scholarly journals Preclinical Efficacy Comparison of Cyclosporine Ophthalmic Solution 0.09% vs Cyclosporine Ophthalmic Emulsion 0.05% vs Ciclosporin Ophthalmic Emulsion 0.1% in a NOD Mouse Model of Dry Eye Disease

2020 ◽  
Vol Volume 14 ◽  
pp. 2747-2755
Author(s):  
Vinod Burade ◽  
Rishit Zalawadia ◽  
Alpesh Patel ◽  
Abayomi Ogundele
Keyword(s):  
Mouse Model ◽  
Dry Eye ◽  
Ophthalmic Solution ◽  
Dry Eye Disease ◽  
Nod Mouse ◽  
Eye Disease ◽  
Preclinical Efficacy

scholarly journals New Therapeutic Strategy and Innovative Lubricating Ophthalmic Solution in Minimizing Dry Eye Disease Associated with Cataract Surgery: A Randomized, Prospective Study

2020 ◽  
Vol 37 (4) ◽  
pp. 1664-1674 ◽  
Author(s):  
Paolo Fogagnolo ◽  
Eleonora Favuzza ◽  
Daniele Marchina ◽  
Michela Cennamo ◽  
Roberto Vignapiano ◽  
...  
Keyword(s):  
Prospective Study ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Therapeutic Strategy ◽  
Ophthalmic Solution ◽  
Dry Eye Disease ◽  
Eye Disease

scholarly journals Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease

2020 ◽  
Vol 190 (10) ◽  
pp. 2067-2079 ◽  
Author(s):  
Laura García-Posadas ◽  
Robin R. Hodges ◽  
Tor P. Utheim ◽  
Ole Kristoffer Olstad ◽  
Vanessa Delcroix ◽  
...  
Keyword(s):  
Mouse Model ◽  
Dry Eye ◽  
Lacrimal Gland ◽  
Myoepithelial Cells ◽  
Dry Eye Disease ◽  
Eye Disease

scholarly journals Effects of Cyclosporine 0.05% ophthalmic solution on diagnostic parameters of dry eye disease

2017 ◽  
Vol 5 (10) ◽  
pp. 4289
Author(s):  
Maneesha Sethi ◽  
Amarjeet Singh Bali ◽  
P. Sadhotra
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Ophthalmic Solution ◽  
Dry Eye Disease ◽  
Diagnostic Tools ◽  
Eye Disease ◽  
Inclusion Criteria ◽  
Ocular Surface Disease Index ◽  
Diagnostic Parameters ◽  
A Prospective Study

Background: Dry eye is a multifactorial disease particularly prevalent in Asia for which there are several treatments. Among anti-inflammatory treatment, cyclosporine 0.05% is preferred therapy. Our study evaluated effects of cyclosporine 0.05% ophthalmic solution on the diagnostic tools of dry eye.Material & Methods: A prospective study was carried out in ophthalmological outpatient department of ASCOMS and Hospital. Total 60 patients of dry eye disease who fulfilled the inclusion criteria were treated with cyclosporine 0.05% ophthalmic solution twice a day. The diagnostic parameters of dry eye were assessed at baseline, at month 1 and 3. Patients underwent Ocular Surface Disease Index (OSDI) score, Schirmer’s test, Tear film break up time (TBUT) .Results: After three months, mean OSDI score was significantly improved (p < 0.001). There was significant improvement in mean Schirmer score (p < 0.001). Baseline TBUT also increased significantly (p < 0.001). Conclusion: Cyclosporine 0.05% ophthalmic solution has significant effect on diagnostic parameters of dry eye disease.  

Lifitegrast Ophthalmic Solution 5%: A Review in Dry Eye Disease

Drugs ◽  
2017 ◽  
Vol 77 (2) ◽  
pp. 201-208 ◽  
Author(s):  
Gillian M. Keating
Keyword(s):  
Dry Eye ◽  
Ophthalmic Solution ◽  
Dry Eye Disease ◽  
Eye Disease
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