saharan

scholarly journals Viral and immunological markers of HIV-associated Kaposi sarcoma recurrence

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254177
Author(s):  
Owen Ngalamika ◽  
Marie Claire Mukasine ◽  
Musonda Kawimbe ◽  
Faheema Vally
Keyword(s):  
Kaposi Sarcoma ◽  
Sub Saharan Africa ◽  
Sustained Remission ◽  
Hiv Viral Load ◽  
Factors Associated ◽  
Viral Loads ◽  
Cytokines And Chemokines ◽  
Immunological Markers ◽  
Sub Saharan

Kaposi sarcoma (KS) is an AIDS-defining angio-proliferative malignancy highly prevalent in Sub-Saharan Africa. The main objective of this study was to determine the factors associated with recurrence of HIV-associated KS. We recruited a cohort of individuals on antiretroviral therapy who were in remission for HIV-associated KS after undergoing cytotoxic cancer chemotherapy. Collected variables included sociodemographic and clinical parameters, cytokines and chemokines, HIV viral loads, and CD4 counts. Compared to individuals who had KS recurrence, IL-5 was significantly higher at time of follow-up in individuals who had sustained remission (22.7pg/ml vs. 2.4pg/ml; p = 0.02); IL-6 was significantly higher at baseline and time of follow-up in individuals who had sustained remission, (18.4pg/ml vs. 0pg/ml; p = 0.01) and (18.0pg/ml vs. 0.18pg/ml; p = 0.03) respectively; IP-10 was significantly lower at baseline and at time of follow-up in individuals who had sustained remission, (534pg/ml vs. 920pg/ml; p = 0.04) and (446pg/ml vs.1098pg/ml; p = 0.01) respectively; while HIV viral load was significantly lower at baseline and at time of follow-up in individuals who had sustained remission, (0copies/ml vs. 113copies/ml; p = 0.004) and (0copies/ml vs. 152copies/ml; p = 0.025) respectively. Plasma levels of IL-5, IL-6, and IP-10 are associated with recurrence of HIV-associated KS, while persistently detectable HIV viral loads increase the risk of KS recurrence.

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