scholarly journals Interrelation Between Increased BDNF Gene Methylation and High Sociotropy, a Personality Vulnerability Factor in Cognitive Model of Depression

2020 ◽  
Vol Volume 16 ◽  
pp. 1257-1263
Author(s):  
Toshinori Shirata ◽  
Akihito Suzuki ◽  
Yoshihiko Matsumoto ◽  
Keisuke Noto ◽  
Kaoru Goto ◽  
...  
Keyword(s):  
Cognitive Model ◽  
Bdnf Gene ◽  
Gene Methylation ◽  
Vulnerability Factor ◽  
Personality Vulnerability

Long-term ovariectomy increases BDNF gene methylation status in mouse hippocampus

2014 ◽  
Vol 144 ◽  
pp. 243-252 ◽  
Author(s):  
Guillermo S. Moreno-Piovano ◽  
Jorgelina Varayoud ◽  
Enrique H. Luque ◽  
Jorge G. Ramos
Keyword(s):  
Methylation Status ◽  
Bdnf Gene ◽  
Gene Methylation ◽  
Mouse Hippocampus

Studies on relativity of p73 gene methylation and non-Hodgkin lymphoma

2010 ◽  
Vol 34 (8) ◽  
pp. S48-S48
Author(s):  
Jing‑Hong Pei ◽  
Sai‑Qun Luo ◽  
Jiang‑Hua Chen ◽  
Hua‑Wu Xiao ◽  
Wei‑Xin Hu
Keyword(s):  
Hodgkin Lymphoma ◽  
Gene Methylation ◽  
Non Hodgkin Lymphoma ◽  
P73 Gene

Why Can’t I Stop Thinking About It?

2015 ◽  
Vol 74 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Monique C. Pfaltz ◽  
Beatrice Mörstedt ◽  
Andrea H. Meyer ◽  
Frank H. Wilhelm ◽  
Joe Kossowsky ◽  
...  
Keyword(s):  
Thought Suppression ◽  
Positive Association ◽  
Repetitive Behaviors ◽  
Thought Processes ◽  
Obsessive Compulsive ◽  
Vulnerability Factor ◽  
Compulsive Disorder ◽  
Order Factor ◽  
Maladaptive Thought ◽  
Severe Anxiety

Obsessive-compulsive disorder (OCD) is a severe anxiety disorder characterized by frequent obsessive thoughts and repetitive behaviors. Neuroticism is a vulnerability factor for OCD, yet the mechanisms by which this general vulnerability factor affects the development of OCD-related symptoms are unknown. The present study assessed a hierarchical model of the development of obsessive thoughts that includes neuroticism as a general, higher-order factor, and specific, potentially maladaptive thought processes (thought suppression, worry, and brooding) as second-order factors manifesting in the tendency toward obsessing. A total of 238 participants completed questionnaires assessing the examined constructs. The results of mediator analyses demonstrated the hypothesized relationships: A positive association between neuroticism and obsessing was mediated by thought suppression, worry, and brooding. Independent of the participant’s sex, all three mediators contributed equally and substantially to the association between neuroticism and obsessing. These findings extend earlier research on hierarchical models of anxiety and provide a basis for further refinement of models of the development of obsessive thoughts.

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