scholarly journals Association of GEMIN4 gene polymorphism and the risk of cancer: a meta-analysis

2017 ◽  
Vol Volume 10 ◽  
pp. 5263-5271
Author(s):  
Nan Wu ◽  
Xiaowei Zhang ◽  
Jinlong Tian ◽  
Shuang Yu ◽  
Ying Qiao
Keyword(s):  
Gene Polymorphism ◽  
Meta Analysis ◽  
Risk Of Cancer ◽  
Em Gene

scholarly journals ACE gene polymorphism is associated with COPD and COPD with pulmonary hypertension: a meta-analysis

2018 ◽  
Vol Volume 13 ◽  
pp. 2435-2446 ◽  
Author(s):  
Yao Ma ◽  
Xiang Tong ◽  
Ying Liu ◽  
Sitong Liu ◽  
Hai Xiong ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Gene Polymorphism ◽  
Meta Analysis ◽  
Em Gene

scholarly journals LAPTM4B gene polymorphism augments the risk of cancer: Evidence from an updated meta-analysis

2018 ◽  
Vol 22 (12) ◽  
pp. 6396-6400 ◽  
Author(s):  
Mohammad Hashemi ◽  
Gholamreza Bahari ◽  
Farhad Tabasi ◽  
Jarosław Markowski ◽  
Andrzej Małecki ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Meta Analysis ◽  
Risk Of Cancer

scholarly journals Association between the IL-6 gene polymorphism and tuberculosis risk: a meta-analysis

2017 ◽  
Vol Volume 10 ◽  
pp. 445-454 ◽  
Author(s):  
Hao Wang ◽  
Caishuang Pang ◽  
Ni Zeng ◽  
Chun Wan ◽  
Yongchun Shen ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Meta Analysis ◽  
Em Gene ◽  
Tuberculosis Risk

scholarly journals Association of the PTEN IVS4 (rs3830675) Gene Polymorphism with Reduced Risk of Cancer: Evidence from a Meta-analysis

2015 ◽  
Vol 16 (3) ◽  
pp. 897-902 ◽  
Author(s):  
Raju K. Mandal ◽  
Naseem Akhter ◽  
Mohammad Irshad ◽  
Aditya K. Panda ◽  
Arif Ali ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Meta Analysis ◽  
Risk Of Cancer ◽  
Reduced Risk

Association between ALDH2 Gene Polymorphism and Late-onset Alzheimer Disease: An Up-to-date Meta-analysis

2020 ◽  
Vol 17 (2) ◽  
pp. 105-111
Author(s):  
Haitao Liu ◽  
Wei Ge ◽  
Wei Chen ◽  
Xue Kong ◽  
Weiming Jian ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Large Scale ◽  
Late Onset ◽  
Meta Analysis ◽  
Case Control ◽  
Cochrane Library ◽  
Positive Trend ◽  
Case Control Studies ◽  
China National Knowledge Infrastructure ◽  
Aldh2 Gene

Objectives: Previous case-control studies have focused on the relationship between ALDH2 gene polymorphism and late-onset Alzheimer's Disease (LOAD), but no definite unified conclusion has been reached. Therefore, the correlation between ALDH2 Glu504Lys polymorphism and LOAD remains controversial. To analyze the correlation between ALDH2 polymorphism and the risk of LOAD, we implemented this up-to-date meta-analysis to assess the probable association. Methods: Studies were searched through China National Knowledge Infrastructure (CNKI), VIP Database for Chinese Technical Periodicals, China Biology Medicine, PubMed, Cochrane Library, Clinical- Trials.gov, Embase, and MEDLINE from January 1, 1994 to December 31, 2018, without any restrictions on language and ethnicity. Results: Five studies of 1057 LOAD patients and 1136 healthy controls met our criteria for the analysis. Statistically, the ALDH2 GA/AA genotype was not linked with raising LOAD risk (odds ratio (OR) = 1.48, 95% confidence interval (CI) = 0.96-2.28, p = 0.07). In subgroup analysis, the phenomenon that men with ALDH2*2 had higher risk for LOAD (OR = 1.72, 95%CI = 1.10-2.67, p = 0.02) was observed. Conclusions: This study comprehends only five existing case-control studies and the result is negative. The positive trend might appear when the sample size is enlarged. In the future, more large-scale casecontrol or cohort studies should be done to enhance the association between ALDH2 polymorphism and AD or other neurodegenerative diseases.

Adverse childhood experiences and risk of cancer during adulthood: A systematic review and meta-analysis

2021 ◽  
Vol 117 ◽  
pp. 105088
Author(s):  
Zhao Hu ◽  
Atipatsa Chiwanda Kaminga ◽  
Jun Yang ◽  
Jiefeng Liu ◽  
Huilan Xu
Keyword(s):  
Systematic Review ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Risk Of Cancer

scholarly journals Health Risks of Structural Firefighters from Exposure to Polycyclic Aromatic Hydrocarbons: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (8) ◽  
pp. 4209
Author(s):  
Jooyeon Hwang ◽  
Chao Xu ◽  
Robert J. Agnew ◽  
Shari Clifton ◽  
Tara R. Malone
Keyword(s):  
Risk Factors ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Meta Analysis ◽  
Occupational Exposures ◽  
Fire Smoke ◽  
Polycyclic Aromatic ◽  
Pah Exposure ◽  
In Fire ◽  
Risk Of Cancer

Firefighters have an elevated risk of cancer, which is suspected to be caused by occupational and environmental exposure to fire smoke. Among many substances from fire smoke contaminants, one potential source of toxic exposure is polycyclic aromatic hydrocarbons (PAH). The goal of this paper is to identify the association between PAH exposure levels and contributing risk factors to derive best estimates of the effects of exposure on structural firefighters’ working environment in fire. We surveyed four databases (Embase, Medline, Scopus, and Web of Science) for this systematic literature review. Generic inverse variance method for random effects meta-analysis was applied for two exposure routes—dermal and inhalation. In dermal, the neck showed the highest dermal exposure increased after the fire activity. In inhalation, the meta-regression confirmed statistically significant increases in PAH concentrations for longer durations. We also summarized the scientific knowledge on occupational exposures to PAH in fire suppression activities. More research into uncontrolled emergency fires is needed with regard to newer chemical classes of fire smoke retardant and occupational exposure pathways. Evidence-based PAH exposure assessments are critical for determining exposure–dose relationships in large epidemiological studies of occupational risk factors.

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