scholarly journals Use of viscoelastic substance in ophthalmic surgery — focus on sodium hyaluronate

2008 ◽  
pp. 21 ◽  
Author(s):  
Higashide
2020 ◽  
Vol 12 (4) ◽  
pp. 51-56
Author(s):  
Igor A. Loskutov ◽  
Alina V. Korneeva ◽  
Pavel A. Lebedev

The article presents the results of an original study which was dedicated to the investigation of the new cohesive viscoelastic Cogevisc (sodium hyaluronate 1.6%) in ophthalmic surgery. Aim. Analysis of the efficacy and safety of a new cohesive viscoelastic (Cogevisc, Solopharm) in phacoemulsification. Patients and Methods. The clinical study was based on an assessment of the clinical and functional state of 80 patients (80 eyes), which were divided into 2 groups depending on viscoelastic used during the phacoemulsification procedure (Softshell technology): in group I (40 patients, 40 eyes) Viscoat was used to protect tissues, and Amvisc Plus was added to create volume; in group II (40 patients, 40 eyes) Viscoat was used to protect tissues, and Kogevisc was used to create volume. In the postoperative period, all patients received standard anti-inflammatory treatment. There was no significant difference in mean age, gender, preoperative intraocular pressure (IOP) and preoperative central corneal thickness (CCT) between the two groups. Before surgery and in the postoperative period (in one day, 7 days, and 1 month), IOP, CCT, and endothelial cell density (ECD) were measured. The duration of the procedure and the amount of the consumed fluid were estimated. Results. There was no significant difference in IOP, CCT, ECD 1 day and 1 week postoperatively between the two groups. Mean absolute refractive error was also not significantly different between the two groups. There was no significant difference in procedure duration between groups I and II (1523.81 75.66 seconds, 1500.33 92.56 seconds, respectively, p 0.001). No complications were observed during the intraocular lens implantation in both groups. Conclusion. The investigated viscoelastic Cogevisc allows creating and effectively maintaining the necessary depth of the anterior chamber and the maximum diameter of the pupil, which simplifies different stages of phacoemulsification and minimizes the risk of intraoperative complications. Promising for further research is its use in combination with an adhesive viscoelastic of the same production. Reduced cost of Cogevisc is the advantage of this viscoelastic.


1992 ◽  
Vol 18 (1) ◽  
pp. 20-26 ◽  
Author(s):  
H. Bleckmann ◽  
R. Vogt ◽  
H.-J. Garus

2004 ◽  
Vol 21 (2) ◽  
pp. 101-106
Author(s):  
D. Henzler ◽  
R. Kramer ◽  
U. H. Steinhorst ◽  
S. Piepenbrock ◽  
R. Rossaint ◽  
...  

Author(s):  
A.O. Ivanov ◽  
◽  
V.P. Fokin ◽  
L.N. Boriskina ◽  
M.A. Lopatin ◽  
...  
Keyword(s):  

Author(s):  
Sergey Bezshapochny ◽  
Andrey Loburets ◽  
Valery Loburets

Topicality: The result of surgical treatment depends largely on the chosen method of management of the postoperative period, the main purpose of which is to reduce the effects of surgical trauma. Despite the wide variety of drugs for local and systemic use, the question of pharmacotherapy of the operated sinus remains open to this day. The main properties that a modern drug should possess are safety and high clinical efficacy. Aim: to study the clinical efficacy of topical application of a complex preparation based on a saline solution containing sodium hyaluronate and dexpanthenol in patients with chronic sinusitis after functional endoscopic sinus surgery (FESS). Materials and Methods: Clinical and laboratory studies were conducted on 47 patients with chronic rhinosinusitis who underwent surgery using the FESS technique. Patients were divided into 2 groups according to the principle of the postoperative period. Patients of research group (n=21), except for traditional therapy, was used locally NASOMER (a preparation based on a water-salt solution containing sodium hyaluronate and dexpanthenol); to the control group (n=26) patients entered, in the postoperative period received traditional therapy. Traditional therapy included a toilet of the nasal cavity, the use of short-course topical decongestants, irrigation of the nasal cavity with water-salt solutions. Criteria of clinical effectiveness: data of endoscopy of the nasal cavity, rhinomanometry, activity of the mucociliary transport system. The effectiveness of functional research methods in the postoperative period was determined on the 7th and 14th day of treatment. Results: On the 3rd day of the study, an increase in the swelling of the nasal cavity was observed in patients of both clinical groups, correlated with difficulty in nasal breathing. On the 7th day, a decrease in edema was observed in patients of both groups, but in the experimental group, the index of nasal breathing, according to rhinomanometry, was significantly (p<0.05) different from the control group, and was respectively 1.54±0.14 and 2.04±0.19 kPa/l*s. On the 14th day of the study, no significant difference was observed between these indicators. When studying the activity of the ciliated epithelium of the mucous membrane of the nasal cavity, it was proved that patients of the experimental group on day 7 after surgery showed a statistically significant difference in this indicator compared to the control group (17.8±1.0 and 22.7±2.1 min. respectively). Conclusions: The use of NASOMER after surgical intervention in patients with chronic rhinosinusitis contributes to more effective treatment compared with traditional therapy, as evidenced by the rapid recovery of the main functional parameters according to active posterior rhinomanometry and mucociliary clearance. Based on the results of the studies performed, the use of NASOMER for pharmacotherapy in the postoperative period is recommended for patients who have undergone rhinosurgical interventions with the aim of reducing the period of postoperative rehabilitation as an effective anti-inflammatory and wound-healing agent.


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