scholarly journals Intense Pulsed Plus Low-Level Light Therapy in Meibomian Gland Dysfunction

2021 ◽  
Vol Volume 15 ◽  
pp. 2803-2811
Author(s):  
Ana Marta ◽  
Pedro Manuel Baptista ◽  
João Heitor Marques ◽  
Daniel Almeida ◽  
Diana José ◽  
...  
2019 ◽  
Vol Volume 13 ◽  
pp. 993-999 ◽  
Author(s):  
Karl Stonecipher ◽  
Thomas G Abell ◽  
Bennett Chotiner ◽  
Erik Chotiner ◽  
Rick Potvin

Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 619
Author(s):  
Leonidas Solomos ◽  
Walid Bouthour ◽  
Ariane Malclès ◽  
Gabriele Thumann ◽  
Horace Massa

Background and Objectives: Evaporative dry eye disease is frequently associated with meibomian gland dysfunction. Patients are often unhappy because of daily drops, care burden, and suboptimal conventional treatments. In this study, we assessed the efficacy of a novel device, the Eye-light®, a combination of intense pulsed light therapy and low-level light therapy, as a novel treatment for meibomian gland dysfunction and dry eye disease. Materials and Methods: This was a retrospective, single-center study carried out over a 6-week period, in which 22 eyes from 11 patients were included. Each patient received four combined light therapy treatment sessions, once weekly over 4 weeks. Patients underwent a clinical examination and filled out a standardized questionnaire to evaluate symptoms one week prior to treatment, and one week after the fourth session. Results: Combined light therapy improved several ocular surface outcome measures in our patients. This study demonstrates that this adjunctive treatment significantly improves the ocular surface and quality of life of patients with dry eye disease and meibomian gland dysfunction. Conclusions: Combined light therapy may be included in meibomian gland dysfunction treatment protocols as an adjunctive rescue treatment.


2013 ◽  
Vol 39 (8) ◽  
pp. 1177-1183 ◽  
Author(s):  
Hyojin Kim ◽  
Jee Woong Choi ◽  
Jun Young Kim ◽  
Jung Won Shin ◽  
Seok-jong Lee ◽  
...  

2016 ◽  
Vol 202 (5-6) ◽  
pp. 307-318 ◽  
Author(s):  
In-Su Park ◽  
Phil-Sang Chung ◽  
Jin Chul Ahn

Human adipose-derived mesenchymal stem cells (hASCs) are an attractive cell source for tissue engineering. However, one obstacle to this approach is that the transplanted hASC population can decline rapidly in the recipient tissue. The aim of this study was to investigate the effects of low-level light therapy (LLLT) on transplanted spheroid hASCs in skin flaps of mice. hASCs were cultured in monolayers or spheroids. LLLT, hASCs, spheroids and spheroids transplanted with LLLT were applied to the skin flaps. Healing of the skin flaps was assessed by gross evaluation and by hematoxylin and eosin staining and elastin van Gieson staining. Compared with the spheroid group, skin flap healing was enhanced in the spheroid + LLLT group, including the neovascularization and regeneration of skin appendages. The survival of hASCs was enhanced by decreased apoptosis of hASCs in the skin flaps of the spheroid + LLLT group. The secretion of growth factors was stimulated in the spheroid + LLLT group compared with the ASC and spheroid groups. These data suggest that LLLT was an effective biostimulator of spheroid hASCs in the skin flaps, enhancing the survival of hASCs and stimulating the secretion of growth factors.


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