scholarly journals Corneal Thickness and Anterior Chamber Flare After Cataract Surgery: A Randomized Controlled Trial Comparing Five Regimens for Anti-Inflammatory Prophylaxis

2021 ◽  
Vol Volume 15 ◽  
pp. 2835-2845
Author(s):  
Niklas Cyril Hansen ◽  
Jesper Hoiberg Erichsen ◽  
Lars Morten Holm ◽  
Line Kessel
Keyword(s):  
Randomized Controlled Trial ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Controlled Trial ◽  
Corneal Thickness ◽  
Randomized Controlled ◽  
Anti Inflammatory ◽  
Anterior Chamber Flare

scholarly journals Randomized Controlled Trial Comparing 1-Year Outcomes of Low-Energy Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification

2021 ◽  
Vol 8 ◽  
Author(s):  
Yu-Chi Liu ◽  
Melina Setiawan ◽  
Jia Ying Chin ◽  
Benjamin Wu ◽  
Hon Shing Ong ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Patient Reported Outcomes ◽  
Controlled Trial ◽  
Low Energy ◽  
Randomized Controlled ◽  
Patient Reported ◽  
Operative Complications ◽  
Anterior Chamber Flare

Purpose: To compare 1-year clinical outcomes, phacoemulsification energy, aqueous profiles, and patient-reported outcomes of low-energy femtosecond laser-assisted cataract surgery (FLACS) vs. conventional phacoemulsification.Methods: The study is a randomized controlled trial (RCT) with paired-eye design. Eighty-five patients were randomized to receive FLACS (Ziemer LDV Z8) in one eye and conventional phacoemulsification in the fellow eye. Clinical data including phacoemulsification energy parameters (cumulative dissipated energy, phacoemulsification power, and phacoemulsification time), uncorrected and corrected distance visual acuities (UCDVA and BCDVA), manifest refraction spherical equivalent (MRSE), central corneal thickness (CCT), endothelial cell count (ECC), anterior chamber flare, and post-operative complications were obtained for 1 year. Aqueous humor was collected for the analysis of prostaglandin (PGE)2, cytokines and chemokines concentrations. Patients' reported-outcomes on surgical experiences were evaluated using an in-house questionnaire.Results: Compared to conventional phacoemulsification, the low-energy assisted FLACS group had significantly less ECC reduction at 3 months (1.5 ± 0.3% vs. 7.0 ± 2.4%; P < 0.01) and 1 year (8.2 ± 2.8% vs. 11.2 ± 3.6%; P = 0.03). There were no significant differences in the phacoemulsification energy parameters, UCDVA, BCDVA, MRSE, CCT, occurrence of post-operative complications between the 2 groups throughout post-operative 1 year. Patients' subjective surgical experiences, including the surgical duration and perceived inconvenience, were comparable between the 2 groups. FLACS resulted in significantly higher aqueous PGE2 (P < 0.01), interleukin (IL)-6 (P = 0.03), IL-8 (P = 0.03), and interferon (IFN)-γ (P = 0.04) concentrations and greater anterior chamber flare at 1 day (P = 0.02).Conclusions: Our RCT presented 1-year longitudinal clinical and laboratory data. The long-term ECC result was more favorable in low-energy FLACS. The rest of the intraoperative and post-operative outcomes, as well as patient-reported outcomes, were comparable between these two procedures.

Efficacy of topical plus intracameral anesthesia for cataract surgery in high myopia: Randomized controlled trial

2008 ◽  
Vol 34 (10) ◽  
pp. 1664-1668 ◽  
Author(s):  
Giorgio Lofoco ◽  
Francesco Ciucci ◽  
Antonio Bardocci ◽  
Pierpaolo Quercioli ◽  
Cristiano De Gaetano ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cataract Surgery ◽  
High Myopia ◽  
Controlled Trial ◽  
Randomized Controlled
Sign in / Sign up

Export Citation Format

Share Document