scholarly journals Differential Diagnosis Of Multiple-System Atrophy With Parkinson’s Disease By External Anal- And Urethral-Sphincter Electromyography

2019 ◽  
Vol Volume 15 ◽  
pp. 3061-3067 ◽  
Author(s):  
Feng Qiu ◽  
Kunyu Wang ◽  
Tingting Li ◽  
Dandan Song ◽  
Zhiwei Wang ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169405 ◽  
Author(s):  
Tatsuya Yamamoto ◽  
Masato Asahina ◽  
Yoshitaka Yamanaka ◽  
Tomoyuki Uchiyama ◽  
Shigeki Hirano ◽  
...  

Author(s):  
Doug Everett Hobson

The most common disorder in a patient presenting to a movement disorder clinic will be parkinsonism. The challenge is to provide the patient with the most accurate diagnosis and prognosis possible. The assumption at the time of initial presentation of the clinical diagnosis of Parkinson's disease is often wrong (20-25%). Waiting to see the pattern of progression, and response to medication provides invaluable additional information. This manuscript summarizes the clinical manifestations of Parkinson's disease and the main akinetic-rigid syndromes (progressive supranuclear palsy, multiple system atrophy, cortical-basal ganglionic degeneration, and dementia with Lewy bodies) that make up the differential diagnosis.


2009 ◽  
Vol 67 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Luiz Felipe Rocha Vasconcellos ◽  
Sergio A. Pereira Novis ◽  
Denise Madeira Moreira ◽  
Ana Lucia Z. Rosso ◽  
Ana Claudia C.B. Leite

The differential diagnosis of Parkinsonism based on clinical features, sometimes may be difficult. Diagnostic tests in these cases might be useful, especially magnetic resonance imaging, a noninvasive exam, not as expensive as positron emission tomography, and provides a good basis for anatomical analysis. The magnetic resonance spectroscopy analyzes cerebral metabolism, yielding inconsistent results in parkinsonian disorders. We selected 40 individuals for magnetic resonance imaging and spectroscopy analysis, 12 with Parkinson's disease, 11 with progressive supranuclear palsy, 7 with multiple system atrophy (parkinsonian type), and 10 individuals without any psychiatric or neurological disorders (controls). Clinical scales included Hoenh and Yahr, unified Parkinson's disease rating scale and mini mental status examination. The results showed that patients with Parkinson's disease and controls presented the same aspects on neuroimaging, with few or absence of abnormalities, and supranuclear progressive palsy and multiple system atrophy showed abnormalities, some of which statistically significant. Thus, magnetic resonance imaging and spectroscopy could be useful as a tool in differential diagnosis of Parkinsonism.


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