scholarly journals Effects of insulin analogs and glucagon-like peptide-1 receptor agonists on proliferation and cellular energy metabolism in papillary thyroid cancer

2017 ◽  
Vol Volume 10 ◽  
pp. 5621-5631 ◽  
Author(s):  
Liang He ◽  
Siliang Zhang ◽  
Xiaowen Zhang ◽  
Rui Liu ◽  
Haixia Guan ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Energy Metabolism ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Insulin Analogs ◽  
Cellular Energy ◽  
Receptor Agonists ◽  
Cellular Energy Metabolism ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

scholarly journals Initiating Titratable Fixed-Ratio Combinations of Basal Insulin Analogs and Glucagon-Like Peptide-1 Receptor Agonists: What You Need to Know

2018 ◽  
Vol 36 (2) ◽  
pp. 174-182 ◽  
Author(s):  
Neil Skolnik ◽  
Debbie Hinnen ◽  
Yan Kiriakov ◽  
Melissa L. Magwire ◽  
John R. White
Keyword(s):  
Basal Insulin ◽  
Fixed Ratio ◽  
Insulin Analogs ◽  
Receptor Agonists ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

scholarly journals Reprogramming of Energy Metabolism: Increased Expression and Roles of Pyruvate Carboxylase in Papillary Thyroid Cancer

Thyroid ◽  
2019 ◽  
Vol 29 (6) ◽  
pp. 845-857 ◽  
Author(s):  
Aurélie Strickaert ◽  
Cyril Corbet ◽  
Selim-Alex Spinette ◽  
Ligia Craciun ◽  
Geneviève Dom ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Energy Metabolism ◽  
Papillary Thyroid Cancer ◽  
Pyruvate Carboxylase ◽  
Papillary Thyroid

scholarly journals Insights into a possible role of glucagon-like peptide-1 receptor agonists in the treatment of depression

2021 ◽  
Author(s):  
Jan Detka ◽  
Katarzyna Głombik
Keyword(s):  
Nervous System ◽  
Energy Metabolism ◽  
Antidepressant Drugs ◽  
Modern Society ◽  
Scientific Data ◽  
Receptor Agonists ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
The Stability

AbstractDepression is a highly prevalent mood disorder and one of the major health concerns in modern society. Moreover, it is characterized by a high prevalence of coexistence with many other diseases including metabolic disorders such as type 2 diabetes mellitus (T2DM) and obesity. Currently used antidepressant drugs, which mostly target brain monoaminergic neurotransmission, have limited clinical efficacy. Although the etiology of depression has not been fully elucidated, current scientific data emphasize the role of neurotrophic factors deficiencies, disturbed homeostasis between the nervous system and the immune and endocrine systems, as well as disturbances in brain energy metabolism and dysfunctions in the gut-brain axis as important factors in the pathogenesis of this neuropsychiatric disorder. Therefore, therapeutic options that could work in a way other than classic antidepressants are being sought to increase the effectiveness of the treatment. Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system. This review article discusses the potential antidepressant effects of GLP-1RAs, especially in the context of their action on the processes related to neuroprotection, inflammation, stress response, energy metabolism, gut-brain crosstalk and the stability of the gut microbiota. Graphic abstract

Abstract #1086: Patient Experience with Severe Low Energy Following Total Thyroidectomy for Papillary Thyroid Cancer

2017 ◽  
Vol 23 ◽  
pp. 258
Author(s):  
Elizabeth Wendt ◽  
Maria Bates ◽  
Reese Randle ◽  
Jason Orne ◽  
Cameron Macdonald ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Total Thyroidectomy ◽  
Papillary Thyroid Cancer ◽  
Patient Experience ◽  
Low Energy ◽  
Papillary Thyroid
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