scholarly journals A rare case of neuroleptic malignant syndrome without elevated serum creatine kinase

Author(s):  
Koichi Nisijima ◽  
Katutoshi Shioda
Author(s):  
Won Tae Bae ◽  
Jae Hui Kim ◽  
Eun Sil Park ◽  
Ji Hyun Seo ◽  
Jae Young Lim ◽  
...  

1994 ◽  
Vol 32 (5) ◽  
pp. 527-539 ◽  
Author(s):  
Christopher B. Burns ◽  
Jennifer R. Powers ◽  
Bart J. Currie

FEBS Letters ◽  
1994 ◽  
Vol 350 (2-3) ◽  
pp. 173-176 ◽  
Author(s):  
James M. Ervasti ◽  
Steven L. Roberds ◽  
Richard D. Anderson ◽  
Nicholas J.H. Sharp ◽  
Joe N. Kornegay ◽  
...  

1996 ◽  
Vol 30 (3) ◽  
pp. 248-250 ◽  
Author(s):  
Luba Ganelin ◽  
Pesach S Lichtenberg ◽  
Esther-Lee Marcus ◽  
R Gabriel Munter

OBJECTIVE: To report a case of suspected neuroleptic malignant syndrome (NMS) associated with clozapine therapy. CASE SUMMARY: A 42-year-old schizophrenic man treated with clozapine developed a temperature of 39.5 °C, diaphoresis, tachycardia, rigidity, and leukocytosis. His serum creatine kinase concentration was 25 000 U/L. A diagnosis of NMS was made. He was treated with bromocriptine and supportive therapy, and recovered within a week. DISCUSSION: Despite earlier expectations that clozapine, with a pharmacologic profile differing from that of other antipsychotic medications, might not cause NMS, NMS remains the most likely diagnosis in this case. CONCLUSIONS: NMS may be a possible complication of clozapine therapy.


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