scholarly journals Helicobacter pylori CagA Protein Attenuates 5-Fu Sensitivity of Gastric Cancer Cells Through Upregulating Cellular Glucose Metabolism

2020 ◽  
Vol Volume 13 ◽  
pp. 6339-6349
Author(s):  
Sujie Gao ◽  
Defeng Song ◽  
Yiting Liu ◽  
Hongwei Yan ◽  
Xuebo Chen
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Glucose Metabolism ◽  
Cancer Cells ◽  
Gastric Cancer Cells ◽  
Caga Protein

scholarly journals Helicobacter pylori CagA protein activates Akt and attenuates chemotherapeutics-induced apoptosis in gastric cancer cells

Oncotarget ◽  
2017 ◽  
Vol 8 (69) ◽  
pp. 113460-113471 ◽  
Author(s):  
Keng-Hsueh Lan ◽  
Wei-Ping Lee ◽  
Yu-Shan Wang ◽  
Shi-Xian Liao ◽  
Keng-Hsin Lan
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cancer Cells ◽  
Gastric Cancer Cells ◽  
Caga Protein ◽  
Induced Apoptosis

Distinct mechanism of helicobacter pylori-mediated NF-κB activation between gastric cancer cells, MKN45 and monocystic cells, THP-1

2001 ◽  
Vol 120 (5) ◽  
pp. A82-A82 ◽  
Author(s):  
S MAEDA ◽  
Y MITSUNO ◽  
Y HIRATA ◽  
M AKANUMA ◽  
H YOSHIDA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cancer Cells ◽  
Gastric Cancer Cells ◽  
Distinct Mechanism

Abstract 37: Effect of glucose metabolism-related enzymes on the proliferation of gastric cancer cells in hypoxic microenvironment

2016 ◽  
Author(s):  
Kishu Kitayama ◽  
Masakazu Yashiro ◽  
Tamami Morisaki ◽  
Go Masuda ◽  
Hiroakai Kasashima ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Glucose Metabolism ◽  
Cancer Cells ◽  
Gastric Cancer Cells ◽  
Effect Of Glucose

In vitro sensitivity of human gastric cancer cells (HGC‐27) to Helicobacter pylori cytotoxin

2003 ◽  
Vol 38 (12) ◽  
pp. 1228-1234 ◽  
Author(s):  
A. Pessina ◽  
M. Bayo ◽  
C. Croera ◽  
F. Meringolo ◽  
M. G. Neri ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cancer Cells ◽  
Human Gastric Cancer ◽  
Gastric Cancer Cells ◽  
In Vitro Sensitivity

T1183 Activation of Wnt and NF-kB Regulated Gene CK2 in Helicobacter pylori-Activated Gastric Cancer Cells

2010 ◽  
Vol 138 (5) ◽  
pp. S-506 ◽  
Author(s):  
Yeo Song Lee ◽  
Sung hwa Sohn ◽  
Kyung-Ran Park ◽  
Sang Hun Lee ◽  
Hyun ki Kim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cancer Cells ◽  
Gastric Cancer Cells

scholarly journals The Expression of Bcl-2 and BID in Gastric Cancer Cells

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Mariusz Gryko ◽  
Anna Pryczynicz ◽  
Konrad Zareba ◽  
Bogusław Kędra ◽  
Andrzej Kemona ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Lymph Node ◽  
Cancer Cells ◽  
Clinicopathological Parameters ◽  
Gastric Cancer Cells ◽  
Study Objective ◽  
Node Metastases ◽  
Local Lymph Node ◽  
T4 Gastric Cancer

Background.Bcl-2 and BID play a major role in the process of apoptosis and their dysfunction underlies carcinogenesis. The study objective was to assess the expression of Bcl-2 and BID in gastric cancer cells in correlation with chosen clinicopathological parameters, presence ofHelicobacter pyloriinfection, and patients’ survival.Materials and Methods.The study involved 88 patients operated on for gastric cancer. The expressions of Bcl-2 and BID were determined immunohistochemically.Results.Positive Bcl-2 expression was found in 55.7% and, BID in 53.6% of patients. The Bcl-2 expression correlated with stage pT3 and T4 gastric cancerP<0.05, with the intestinal type according to LaurenP<0.001, ulcerated type according to Bormann’s classificationP<0.01, and with local lymph node metastasesP<0.05.Conclusion.The Bcl-2 protein plays a key role in the process of gastric cancer formation and is associated with the growth of definite types of gastric cancer.

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