scholarly journals Microscope Integrated Optical Coherence Tomography Guided Descemet Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

2021 ◽  
Vol Volume 15 ◽  
pp. 3173-3181
Author(s):  
Mohamed Ibrahime Asif ◽  
Rahul Kumar Bafna ◽  
Namrata Sharma ◽  
Ananya Kaginalkar ◽  
Rajesh Sinha ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Endothelial Keratoplasty ◽  
Integrated Optical ◽  
Congenital Hereditary Endothelial Dystrophy

scholarly journals ‘Acute-angled bevel’ sign to assess donor lenticule orientation in ultra-thin descemet stripping automated endothelial keratoplasty

2019 ◽  
Vol 12 (2) ◽  
pp. e227927 ◽  
Author(s):  
Jeewan S Titiyal ◽  
Manpreet Kaur ◽  
Farin Shaikh ◽  
Aafreen Bari
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Acute Angle ◽  
Optical Coherence ◽  
Endothelial Keratoplasty ◽  
Anterior Segment Oct ◽  
Intraoperative Optical Coherence Tomography ◽  
Congenital Hereditary Endothelial Dystrophy ◽  
Graft Insertion

A 6.5-year-old boy with congenital hereditary endothelial dystrophy underwent clear corneal ultra-thin descemet stripping automated endothelial keratoplasty (DSAEK). After graft insertion, it was difficult to assess graft orientation due to hazy cornea. Intraoperative optical coherence tomography (iOCT) showed a well-attached graft and the bevelled edge of donor lenticule made an acute angle with the overlying stroma. Postoperative anterior segment OCT confirmed the presence of acute-angled bevel sign. A wetlab experiment was performed with experimental corneoscleral tissues to confirm the findings. Donor lenticule was injected in the artificial chamber with stromal-side up as well as stromal side-down. ‘Acute-angled bevel sign’ was observed on iOCT in the experimental cases with stromal-side up. In inverse graft, the acute-angled bevel was not observed, instead the configuration was obtuse angled. Identifying the ‘acute-angled bevel sign’ on iOCT confirms correct graft orientation after unfolding and is extremely useful for hazy corneas and ultrathin DSAEK lenticules.

scholarly journals Intraoperative optical coherence tomography guided corneal sweeping for removal of remnant Interface fluid during ultra-thin Descemet stripping automated endothelial keratoplasty

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Michael Mimouni ◽  
Martin Kronschläger ◽  
Manuel Ruiss ◽  
Oliver Findl
Keyword(s):  
Optical Coherence Tomography ◽  
Retrospective Study ◽  
Optical Coherence ◽  
Endothelial Keratoplasty ◽  
Intraoperative Optical Coherence Tomography ◽  
Graft Thickness

Abstract Background Remnant interface fluid following Descemet stripping automated endothelial keratoplasty (DSAEK) is associated with postoperative detachments. The aim of this study was to assess outcomes of intraoperative optical coherence tomography (iOCT) guided meticulous peripheral corneal sweeping for removal of interface fluid during ultra-thin (UT) DSAEK. Methods This retrospective study included all eyes underwent iOCT guided UT-DSAEK from October 2016 to February 2018 at the Hanusch Hospital, Vienna, Austria. Peripheral meticulous corneal sweeping was performed to remove excess fluid. Central graft thickness (CGT) was measured prior to surgery, after graft bubbling and after corneal sweeping. Remnant interface fluid rates were compared between eyes that underwent rebubbling and those that did not. Results Overall, 28 eyes of 28 patients with a mean age of 73.9 ± 10.0 years were included. An iOCT guided meticulous peripheral sweeping was performed in 89.3% (n = 25) of the cases. Following 84% (n = 21) of the peripheral sweeping performed, remnant fluid was no longer identified. Following peripheral sweeping the interface fluid height was reduced from 17.31 ± 15.96 μm to 3.46 ± 9.52 μm (p < 0.001) and CGT was reduced by 7% (p < 0.001). Rebubbling was performed in 17.9% (n = 5) of the cases. The rebubbling group had a greater proportion of patients that had remnant fluid identified with iOCT at the end of surgery despite meticulous peripheral sweeping (60.0% versus 4.4%, p = 0.01). Conclusion The iOCT identified subclinical remnant fluid in nearly 90% of UT-DSAEK cases. An iOCT guided peripheral corneal sweeping led to resolution of interface fluid in a majority of cases. Eyes with persistent remnant fluid despite peripheral corneal sweeping are more likely to require subsequent rebubbling.

Intraoperative Optical Coherence Tomography–Assisted Descemet Membrane Endothelial Keratoplasty

Cornea ◽  
2020 ◽  
Vol 39 (6) ◽  
pp. 674-679 ◽  
Author(s):  
Marc B. Muijzer ◽  
Nienke Soeters ◽  
Daniel A. Godefrooij ◽  
Chantal M. van Luijk ◽  
Robert P. L. Wisse
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Intraoperative Optical Coherence Tomography

scholarly journals Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues

2010 ◽  
Vol 70 (24) ◽  
pp. 10071-10079 ◽  
Author(s):  
Chao Zhou ◽  
David W. Cohen ◽  
Yihong Wang ◽  
Hsiang-Chieh Lee ◽  
Amy E. Mondelblatt ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Optical Coherence ◽  
Human Breast ◽  
Integrated Optical ◽  
Breast Tissues

scholarly journals Integrated Optical Coherence Tomography and Optical Coherence Microscopy Imaging of Ex Vivo Human Renal Tissues

2012 ◽  
Vol 187 (2) ◽  
pp. 691-699 ◽  
Author(s):  
Hsiang-Chieh Lee ◽  
Chao Zhou ◽  
David W. Cohen ◽  
Amy E. Mondelblatt ◽  
Yihong Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Optical Coherence ◽  
Microscopy Imaging ◽  
Optical Coherence Microscopy ◽  
Integrated Optical
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