scholarly journals Requirement of longer term antiviral therapy in patients with cytomegalovirus anterior uveitis with corneal endothelial cell damage

2018 ◽  
Vol Volume 12 ◽  
pp. 1311-1316
Author(s):  
Yosuke Harada ◽  
Ken Fukuda ◽  
Asami Nakahira ◽  
Kentaro Tada ◽  
Tamaki Sumi ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Antiviral Therapy ◽  
Anterior Uveitis ◽  
Cell Damage ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Damage

A significant association of viral loads with corneal endothelial cell damage in cytomegalovirus anterior uveitis

2009 ◽  
Vol 94 (3) ◽  
pp. 336-340 ◽  
Author(s):  
M. Miyanaga ◽  
S. Sugita ◽  
N. Shimizu ◽  
T. Morio ◽  
K. Miyata ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Anterior Uveitis ◽  
Cell Damage ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Damage ◽  
Viral Loads

Red light has the capacity to blunt corneal endothelial cell damage in situ.

2014 ◽  
Vol 92 ◽  
pp. 0-0 ◽  
Author(s):  
C NÚÑEZ ÄLVAREZ ◽  
S OLMO-AGUADO ◽  
J MERAYO-LLOVES ◽  
NN OSBORNE
Keyword(s):  
Endothelial Cell ◽  
Cell Damage ◽  
Red Light ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Damage

scholarly journals Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0184824 ◽  
Author(s):  
Maninder Bhogal ◽  
Chan N. Lwin ◽  
Xin-Yi Seah ◽  
Elavazhagan Murugan ◽  
Khadijah Adnan ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Real Time ◽  
Cell Damage ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Damage ◽  
Time Assessment

scholarly journals Relationship between Tube Parameters and Corneal Endothelial Cell Damage after Ahmed Glaucoma Valve Implantation: A Comparative Study

2020 ◽  
Vol 9 (8) ◽  
pp. 2546
Author(s):  
Han Min Lee ◽  
Kyoung Nam Kim ◽  
Kee Sup Park ◽  
Nam Ho Lee ◽  
Sung Bok Lee ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Anterior Chamber ◽  
Cell Damage ◽  
Corneal Endothelial Cell ◽  
Tipping Point ◽  
Regression Analyses ◽  
Ahmed Glaucoma Valve ◽  
Clinical Factors ◽  
Endothelial Cell Damage ◽  
The Mean

Purpose: We compared the clinical factors, including anterior chamber tube parameters, in patients with and without corneal endothelial cell damage after Ahmed glaucoma valve (AGV) implantation. Methods: In this retrospective and comparative case series, patients who underwent AGV implantation were enrolled consecutively. Serial specular microscopy was performed before and after AGV implantation. Patients were divided into two groups depending on whether there was a significant decrease in corneal endothelial cell density (ECD), which was determined by each patient’s rate of ECD change (%/year), calculated using linear regression analyses. Tube parameters such as the tube-cornea distance (TCD) and tube-cornea angle (TCA) were measured with anterior segment optical coherence tomography. Clinical factors related to the rate of ECD change were evaluated with regression analyses and compared between the two groups. The tipping point at which tube parameters became significantly associated with the rate of ECD change was identified with broken stick regression analyses. Results: There were 30 eyes (32.3%) with ECD damage (group 1) and 63 eyes (67.7%) without damage (group 2). The mean rate of ECD change (%/year) was −18.82 ± 22.97 and 2.14 ± 2.93 in groups 1 and 2, respectively (p < 0.001). The TCA was the only clinical factor associated with the rate of ECD change (regression coefficient, β = 1.254, p < 0.001). The tipping point in the TCA was 26.70° (95% confidence interval, CI: 23.75–29.64°). The mean TCD (mm) was 0.98 ± 0.38 and 1.26 ± 0.39 (p = 0.002), and the mean TCA (degrees) was 28.67 ± 7.79 and 36.35 ± 5.35 (p < 0.001) in groups 1 and 2, respectively. Conclusions: A wider TCA was protectively associated with the rate of ECD change, and the TCA was significantly narrower in patients with ECD damage. When inserting a tube into the anterior chamber, surgeons should therefore try to secure a wide TCA of about 30°. In patients with a narrow TCA after AGV implantation, increased attention should be directed toward whether ECD decreases continuously.

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