scholarly journals PAC1 receptor (ADCYAP1R1) genotype and problematic alcohol use in a sample of young women

2017 ◽  
Vol Volume 13 ◽  
pp. 1483-1489 ◽  
Author(s):  
Wojciech Dragan ◽  
Piotr Czerski ◽  
Małgorzata Dragan
Keyword(s):  
Alcohol Use ◽  
Young Women ◽  
Pac1 Receptor ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use

A Developmental Perspective on the Genetic Basis of Alcohol Use Disorder

2018 ◽  
Author(s):  
Elisa M. Trucco ◽  
Gabriel L. Schlomer ◽  
Brian M. Hicks
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Developmental Perspective ◽  
Relative Contribution ◽  
Intermediate Phenotypes ◽  
Problematic Alcohol ◽  
Age Related ◽  
Genetic And Environmental Factors ◽  
Problematic Alcohol Use

Approximately 48–66% of the variation in alcohol use disorders is heritable. This chapter provides an overview of the genetic influences that contribute to alcohol use disorder within a developmental perspective. Namely, risk for problematic alcohol use is framed as a function of age-related changes in the relative contribution of genetic and environmental factors and an end state of developmental processes. This chapter discusses the role of development in the association between genes and the environment on risk for alcohol use disorder. Designs used to identify genetic factors relevant to problematic alcohol use are discussed. Studies examining developmental pathways to alcohol use disorder with a focus on endophenotypes and intermediate phenotypes are reviewed. Finally, areas for further investigation are offered.

Longitudinal predictors of problematic alcohol use in adolescence: A 2-year follow-up study

2021 ◽  
pp. 106952
Author(s):  
Lutz Wartberg ◽  
Gloria Fischer-Waldschmidt ◽  
Levente Kriston ◽  
Christina W. Hoven ◽  
Marco Sarchiapone ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Follow Up Study ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use

Problematic alcohol use and marital distress: An interdependence theory perspective

2013 ◽  
Vol 22 (4) ◽  
pp. 294-312 ◽  
Author(s):  
Lindsey M. Rodriguez ◽  
Clayton Neighbors ◽  
C. Raymond Knee
Keyword(s):  
Alcohol Use ◽  
Marital Distress ◽  
Problematic Alcohol ◽  
Interdependence Theory ◽  
Problematic Alcohol Use

Utilization of Mental Health Services and Risk of 12-month Problematic Alcohol Use

2007 ◽  
Vol 31 (4) ◽  
pp. 392-401 ◽  
Author(s):  
Galle Encrenaz ◽  
Viviane Kovess-Masfty ◽  
David Sapinho ◽  
Christine Chan Chee ◽  
Antoine Messiah
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Mental Health Services ◽  
Health Services ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use

scholarly journals Problematic alcohol use and reduced hippocampal volume: a meta-analytic review

2017 ◽  
Vol 47 (13) ◽  
pp. 2288-2301 ◽  
Author(s):  
S. Wilson ◽  
J. L. Bair ◽  
K. M. Thomas ◽  
W. G. Iacono
Keyword(s):  
Alcohol Use ◽  
Meta Analysis ◽  
Hippocampal Volume ◽  
Future Research ◽  
Cross Sectional ◽  
Problematic Alcohol ◽  
Analytic Review ◽  
Males And Females ◽  
Clinically Significant ◽  
Problematic Alcohol Use

BackgroundA number of studies reports reduced hippocampal volume in individuals who engage in problematic alcohol use. However, the magnitude of the difference in hippocampal volume between individuals with v. without problematic alcohol use has varied widely, and there have been null findings. Moreover, the studies comprise diverse alcohol use constructs and samples, including clinically significant alcohol use disorders and subclinical but problematic alcohol use (e.g. binge drinking), adults and adolescents, and males and females.MethodsWe conducted the first quantitative synthesis of the published empirical research on associations between problematic alcohol use and hippocampal volume. In total, 23 studies were identified and selected for inclusion in the meta-analysis; effects sizes were aggregated using a random-effects model.ResultsProblematic alcohol use was associated with significantly smaller hippocampal volume (d = −0.53). Moderator analyses indicated that effects were stronger for clinically significant v. subclinical alcohol use and among adults relative to adolescents; effects did not differ among males and females.ConclusionsProblematic alcohol use is associated with reduced hippocampal volume. The moderate overall effect size suggests the need for larger samples than are typically included in studies of alcohol use and hippocampal volume. Because the existing literature is almost entirely cross-sectional, future research using causally informative study designs is needed to determine whether this association reflects premorbid risk for the development of problematic alcohol use and/or whether alcohol has a neurotoxic effect on the hippocampus.

scholarly journals Examining the Attitudes of Non-Psychiatric Practicing Healthcare Workers Towards Patients With Alcohol Problems in General Hospital Setting

2022 ◽  
Vol 16 ◽  
pp. 117822182110657
Author(s):  
Ho Teck Tan ◽  
Yit Shiang Lui ◽  
Lai Huat Peh ◽  
Rasaiah Munidasa Winslow ◽  
Song Guo
Keyword(s):  
Alcohol Use ◽  
Hospital Setting ◽  
Well Being ◽  
Alcohol Problems ◽  
Alcohol Intervention ◽  
Screening And Brief Intervention ◽  
Daily Work ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use ◽  
Doctors And Nurses

Background and objectives: Problematic alcohol-use affect the physical and mental well-being of hospitalised individuals and may receive screening and brief-intervention during treatment. Non-psychiatric doctors and nurses might respond inadequately due to negative attitudes and beliefs. This study aimed to examine these attitudes of non-psychiatric workers in the medical and surgical wards. Methods: A total of 457 doctors and 1643 nurses were recruited from the medical, surgical and orthopaedic disciplines over a period of 4 months. Three questionnaires were administered: demographics, Alcohol & Alcohol-Problems Perceptions Questionnaire (AAPPQ) and Staff Perception of Alcohol Treatment Resources. Results: About 128 doctors and 785 nurses responded. Around 75.5% doctors and 51.9% nurses endorsed role-legitimacy in the AAPPQ. Both the doctor (86.7%) and nurse (77.6%) groups agreed on the importance to initiate intervention for patients with problematic alcohol-use in daily work. Both groups were sceptical and negative towards these patients endorsing low-level role-adequacy (41.2%), role-support (36.9%), motivation (36.5%), task-specific self-esteem (25.1) as well as work satisfaction (20.5%). Conclusion/discussion: Doctors and nurses demonstrated low levels of therapeutic commitments towards patients with problematic alcohol-use thereby necessitating the introduction of in-house programmes to educate, empower and emphasise the importance of therapeutic contact with patients for alcohol intervention. Scientific significance: The prompt identification and treatment of patients with alcohol problems are contingent on the workers’ attitudes towards them. This study’s results should spark a nation-wide interest to improve the training and recognition of such patients and providing adequate educational resources.

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