scholarly journals Successful long-term treatment of non–small cell lung cancer positive for RET rearrangement with pemetrexed

2019 ◽  
Vol Volume 12 ◽  
pp. 5355-5358
Author(s):  
Masayuki Takeda ◽  
Kazuko Sakai ◽  
Kazuto Nishio ◽  
Kazuhiko Nakagawa
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Small Cell Lung ◽  
Long Term Treatment

Efficacy of platinum rechallenge chemotherapy in sensitive relapsed small cell lung cancer after a long-term treatment-free interval.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e18554-e18554
Author(s):  
Yasushi Murakami ◽  
Hideo Saka ◽  
Masahide Oki ◽  
Chiyoe Kitagawa ◽  
Yoshihito Kogure
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Small Cell Lung ◽  
Free Interval ◽  
Long Term Treatment

scholarly journals RESECTION OF TRACHEAL BIFURCATION IN TREATMENT OF NON-SMALL CELL LUNG CANCER (LITERATURE REVIEW)

2018 ◽  
Vol 17 (5) ◽  
pp. 94-105 ◽  
Author(s):  
I. A. Dadyev ◽  
М. M. Davydov ◽  
A. K. Chekini ◽  
M. A. Anisimov ◽  
S. S. Gerasimov ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Anesthetic Techniques ◽  
Small Cell Lung ◽  
Extensive Experience ◽  
Long Term Treatment ◽  
Tracheal Bifurcation

Over the past few years, significant advances in surgical and anesthetic techniques as well as appropriate selection of patients have led to an improvement in the immediate and long-term treatment outcomes in patients with non-small cell lung cancer with involvement of tracheal bifurcation. In accordance with the current selection criteria, patients with contralateral lymph node metastases (lung root, aortic window, paratracheal area) require chemotherapy or chemoradiotherapy with subsequent estimation of follow-up and treatment strategy. Surgeries with resection of tracheobronchial bifurcation are considered technically complicated, and they should be performed in carefully selected lung cancer patients and only in specialized centers with extensive experience. It allows the incidence of intra-and postoperative complications to be significantly reduced.

Cytogenetic Findings in Primary Non-Small Cell Lung Cancer

1994 ◽  
Vol 80 (2) ◽  
pp. 151-156
Author(s):  
Elvira D'Alessandro ◽  
Maria Luisa Lo Re ◽  
Roberto Crisci ◽  
Claudio Ligas ◽  
Giorgio Furio Coloni
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Chromosome Loss ◽  
Small Cell Lung ◽  
Primary Nsclc ◽  
Cytogenetic Analyses ◽  
Triploid Clone

Non-small cell lung cancer (NSCLC) shows a complex cytogenetic heterogeneity and up to now no particular chromosomal aberration seems to characterize its malignant evolution. We therefore performed cytogenetic analyses of 20 primary NSCLC, 8 adenocarcinomas and 12 squamous cell carcinomas on direct preparations or short-term cultures. Only 1 case was analyzed after long-term culture. Results were obtained from 11 samples and clonal rearrangements were found in 3 cases, a diploid and a near-triploid clone with several aberrations such as i (9q), rob (14; 15) and rob (21; 21) in 1 case, a near-triploid clone in 1 case, and Y chromosome loss in 1 case. Other aberrations found were sporadic, but + 7 aneuploidy and translocations involving 1p were detected in 2 and 3 samples respectively. Although to date it has been very difficult to recognize primary changes in NSCLC, nevertheless a literature review and our results indicate that i(9q) and robertsonian translocations are relevant findings.

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