scholarly journals Conformance Assessment of PD-L1 Expression Between Primary Tumour and Nodal Metastases in Non-Small-Cell Lung Cancer

2019 ◽  
Vol Volume 12 ◽  
pp. 11541-11547
Author(s):  
Haipeng Xu ◽  
Xueyan Chen ◽  
Dong Lin ◽  
Jing Zhang ◽  
Chao Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumour ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases

Lung Cancer ◽  
2019 ◽  
Vol 127 ◽  
pp. S25 ◽  
Author(s):  
A. Haragan ◽  
J. Gosney ◽  
J.K. Field ◽  
M. Davies ◽  
C. Escriu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumour ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung

scholarly journals Clinical Predictors of Nodal Metastases in Peripherally Clinical T1a N0 Non-Small Cell Lung Cancer

2017 ◽  
Vol 104 (4) ◽  
pp. 1153-1158 ◽  
Author(s):  
Galal Ghaly ◽  
Mohamed Rahouma ◽  
Mohamed K. Kamel ◽  
Abu Nasar ◽  
Sebron Harrison ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung ◽  
Clinical Predictors

92 POSTER Skip mediastinal nodal metastases in the IIIA/N2 non-small cell lung cancer

2006 ◽  
Vol 32 ◽  
pp. S28-S29
Author(s):  
N. Ilic ◽  
A. Petricevic ◽  
N. Frleta Ilic ◽  
D. Arar ◽  
J. Banovic ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung

scholarly journals Prediction of microscopic metastases in patients with metachronous oligo-metastases after curative treatment of Non-Small Cell Lung Cancer

2019 ◽  
Author(s):  
H.B. Wolff ◽  
L. Alberts ◽  
E.A. Kastelijn ◽  
N.E. Verstegen ◽  
S.Y. El Sharouni ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Primary Tumour ◽  
Small Cell ◽  
Small Cell Lung ◽  
Curative Intent ◽  
Patient Level Data ◽  
Patient Level ◽  
Level Data

AbstractMetachronous oligo-metastatic disease is variably defined as one to five metastases detected after a disease-free interval and treatment of the primary tumour with curative intent. Oligo-metastases in non-small cell lung cancer (NSCLC) are often treated with curative intent. However additional metastases are often detected later in time, and 5-year survival is low. Burdensome surgical treatment in patients with undetected metastases may be avoided if patients with high versus low-risk of undetected metastases can be separated.Because there is no clinical data on undetected metastases available, a microsimulation-model of the development and detection of metastases in 100.000 stage I NSCLC patients with a controlled primary tumour was constructed. The model uses data from the literature as well as patient-level data. Calibration was used for unobservable model parameters. Metastases can be detected by a scheduled scan, or an unplanned scan when the patient develops symptoms. The observable information at time of detection is used to identify subgroups of patients with different risk of undetectable metastases. We identified size and number of detected oligo-metastases, as well as presence of symptoms to be the most important risk predictors. Based on these predictors, patients could be divided into a low-risk and a high-risk group having a model-based predicted probability of 8.1% and 89.3% to have undetected metastases, respectively.Currently, the model is based on a synthesis of literature data and individual patient-level data that was not collected for the purpose of this study. Optimisation and validation of the model is necessary to allow clinical usability. We describe the type of data that needs to be collected to update our model, as well as the design of such validation study.

scholarly journals Skip Mediastinal Nodal Metastases in the IIIa/N2 Non-Small Cell Lung Cancer

2007 ◽  
Vol 2 (11) ◽  
pp. 1018-1021 ◽  
Author(s):  
Nenad Ilic ◽  
Ante Petricevic ◽  
Dragan Arar ◽  
Slavica Kotarac ◽  
Josip Banovic ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung

Extranodal extension of nodal metastases is a poor prognostic moderator in non-small cell lung cancer: a meta-analysis

2018 ◽  
Vol 472 (6) ◽  
pp. 939-947 ◽  
Author(s):  
Claudio Luchini ◽  
Nicola Veronese ◽  
Alessia Nottegar ◽  
Monica Cheng ◽  
Takuma Kaneko ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Meta Analysis ◽  
Small Cell ◽  
Nodal Metastases ◽  
Small Cell Lung ◽  
Extranodal Extension

Unfavorable Prognosis of Patients With Stage II Non-small Cell Lung Cancer Associated With Macroscopic Nodal Metastases

CHEST Journal ◽  
1999 ◽  
Vol 116 (1) ◽  
pp. 144-149 ◽  
Author(s):  
Ichiro Yoshino ◽  
Ryoichi Nakanishi ◽  
Toshihiro Osaki ◽  
Mitsuhiro Takenoyama ◽  
Satoshi Taga ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Stage Ii ◽  
Nodal Metastases ◽  
Small Cell Lung
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