scholarly journals Escitalopram tolerability as mono- versus augmentative therapy in patients with affective disorders: a naturalistic study

2013 ◽  
pp. 205 ◽  
Author(s):  
Bernardo Dell'Osso ◽  
Arici ◽  
Dobrea ◽  
Camuri ◽  
Benatti ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Naturalistic Study ◽  
Augmentative Therapy

P.016 Effectiveness and tolerability of vortioxetine in affective disorders: A naturalistic study

2019 ◽  
Vol 29 ◽  
pp. S31
Author(s):  
V. De Carlo ◽  
B. Grancini ◽  
M. Vismara ◽  
B. Dell'Osso
Keyword(s):  
Affective Disorders ◽  
Naturalistic Study

scholarly journals Mental health presentations to acute psychiatric services: 3-year study of prevalence and readmission risk for personality disorders compared with psychotic, affective, substance or other disorders

BJPsych Open ◽  
2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Kate L. Lewis ◽  
Mahnaz Fanaian ◽  
Beth Kotze ◽  
Brin F. S. Grenyer
Keyword(s):  
Mental Health ◽  
Personality Disorder ◽  
Personality Disorders ◽  
Affective Disorders ◽  
Psychotic Disorders ◽  
Cox Regression ◽  
Mixed Effects ◽  
Naturalistic Study ◽  
Hospital Patients ◽  
Readmission Risk

BackgroundThe relative burden and risk of readmission for people with personality disorders in hospital settings is unknown.AimsTo compare hospital use of people with personality disorder with that of people with other mental health diagnoses, such as psychoses and affective disorders.MethodNaturalistic study of hospital presentations for mental health in a large community catchment. Mixed-effects Cox regression and survival curves were generated to examine risk of readmission for each group.ResultsOf 2894 people presenting to hospital, patients with personality disorder represented 20.5% of emergency and 26.6% of in-patients. Patients with personality disorder or psychoses were 2.3 times (95% CI 1.79–2.99) more likely than others to re-present within 28 days. Personality disorder diagnosis increases rate of readmission by a factor of 8.7 (s.e. = 0.31), marginally lower than psychotic disorders (10.02, s.e. = 0.31).ConclusionsPersonality disorders place significant demands on in-patient and emergency departments, similar to that of psychoses in terms of presentation and risk of readmission.Declaration of interestNone.

scholarly journals Duloxetine in Affective Disorders: a Naturalistic Study on Psychiatric and Medical Comorbidity, Use in Association and Tolerability Across Different Age Groups

2012 ◽  
Vol 8 (1) ◽  
pp. 120-125 ◽  
Author(s):  
Bernardo Dell’Osso ◽  
Giulia Camuri ◽  
Cristina Dobrea ◽  
Massimiliano Buoli ◽  
Marta Serati ◽  
...  
Keyword(s):  
Side Effects ◽  
Affective Disorders ◽  
Chart Review ◽  
Age Groups ◽  
Retrospective Chart Review ◽  
Naturalistic Study ◽  
Medical Comorbidity ◽  
Duration Of Treatment ◽  
Gastrointestinal Problems ◽  
Norepinephrine Reuptake Inhibitor

Objective:Duloxetine, a selective serotonin and norepinephrine reuptake inhibitor (SNRI), is currently approved in many countries for the treatment of Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD). The present naturalistic study was aimed to investigate tolerability of Duloxetine in a sample of patients with affective disorders and psychiatric/medical comorbidity, comparing tolerability in monotherapy versus polytherapy and across different age groups.Methods:The sample included 165 patients, affected by anxiety and/or mood disorders with or without comorbidity, who had been taken Duloxetine for at least 1 month. Sample variables were collected through a retrospective chart review.Results:Most common primary diagnoses were MDD (49.1 %), Bipolar Disorder (BD) (15.7 %) and GAD (5.5%). The 40 % of the sample had psychiatric comorbidity: in particular, anxiety disorders (15.8 %) (GAD 7.9%, Panic Disorder –PD- 7.3%) and personality disorders (9.1%) as the most frequent ones. With respect to medical comorbidities (68% of the sample), hypertension (12.1%) and diabetes (7.3%) were the most common ones. Mean duration of treatment and dosage of Duloxetine were, respectively, 11 months (± 9.1) and 70 mg/day (± 28.6). The 68 % of the sample received Duloxetine in association with other drugs. Minor side-effects, in particular drowsiness and gastrointestinal problems, were reported by 15 % of the sample. No difference in terms of tolerability across distinct groups, divided on the basis of mono- vs polytherapy as well as of different age, was found.Conclusion:Duloxetine, mostly administered in patients with affective disorders with psychiatric/ medical comorbidity and in association with other drugs, appeared to be well tolerated, showing limited rates of side effects of mild intensity. Further naturalistic studies are warranted to confirm present results.

Inhibition of Rat Brain Monoamine Oxidase Activities by Psoralen and Isopsoralen: Implications for the Treatment of Affective Disorders

2001 ◽  
Vol 88 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Ling Dong Kong ◽  
Ren Xiang Tan ◽  
Anthony Yiu Ho Woo ◽  
Christopher Hon Ki Cheng2Note
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Affective Disorders ◽  
Brain Monoamine

Letters of reference: A naturalistic study of the effects of confidentiality.

1984 ◽  
Vol 39 (1) ◽  
pp. 29-31 ◽  
Author(s):  
Stephen J. Ceci ◽  
Douglas Peters
Keyword(s):  
Naturalistic Study
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