scholarly journals Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-κB pathway

2017 ◽  
Vol Volume 10 ◽  
pp. 5843-5853 ◽  
Author(s):  
Nan Cheng ◽  
Yang Guo
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Nf Kappa B

scholarly journals Long noncoding RNA UCA1 promotes the proliferation, invasion, and migration of nasopharyngeal carcinoma cells via modulation of miR-145

2018 ◽  
Vol Volume 11 ◽  
pp. 7483-7492 ◽  
Author(s):  
Jing Wu ◽  
Mingyu Du ◽  
Qian Zhang ◽  
Wenjun Zhang ◽  
Yanxin Fan ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Carcinoma Cells ◽  
Invasion And Migration ◽  
And Migration

scholarly journals Long Noncoding RNA DANCR Regulates Cell Proliferation by Stabilizing SOX2 mRNA in Nasopharyngeal Carcinoma

2020 ◽  
Vol 190 (12) ◽  
pp. 2343-2354
Author(s):  
Qiang Li ◽  
Yiming Jiang ◽  
Guansheng Zhong ◽  
Yanwei Lu ◽  
Tao Song ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna

scholarly journals Long noncoding RNA SMAD5‐AS1 acts as a microRNA‐106a‐5p sponge to promote epithelial mesenchymal transition in nasopharyngeal carcinoma

2019 ◽  
Vol 33 (11) ◽  
pp. 12915-12928 ◽  
Author(s):  
Ying‐Juan Zheng ◽  
Jing‐Yi Zhao ◽  
Tian‐Song Liang ◽  
Ping Wang ◽  
Juan Wang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Epithelial Mesenchymal Transition ◽  
Mesenchymal Transition

scholarly journals Long Noncoding RNA OIP5-AS1 Promotes the Disease Progression in Nasopharyngeal Carcinoma by Targeting miR-203

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Jian Tang ◽  
Chengxiao Fu ◽  
Yanwen Li ◽  
Shuangqin Chen ◽  
Xiaoxin Jiang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Migration And Invasion ◽  
Functional Link ◽  
Interacting Protein ◽  
Promising Target ◽  
Precise Role

Nasopharyngeal carcinoma (NPC) is a kind of malignancy generated from the nasopharyngeal epithelium. Recently, long noncoding RNA (lncRNA) has been shown to be involved in the regulation of many signaling pathways and is closely associated with carcinogenesis and tumor progression. However, the precise role of lncRNA Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1) in NPC is not well understood. Here, we find that OIP5-AS1 is overexpressed in NPC patient specimens and NPC cell lines. Further investigations reveal that knockdown of OIP5-AS1 significantly inhibits the proliferation, migration, and invasion and accelerates the apoptosis of NPC cells in vitro. Consistent with these findings, NPC progression is significantly slowed in mice when OIP5-AS1 is knocked down. Interestingly, there is a functional link between OIP5-AS1 and microRNA-203 (miR-203), a tumor suppressor, in NPC cells. In conclusion, our data demonstrate that OIP5-AS1 plays an important role in the development and progression of NPC by targeting miR-203 and therefore provide a promising target for the treatment of NPC.

Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3

2019 ◽  
Vol 79 (18) ◽  
pp. 4612-4626 ◽  
Author(s):  
Zi-Qi Zheng ◽  
Zhi-Xuan Li ◽  
Guan-Qun Zhou ◽  
Li Lin ◽  
Lu-Lu Zhang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna

scholarly journals The role of long noncoding RNA-LET in cell proliferation and invasion of nasopharyngeal carcinoma and its mechanism

2017 ◽  
Vol Volume 10 ◽  
pp. 2769-2778 ◽  
Author(s):  
Lei Chen ◽  
Lingling Sun ◽  
Lei Dong ◽  
Peng Cui ◽  
Ziwei Xia ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Nasopharyngeal Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Proliferation And Invasion
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