scholarly journals Population pharmacokinetics of pegaptanib sodium (Macugen®) in patients with diabetic macular edema

2015 ◽  
pp. 323
Author(s):  
Mukund Nori ◽  
Anthony Basile ◽  
Matthew Hutmacher ◽  
Ken Kowalski ◽  
Kuan Gandelman ◽  
...  
Keyword(s):  
Macular Edema ◽  
Population Pharmacokinetics ◽  
Diabetic Macular Edema ◽  
Pegaptanib Sodium

Intravitreal pegaptanib sodium (Macugen) for diabetic macular edema

2008 ◽  
Vol 86 ◽  
pp. 0-0
Author(s):  
G QUERQUES ◽  
AV BUX ◽  
D MARTINELLI ◽  
C IACULLI ◽  
N DELLE NOCI
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Pegaptanib Sodium

Lamellar macular hole following intravitreal pegaptanib sodium (Macugen) injection for diabetic macular edema

2011 ◽  
Vol 31 (6) ◽  
pp. 525-527 ◽  
Author(s):  
Giuseppe Querques ◽  
Anna V. Bux ◽  
Cristiana Iaculli ◽  
Nicola Delle Noci
Keyword(s):  
Macular Edema ◽  
Macular Hole ◽  
Diabetic Macular Edema ◽  
Lamellar Macular Hole ◽  
Pegaptanib Sodium

scholarly journals Pegaptanib Sodium versus Pegaptanib Sodium Combined with Macular Laser Photocoagulation or Laser Alone for Diabetic Macular Edema

2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
G. Querques ◽  
A. V. Bux ◽  
A. R. Fusco ◽  
C. Iaculli ◽  
N. Delle Noci
Keyword(s):  
Treatment Group ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Laser Photocoagulation ◽  
Combined Treatment ◽  
Group 13 ◽  
Pegaptanib Sodium ◽  
Corrected Visual Acuity ◽  
Group 12

Purpose. To report the outcomes after primary intravitreal pegaptanib sodium in patients with diabetic macular edema (DME).Methods. We conduced a retrospective analysis of eyes with DME treated with primary intravitreal pegaptanib sodium (Macugen) (intravitreal pegaptanib group). The results were compared with the ones of eyes treated with intravitreal pegaptanib sodium associated with macular laser photocoagulation (combined treatment group), and the ones of eyes treated with primary macular laser photocoagulation (macular laser photocoagulation group).Results. For the intravitreal pegaptanib group (13 eyes), we found significant changes in mean best-corrected visual acuity (BCVA) and reductions in mean central macular thickness (CMT) at the last follow-up visit ( and ). For the macular laser photocoagulation group (15 eyes), we found no statistically significant changes in mean BCVA and CMT at the last follow-up visit (). For the combined treatment group (12 eyes), we found no significant changes in mean BCVA at the last follow-up visit () despite significant reductions in mean CMT ().Conclusion. Intravitreal pegaptanib treatment alone may be superior to macular laser photocoagulation alone and to combined intravitreal pegaptanib treatment associated with macular laser photocoagulation in patients with DME.

A Phase 2/3, Multicenter, Randomized, Double-Masked, 2-Year Trial of Pegaptanib Sodium for the Treatment of Diabetic Macular Edema

Ophthalmology ◽  
2011 ◽  
Vol 118 (6) ◽  
pp. 1107-1118 ◽  
Author(s):  
Marla B. Sultan ◽  
Duo Zhou ◽  
Jane Loftus ◽  
Theresa Dombi ◽  
Kathleen S. Ice
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Phase 2 ◽  
Pegaptanib Sodium
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