scholarly journals The association of the CYP1A1 Ile462Val polymorphism with head and neck cancer risk: evidence based on a cumulative meta-analysis

2016 ◽  
pp. 2927 ◽  
Author(s):  
Yadong Wang ◽  
Haiyan Yang ◽  
Guangcai Duan ◽  
Haiyu Wang
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Evidence Based ◽  
Ile462val Polymorphism

scholarly journals Meta-Analysis of MMP2, MMP3, and MMP9 Promoter Polymorphisms and Head and Neck Cancer Risk

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e62023 ◽  
Author(s):  
Caiyun Zhang ◽  
Chao Li ◽  
Minhui Zhu ◽  
Qingzhou Zhang ◽  
Zhenghua Xie ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Promoter Polymorphisms

scholarly journals DNA Repair Gene XRCC1 Polymorphisms and Head and Neck Cancer Risk: An Updated Meta-Analysis Including 16344 Subjects

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e74059 ◽  
Author(s):  
Yin Lou ◽  
Wen-jia Peng ◽  
Dong-sheng Cao ◽  
Juan Xie ◽  
Hong-hong Li ◽  
...  
Keyword(s):  
Dna Repair ◽  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Repair Gene ◽  
Dna Repair Gene

scholarly journals miR-146a C/G polymorphism increased the risk of head and neck cancer, but overall cancer risk: an analysis of 89 studies

2018 ◽  
Vol 38 (1) ◽  
Author(s):  
Dezhong Sun ◽  
Xiaoyan Zhang ◽  
Xiaolei Zhang
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Large Scale ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Dominant Model ◽  
Case Control Studies ◽  
Stratified Analysis

Several studies have evaluated the association of miR-146a C/G with head and neck cancer (HNC) susceptibility, and overall cancer risk, but with inconclusive outcomes. To drive a more precise estimation, we carried out this meta-analysis. The literature was searched from MEDLINE (mainly PubMed), Embase, the Cochrane Library, and Google Scholar databases to identify eligible studies. A total of 89 studies were included. The results showed that miR-146a C/G was significantly associated with increased HNC risk in dominant model (I2 =15.6%, Pheterogeneity=0.282, odds ratio (OR) =1.088, 95% confidence interval (CI) =1.002–1.182, P=0.044). However, no cancer risk was detected under all genetic models. By further stratified analysis, we found that rs4919510 mutation contributed to the risk of HNC amongst Asians under homozygote model (I2 =0, Pheterogeneity=0.541, OR =1.189, 95% CI =1.025–1.378, P=0.022), and dominant model (I2 =0, Pheterogeneity=0.959, OR =1.155, 95% CI =1.016–1.312, P=0.028). Simultaneously, in the stratified analysis by source of controls, a significantly increased cancer risk amongst population-based studies was found under homozygote model, dominant model, recessive model, and allele comparison model. However, no significant association was found in the stratified analysis by ethnicity and source of control. The results indicated that miR-146a C/G polymorphism may contribute to the increased HNC susceptibility and could be a promising target to forecast cancer risk for clinical practice. However, no significant association was found in subgroup analysis by ethnicity and source of control. To further confirm these results, well-designed large-scale case–control studies are needed in the future.

scholarly journals Association between TGF-β1 Polymorphisms and Head and Neck Cancer Risk: A Meta-Analysis

2017 ◽  
Vol 8 ◽  
Author(s):  
Quan Shi ◽  
Xing Wang ◽  
Chuan Cai ◽  
Shuo Yang ◽  
Na Huo ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Tgf Β1

scholarly journals Association of the miRNA146a rs2910164 C>G Polymorphism with Head and Neck Cancer Risk: A Meta-analysis

2015 ◽  
Vol 16 (9) ◽  
pp. 3871-3874 ◽  
Author(s):  
Xiang-Jun Chen ◽  
Tao-You Zhou ◽  
Min Chen ◽  
Nian Li ◽  
Fang Liu
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis

scholarly journals Association between MMP1 -1607 1G>2G Polymorphism and Head and Neck Cancer Risk: A Meta-Analysis

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e56294 ◽  
Author(s):  
Caiyun Zhang ◽  
Xicheng Song ◽  
Minhui Zhu ◽  
Song Shi ◽  
Meng Li ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis
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