scholarly journals Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335

2020 ◽  
Vol Volume 13 ◽  
pp. 2357-2367 ◽  
Author(s):  
Facai Yang ◽  
Zhaohui Tang ◽  
Anqi Duan ◽  
Bin Yi ◽  
Ningjia Shen ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Long noncoding RNA SOX21‐AS1 promotes cervical cancer progression by competitively sponging miR‐7/VDAC1

2019 ◽  
Vol 234 (10) ◽  
pp. 17494-17504 ◽  
Author(s):  
Xiaoyan Zhang ◽  
Xianlan Zhao ◽  
Yan Li ◽  
Yan Zhou ◽  
Zhenyu Zhang
Keyword(s):  
Cervical Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Long noncoding RNA MAGI2-AS3 regulates CCDC19 expression by sponging miR-15b-5p and suppresses bladder cancer progression

2018 ◽  
Vol 507 (1-4) ◽  
pp. 231-235 ◽  
Author(s):  
Feng Wang ◽  
Yanwen Zu ◽  
Shibin Zhu ◽  
Yu Yang ◽  
Weiping Huang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3–c-Myc axis

Oncogene ◽  
2020 ◽  
Vol 39 (19) ◽  
pp. 3926-3938 ◽  
Author(s):  
Qingzu Gao ◽  
Rui Zhou ◽  
Yuan Meng ◽  
Rongfei Duan ◽  
Ling Wu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Colorectal Cancer Progression

Long noncoding RNA SNHG12 modulated by human papillomavirus 16 E6/E7 promotes cervical cancer progression via ERK/Slug pathway

2020 ◽  
Vol 235 (11) ◽  
pp. 7911-7922 ◽  
Author(s):  
Shu‐Yu Lai ◽  
Hong‐Mei Guan ◽  
Jie Liu ◽  
Li‐Jun Huang ◽  
Xiao‐Lin Hu ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Human Papillomavirus 16

scholarly journals ESR1-Stabilizing Long Noncoding RNA TMPO-AS1 Promotes Hormone-Refractory Breast Cancer Progression

2019 ◽  
Vol 39 (23) ◽  
Author(s):  
Yuichi Mitobe ◽  
Kazuhiro Ikeda ◽  
Takashi Suzuki ◽  
Kiyoshi Takagi ◽  
Hidetaka Kawabata ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Patients ◽  
Endocrine Therapy ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Breast Cancer Patients ◽  
Er Positive ◽  
Positive Breast Cancer

ABSTRACT Acquired endocrine therapy resistance is a significant clinical problem for breast cancer patients. In recent years, increasing attention has been paid to long noncoding RNA (lncRNA) as a critical modulator for cancer progression. Based on RNA-sequencing data of breast invasive carcinomas in The Cancer Genome Atlas database, we identified thymopoietin antisense transcript 1 (TMPO-AS1) as a functional lncRNA that significantly correlates with proliferative biomarkers. TMPO-AS1 positivity analyzed by in situ hybridization significantly correlates with poor prognosis of breast cancer patients. TMPO-AS1 expression was upregulated in endocrine therapy-resistant MCF-7 cells compared with levels in parental cells and was estrogen inducible. Gain and loss of TMPO-AS1 experiments showed that TMPO-AS1 promotes the proliferation and viability of estrogen receptor (ER)-positive breast cancer cells in vitro and in vivo. Global expression analysis using a microarray demonstrated that TMPO-AS1 is closely associated with the estrogen signaling pathway. TMPO-AS1 could positively regulate estrogen receptor 1 (ESR1) mRNA expression by stabilizing ESR1 mRNA through interaction with ESR1 mRNA. Enhanced expression of ESR1 mRNA by TMPO-AS1 could play a critical role in the proliferation of ER-positive breast cancer. Our findings provide a new insight into the understanding of molecular mechanisms underlying hormone-dependent breast cancer progression and endocrine resistance.

Long noncoding RNA DLX6-AS1 promotes breast cancer progression via miR-505-3p/RUNX2 axis

2019 ◽  
Vol 865 ◽  
pp. 172778 ◽  
Author(s):  
Ping Zhao ◽  
Haitao Guan ◽  
Zhijun Dai ◽  
Yuguang Ma ◽  
Yang Zhao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Breast Cancer Progression
Sign in / Sign up

Export Citation Format

Share Document