scholarly journals The RANK/RANKL/OPG system in tumorigenesis and metastasis of cancer stem cell: potential targets for anticancer therapy

2017 ◽  
Vol Volume 10 ◽  
pp. 3801-3810 ◽  
Author(s):  
Mekonnen Sisay ◽  
Getnet Mengistu ◽  
Dumessa Edessa
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Anticancer Therapy ◽  
Cell Potential ◽  
Stem Cell Potential

Unravelling cancer stem cell potential

2013 ◽  
Vol 13 (10) ◽  
pp. 727-738 ◽  
Author(s):  
Benjamin Beck ◽  
Cédric Blanpain
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Potential ◽  
Stem Cell Potential

scholarly journals Bub1 is required for maintaining cancer stem cells in breast cancer cell lines

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Jeong Yoon Han ◽  
Yu Kyeong Han ◽  
Ga-Young Park ◽  
Sung Dae Kim ◽  
Chang Geun Lee
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Stem Cell ◽  
Cancer Stem Cells ◽  
Cancer Stem Cell ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Mitotic Checkpoint ◽  
Cell Potential ◽  
Stem Cell Potential

Abstract Breast cancer is a leading cause of death among women worldwide due to therapeutic resistance and cancer recurrence. Cancer stem cells are believed to be responsible for resistance and recurrence. Many efforts to overcome resistance and recurrence by regulating cancer stem cells are ongoing. Bub1 (Budding uninhibited by benzimidazoles 1) is a mitotic checkpoint serine/threonine kinase that plays an important role in chromosome segregation. Bub1 expression is correlated with a poor clinical prognosis in patients with breast cancer. We identified that depleting Bub1 using shRNAs reduces cancer stem cell potential of the MDA-MB-231 breast cancer cell line, resulting in inhibited formation of xenografts in immunocompromised mice. These results suggest that Bub1 may be associated with cancer stem cell potential and could be a target for developing anti-breast cancer stem cell therapies.

scholarly journals The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential

2015 ◽  
Vol 4 (4) ◽  
pp. 531-540 ◽  
Author(s):  
Nikola Arsic ◽  
Gilles Gadea ◽  
E. Louise Lagerqvist ◽  
Muriel Busson ◽  
Nathalie Cahuzac ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Potential ◽  
Stem Cell Potential

scholarly journals Generation and characterization of hepatocellular carcinoma cell lines with enhanced cancer stem cell potential

2018 ◽  
Vol 22 (12) ◽  
pp. 6238-6248 ◽  
Author(s):  
Julienne K. Muenzner ◽  
Philipp Kunze ◽  
Pablo Lindner ◽  
Sandra Polaschek ◽  
Kira Menke ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Cell Potential ◽  
Carcinoma Cell Lines ◽  
Hepatocellular Carcinoma Cell ◽  
Stem Cell Potential

scholarly journals Liposarcoma cells with aldefluor and CD133 activity have a cancer stem cell potential

2011 ◽  
Vol 1 (1) ◽  
Author(s):  
Eva W Stratford ◽  
Russell Castro ◽  
Anna Wennerstrøm ◽  
Ruth Holm ◽  
Else Munthe ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Potential ◽  
Stem Cell Potential

scholarly journals Canine Mesenchymal Stem Cell Potential and the Importance of Dog Breed: Implication for Cell-Based Therapies

2015 ◽  
Vol 24 (10) ◽  
pp. 1969-1980 ◽  
Author(s):  
Alessandro Bertolo ◽  
Frank Steffen ◽  
Cherry Malonzo-Marty ◽  
Jivko Stoyanov
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Potential ◽  
Dog Breed ◽  
Stem Cell Potential

P-glycoprotein expression and stem cell potential

2000 ◽  
Vol 28 (7) ◽  
pp. 68-69
Author(s):  
Fiona Spratt ◽  
Suzanne Micallef ◽  
Brenda Williams ◽  
Michele Cook ◽  
Ivan Bertoncello
Keyword(s):  
Stem Cell ◽  
Cell Potential ◽  
P Glycoprotein ◽  
Stem Cell Potential
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