scholarly journals Real-World Treatment Patterns and Adherence to Oral Medication Among Patients with Bipolar Disorders: A Retrospective, Observational Study Using a Healthcare Claims Database

2021 ◽  
Vol Volume 17 ◽  
pp. 821-833
Author(s):  
Takeshi Inoue ◽  
Hiromi Sano ◽  
Yoshitsugu Kojima ◽  
Sakiko Yamada ◽  
Osamu Shirakawa
Keyword(s):  
Observational Study ◽  
Real World ◽  
Bipolar Disorders ◽  
Treatment Patterns ◽  
Oral Medication ◽  
Retrospective Observational Study ◽  
Claims Database

Understanding the Users with Chronic Pain on AI CBT Mental Health App (Wysa): A Mixed-Methods Retrospective Observational Study (Preprint)

2021 ◽  
Author(s):  
S Meheli ◽  
Chaitali Sinha ◽  
Madhura Kabada
Keyword(s):  
Mental Health ◽  
Chronic Pain ◽  
Pain Management ◽  
Observational Study ◽  
Real World ◽  
Effect Size ◽  
Retrospective Observational Study ◽  
Medium Effect ◽  
Health Concerns ◽  
Perceived Needs

BACKGROUND Digital health interventions can bridge barriers in access to treatment of care for individuals with chronic pain. OBJECTIVE This study aimed to evaluate the perceived needs, engagement and the effectiveness of the mental health app Wysa on mental health outcomes among real-world users who reported chronic pain and engaged with the app for support. METHODS Real-world data from users (N = 2,194) who reported chronic pain and associated health conditions in their conversations with a mental health app was analyzed using a mixed-method retrospective observational study. An inductive thematic analysis was used to analyse conversational data of users with chronic pain to assess perceived needs, along with comparative macro-analyses of conversational flows to capture engagement within the app. Additionally, the scores from a subset of users who completed a set of pre-post assessment questionnaires, namely PHQ-9 (N=69) and GAD-7 (N=57), were examined to evaluate the effectiveness of Wysa in providing support for mental health concerns for those managing chronic pain. RESULTS The themes emerging from the conversations of users with chronic pain included Health Concerns, Socioeconomic Concerns, and Pain Management Concerns. Findings from the quantitative analysis indicated that users with chronic pain showed significantly greater app engagement (p value <2.2e-16) than users without chronic pain, with a large effect size (Vargha and Delaney’s A- 0.76 -0.8). Furthermore, the sample of users with pre-post assessments during the study period were found to have significant improvements in group means on both PHQ-9 and GAD-7 symptom scores, with medium effect size (Cohens’d, 0.6-0.61), respectively. CONCLUSIONS The findings indicate that users look for tools that can help them address their concerns related to mental health, pain management, and sleep issues. The study findings also indicate the breadth of needs for users with chronic pain and the lack of support structures, and suggests that Wysa can provide effective support to bridge the gap.

scholarly journals Real-world use of procalcitonin and other biomarkers among sepsis hospitalizations in the United States: A retrospective, observational study

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205924 ◽  
Author(s):  
Eric Gluck ◽  
H. Bryant Nguyen ◽  
Kishore Yalamanchili ◽  
Margaret McCusker ◽  
Jaya Madala ◽  
...  
Keyword(s):  
United States ◽  
Observational Study ◽  
Real World ◽  
The United States ◽  
Retrospective Observational Study

Real-World Treatment Patterns for Lung Neuroendocrine Tumors: A Claims Database Analysis

Oncology ◽  
2018 ◽  
Vol 94 (5) ◽  
pp. 281-288 ◽  
Author(s):  
Michael S. Broder ◽  
Beilei Cai ◽  
Eunice Chang ◽  
Maureen P. Neary ◽  
Elya Papoyan ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Real World ◽  
Treatment Patterns ◽  
Database Analysis ◽  
Claims Database

scholarly journals Real-World Observational Study on the Characteristics and Treatment Patterns of Allergic Asthma Patients Receiving Omalizumab in Canada

2020 ◽  
Vol Volume 14 ◽  
pp. 725-735
Author(s):  
Jason K Lee ◽  
Suvina Amin ◽  
Michelle Erdmann ◽  
Atif Kukaswadia ◽  
Jelena Ivanovic ◽  
...  
Keyword(s):  
Observational Study ◽  
Allergic Asthma ◽  
Real World ◽  
Treatment Patterns ◽  
Asthma Patients

Treatment Choices and Patterns in Migraine Patients With and Without a Cardiovascular Risk Profile

Cephalalgia ◽  
2009 ◽  
Vol 29 (3) ◽  
pp. 322-330 ◽  
Author(s):  
EA Wames-van der Heijden ◽  
CC Tijssen ◽  
ACG Egberts
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Observational Study ◽  
Cardiovascular Risk Factors ◽  
Risk Profile ◽  
Treatment Patterns ◽  
Retrospective Observational Study ◽  
Cardiovascular Risk Profile ◽  
Treatment Choices ◽  
Antimigraine Drugs

Treatment patterns in migraine patients with cardiovascular risk factors are largely unknown. A retrospective observational study was conducted to characterize the baseline cardiovascular risk profile of new users of specific abortive migraine drugs, and to investigate treatment choices and patterns in patients with and without a known cardiovascular risk profile. New users of a triptan, ergotamine or Migrafin® ( n = 36 839) from 1 January 1990 to 31 December 2006 were included. Approximately 90 of all new users did not have a clinically recognized cardiovascular risk profile. The percentage of new users with a cardiovascular risk profile did not differ between new users of a triptan, ergotamine or Migrafin® and also did not change during the study period of 17 years. Differences in treatment choices and patterns between migraine patients with and without a known cardiovascular risk profile reveal a certain reticence in prescribing vasoconstrictive antimigraine drugs to patients at cardiovascular risk.

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