scholarly journals Comparison of high-resolution Scheimpflug and high-frequency ultrasound biomicroscopy to anterior-segment OCT corneal thickness measurements

2013 ◽  
pp. 2239 ◽  
Author(s):  
John Kanellopoulos ◽  
George Asimellis
Keyword(s):  
High Resolution ◽  
High Frequency ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
High Frequency Ultrasound ◽  
Anterior Segment Oct ◽  
Thickness Measurements ◽  
Frequency Ultrasound

scholarly journals Imaging the Anterior Segment: High-Frequency Ultrasound and Anterior Segment OCT

2013 ◽  
Vol 2013 ◽  
pp. 1-1 ◽  
Author(s):  
Norma Allemann ◽  
D. Jackson Coleman ◽  
Charles J. Pavlin ◽  
David Huang
Keyword(s):  
High Frequency ◽  
Anterior Segment ◽  
High Frequency Ultrasound ◽  
Anterior Segment Oct ◽  
Frequency Ultrasound

High-Frequency Ultrasound Biomicroscopy versus Ultrasound and Optical Pachymetry for the Measurement of Corneal Thickness

1998 ◽  
Vol 212 (1) ◽  
pp. 1-3 ◽  
Author(s):  
Luisa Pierro ◽  
Eugenio Conforto ◽  
Antonio Giordano Resti ◽  
Rosangela Lattanzio
Keyword(s):  
High Frequency ◽  
Corneal Thickness ◽  
Ultrasound Biomicroscopy ◽  
High Frequency Ultrasound ◽  
Frequency Ultrasound

Abstract 245: Non-Invasive in vivo Assessment of the Re-Endothelialization Process Using Ultrasound Biomicroscopy in the Rat Carotid Artery Balloon Injury Model

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Samuel Röhl ◽  
Linnea Eriksson ◽  
Robert Saxelin ◽  
Mariette Lengquist ◽  
Kenneth Caidahl ◽  
...  
Keyword(s):  
Carotid Artery ◽  
High Frequency ◽  
Ultrasound Biomicroscopy ◽  
Blue Dye ◽  
High Frequency Ultrasound ◽  
Balloon Injury ◽  
En Face ◽  
In Vivo Assessment ◽  
Frequency Ultrasound

Objective: Ultrasound BioMicroscopy (UBM), or high-frequency ultrasound, is a novel technique used for assessment of anatomy and physiology small research animals. In this study, we evaluate the UBM assessment of the re-endothelialization process following denudation of the carotid artery in rats. Methods: Ultrasound BioMicroscopy data from three different experiments were analyzed. A total of 66 rats of three different strains (Sprague-Dawley, Wistar and Goto-Kakizaki) were included in this study. All animals were subjected to common carotid artery balloon injury and examined with UBM 2 and 4 weeks after injury. Re-endothelialization in UBM was measured as the length from the carotid bifurcation to the distal edge of the intimal hyperplasia. En face staining with Evans-blue dye was performed upon euthanization at 4 weeks after injury followed by tissue harvest for morphological and immunohistochemical evaluation. Results: A significant correlation (Spearman r=0.63,p<0.0001) and an agreement according to Bland-Altman test was identified when comparing all measurements of re-endothelialization in high frequency ultrasound and en face staining. Analysis by animal strain revealed a similar pattern and a significant growth in re-endothelialization length measured in UBM from 2 to 4 weeks could be identified. Immunohistochemical staining for von Willebrand factor confirmed the presence of endothelium in the areas detected as re-endothelialized by the ultrasound assessment. Conclusion: Ultrasound BioMicroscopy can be used for longitudinal in vivo assessment of the re-endothelialization following arterial injury in rats.

Intraocular Pressure–dependent Corneal Elasticity Measurement Using High-frequency Ultrasound

2019 ◽  
Vol 41 (5) ◽  
pp. 251-270 ◽  
Author(s):  
Laurentius O. Osapoetra ◽  
Dan M. Watson ◽  
Stephen A. McAleavey
Keyword(s):  
Intraocular Pressure ◽  
High Resolution ◽  
High Frequency ◽  
Wave Speed ◽  
Biomechanical Properties ◽  
Single Element ◽  
High Frequency Ultrasound ◽  
Spatially Resolved ◽  
Corneal Biomechanical Properties ◽  
Frequency Ultrasound

Measurement of corneal biomechanical properties can aid in predicting corneal responses to diseases and surgeries. For delineation of spatially resolved distribution of corneal elasticity, high-resolution elastography system is required. In this study, we demonstrate a high-resolution elastography system using high-frequency ultrasound for ex-vivo measurement of intraocular pressure (IOP)-dependent corneal wave speed. Tone bursts of 500 Hz vibrations were generated on the corneal surface using an electromagnetic shaker. A 35-MHz single-element transducer was used to track the resulting anti-symmetrical Lamb wave in the cornea. We acquired spatially resolved wave speed images of the cornea at IOPs of 7, 11, 15, 18, 22, and 29 mmHg. The IOP dependence of corneal wave speed is apparent from these images. Statistical analysis of measured wave speed as a function of IOP revealed a linear relation between wave speed and IOP cs = 0.37 + 0.22 × IOP, with the coefficient of determination R2 = 0.86. We also observed depth-dependent variations of wave speed in the cornea, decreasing from anterior toward posterior. This depth dependence is more pronounced at higher IOP values. This study demonstrates the potential of high-frequency ultrasound elastography in the characterization of spatially resolved corneal biomechanical properties.

scholarly journals Low to Very-High Frequency Ultrasound Biomicroscopy of Cell Death

2010 ◽  
Vol 16 (S2) ◽  
pp. 1110-1111
Author(s):  
GJ Czarnota
Keyword(s):  
Cell Death ◽  
High Frequency ◽  
Ultrasound Biomicroscopy ◽  
High Frequency Ultrasound ◽  
Very High Frequency ◽  
Very High ◽  
Frequency Ultrasound

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.

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