scholarly journals Determinants of Undernutrition Among Adult People on Antiretroviral Therapy in Goba Hospital, Southeast Ethiopia: A Case–Control Study

2020 ◽  
Vol Volume 12 ◽  
pp. 223-236
Author(s):  
Falaho Sani Kalil ◽  
Teshome Kabeta ◽  
Habtemu Jarso ◽  
Mohammed Hasen ◽  
Jemal Ahmed ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Case Control Study ◽  
Case Control ◽  
Southeast Ethiopia ◽  
Control Study

scholarly journals Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy

2017 ◽  
Vol 218 (2) ◽  
pp. 239-248 ◽  
Author(s):  
Konstantia Angelidou ◽  
Peter W Hunt ◽  
Alan L Landay ◽  
Cara C Wilson ◽  
Benigno Rodriguez ◽  
...  
Keyword(s):  
T Cell ◽  
Antiretroviral Therapy ◽  
T Cell Activation ◽  
Cell Activation ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Determinant factors for the occurrence of tuberculosis after initiation of antiretroviral treatment among adult patients living with HIV at Dessie Referral Hospital, South Wollo, Northeast Ethiopia, 2020. A case-control study

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248490
Author(s):  
Mehd Abdu ◽  
Yeshimebet Ali ◽  
Samuel Anteneh ◽  
Mohammed Yesuf ◽  
Adane Birhanu ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Opportunistic Infection ◽  
Study Design ◽  
Random Sampling ◽  
Case Control Study ◽  
Case Control ◽  
Referral Hospital ◽  
Living With Hiv ◽  
Dessie Referral Hospital ◽  
Control Study

Introduction Globally, tuberculosis takes the first rank for the ill-health of people living with HIV/AIDS. Despite the favorable outcome of antiretroviral therapy, the risk of tuberculosis remains higher among HIV patients. This obliges to identify factors for its occurrence and further prevention of drug-resistant tuberculosis. There is a contradiction between different studies and studies conducted in Ethiopia studied poorly the association between adherence to antiretroviral therapy and viral load with tuberculosis. Studies conducted in the study area were limited to cross-sectional study design. Therefore, this study claimed to identify factors determining the occurrence of tuberculosis after initiation of antiretroviral therapy. Methods This study was conducted at Dessie Referral Hospital by using a case-control study design on a sample of 565 with a control: case ratio of 3:1. Participants from controls were selected by systematic random sampling and from cases by consecutive random sampling. The data were collected by interviewing through structured questionnaires and from the medical record. The data were entered into Epi data version 3.1. In the multivariable analysis, variables with a P-value of ≤0.05 were anticipated as independent determinant factors. Result Patients without separate kitchen (AOR: 3.547, 95% CI: 2.137, 5.888), having opportunistic infection (AOR: 3.728, 95% CI: 2.058, 6.753), CD4 count of <350 cells/mm3 (AOR: 3.383, 95% CI: 1.520, 7.528), baseline WHO stage III (AOR: 3.321, 95% CI: 1.688, 6.534) or IV (AOR: 2.900, 95% CI: 1.251, 6.722), don’t taking IPT (AOR: 3.701, 95% CI: 2.228, 6.147) and those who were poorly adherent (AOR: 2.626, 95% CI: 1.272, 5.423) or moderately adherent (AOR: 3.455, 95% CI: 1.885, 6.335) to anti-retroviral therapy were more likely to develop tuberculosis after anti-retroviral therapy initiation. Conclusion Poor housing conditions, having an opportunistic infection, low CD4 count, starting ART at the advanced HIV stage, don’t take IPT, and being poorly adherent to antiretroviral therapy were associated with the occurrence of TB after initiation of ART. The institution should screen for TB as early as possible and strictly follow their drug adherence.

scholarly journals Determinants of Anemia Among Pregnant Women Attending Antenatal Care in Bale-Robe Town Health Facilities, Bale zone, Southeast Ethiopia: A Case-Control Study

2021 ◽  
Author(s):  
Mohammed Hasen Badeso ◽  
Falaho Sani Kalili ◽  
Mohammed Seid Abdulle
Keyword(s):  
Antenatal Care ◽  
Dietary Intake ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Health Facilities ◽  
Menstrual Bleeding ◽  
Second Trimester ◽  
Southeast Ethiopia ◽  
Control Study

Abstract IntroductionIn Ethiopia, the prevalence of anemia in pregnant women differs geographically and ranged from 15.8–56.8%. The objective of this study is to identify the determinants of anemia among pregnant women attending antenatal care in health facilities of Bale-Robe Town, Southeast Ethiopia.MethodsA facility-based case-control study was conducted in Bale-Robe hospital and Baha-biftu health center in Bale-Robe, Southeast Ethiopia. A total of 282 pregnant women participated in the study (141 cases and 141 controls). Cases were pregnant women with altitude-adjusted hemoglobin value < 11.0 g/dl at the first and third trimesters, and < 10.5 g/dl at the second trimester. Controls were pregnant women with hemoglobin value ≥ 11.0 g/dl at first and third trimesters and ≥ 10.5 g/dl at the second trimester. A structured and pretested questionnaire was used to collect data. A multivariable logistic regression analysis was applied to assess the determinants of anemia. Determinants were categorized as sociodemographic and economic, obstetric and medical, and dietary intake and behavioral.ResultsHousewife occupation (AOR=2.1, 95% CI=1.12-3.92), prolonged menstrual bleeding (AOR=2.33, 95% CI=1.38-3.92) and undernutrition (AOR=4.03, 95% CI=1.38-11.83) were factors significantly associated with anemia in pregnant women.ConclusionHousewife occupation, prolonged menstrual bleeding, and malnutrition were the determinants of anemia in pregnant women. Hence, anemia prevention and control strategy in pregnant women should include adequate dietary intake, and strengthening nutritional counseling for pregnant women during antenatal care is also required by the health care provider.

scholarly journals Determinants of virological failure among adults on first-line highly active antiretroviral therapy at public health facilities in Kombolcha town, Northeast, Ethiopia: a case–control study

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e036223
Author(s):  
Habtamu Mengist Meshesha ◽  
Zelalem Mehari Nigussie ◽  
Anemaw Asrat ◽  
Kebadnew Mulatu
Keyword(s):  
Public Health ◽  
Antiretroviral Therapy ◽  
Virological Failure ◽  
Highly Active Antiretroviral Therapy ◽  
Case Control Study ◽  
Case Control ◽  
First Line ◽  
Highly Active ◽  
Northeast Ethiopia ◽  
Control Study

ObjectiveTo identify determinants of virological failure among HIV-infected adults on first-line highly active antiretroviral therapy at public health facilities in Kombolcha town, Northeast, Ethiopia, in 2019.MethodsAn unmatched case–control study was conducted from April to May 2019. About 130 cases and 259 controls were selected by simple random sampling. Data were extracted from charts of patients using a structured checklist. Multiple logistic regression analysis was performed to identify possible factors. Hosmer-Lemeshow goodness of fit test was used to check the model. Finally, independent predictor variables of virological failure were identified based on adjusted OR (AOR) with 95% CI and a p value of 0.05.ResultsThe odds of virological failure were 2.4-fold (AOR=2.44, 95% CI 1.353 to 4.411) higher in clients aged <35 years compared with older clients, fivefold (AOR=5.00, 95% CI 2.60 to 9.63) higher in clients who did not disclose their HIV status, threefold (AOR=2.99, 95% CI 1.33 to 6.73) higher in clients with poor adherence, and 7.5-fold (AOR=7.51, 95% CI 3.98 to 14.14) higher in clients who had recent CD4 count of ≤250 cells/mm3.Conclusion and recommendationThis study revealed that age, marital status, occupation, disclosure status, baseline functional status, missed clinic visit, current antiretroviral therapy regimen, adherence to treatment and recent CD4 count were significantly associated with virological failure. Therefore, adherence support should be strengthened among clients. Missed clinic visits should also be reduced, as it could help clients better adhere to treatment, and therefore boost their immunity and suppress viral replication.

Risk Factors in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Patients Undergoing Antiretroviral Therapy in the State of Pernambuco, Brazil: A Case–Control Study

2010 ◽  
Vol 8 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Thais Gelenske ◽  
Francisco Alfredo Bandeira e Farias ◽  
Ricardo Arraes de Alencar Ximenes ◽  
Heloísa Ramos Lacerda de Melo ◽  
Maria de Fátima Pessoa Militão de Albuquerque ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Acquired Immunodeficiency Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Control Study

Relationship Between Polymerase Gamma (POLG) Polymorphisms and Antiretroviral Therapy-Induced Lipodystrophy in HIV-1 Infected Patients: A Case-Control Study

2009 ◽  
Vol 7 (2) ◽  
pp. 244-253 ◽  
Author(s):  
Franck Chiappini ◽  
Elina Teicher ◽  
Raphael Saffroy ◽  
Brigitte Debuire ◽  
Daniel Vittecoq ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Case Control Study ◽  
Case Control ◽  
Polymerase Gamma ◽  
Hiv 1 ◽  
Control Study
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