scholarly journals The effects of heterogeneity on Simon Phase II clinical trial design operating characteristics

2010 ◽  
pp. 107 ◽  
Author(s):  
Christopher Barnes
Keyword(s):  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Clinical Trial Design ◽  
Phase Ii Clinical Trial ◽  
Operating Characteristics

scholarly journals A two‐stage phase II clinical trial design with nested criteria for early stopping and efficacy

2019 ◽  
Vol 18 (6) ◽  
pp. 700-713
Author(s):  
Michelle DeVeaux ◽  
Michael Kane ◽  
Wei Wei ◽  
Daniel Zelterman
Keyword(s):  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Clinical Trial Design ◽  
Phase Ii Clinical Trial ◽  
Early Stopping ◽  
Two Stage

A Bayesian-frequentist two-stage single-arm phase II clinical trial design

2012 ◽  
Vol 31 (19) ◽  
pp. 2055-2067 ◽  
Author(s):  
Gaohong Dong ◽  
Weichung Joe Shih ◽  
Dirk Moore ◽  
Hui Quan ◽  
Stephen Marcella
Keyword(s):  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Clinical Trial Design ◽  
Phase Ii Clinical Trial ◽  
Two Stage

Bayesian optimal phase II clinical trial design with time‐to‐event endpoint

2020 ◽  
Vol 19 (6) ◽  
pp. 776-786 ◽  
Author(s):  
Heng Zhou ◽  
Cong Chen ◽  
Linda Sun ◽  
Ying Yuan
Keyword(s):  
Clinical Trial ◽  
Phase Ii ◽  
Trial Design ◽  
Clinical Trial Design ◽  
Phase Ii Clinical Trial ◽  
Time To Event
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