scholarly journals Effects of deep brain stimulation amplitude on motor performance in Parkinson’s disease

2012 ◽  
pp. 73 ◽  
Author(s):  
Alison Conovaloff ◽  
Krishnamurthi ◽  
Mahant ◽  
Samanta ◽  
Abbas
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Motor Performance ◽  
Stimulation Amplitude ◽  
Deep Brain

scholarly journals Deep brain stimulation amplitude alters posture shift velocity in Parkinson’s disease

2012 ◽  
Vol 6 (4) ◽  
pp. 325-332 ◽  
Author(s):  
Narayanan Krishnamurthi ◽  
Stefani Mulligan ◽  
Padma Mahant ◽  
Johan Samanta ◽  
James J. Abbas
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Shift Velocity ◽  
Stimulation Amplitude ◽  
Deep Brain

scholarly journals Effect of subthalamic nucleus deep brain stimulation on dual-task cognitive and motor performance in isolated dystonia

2014 ◽  
Vol 86 (4) ◽  
pp. 404-409 ◽  
Author(s):  
Kelly A Mills ◽  
Leslie C Markun ◽  
Marta San Luciano ◽  
Rami Rizk ◽  
I Elaine Allen ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Subthalamic Nucleus ◽  
Brain Stimulation ◽  
Dual Task ◽  
Motor Performance ◽  
Deep Brain

Linear and nonlinear increases of rCBF associated with variations of deep brain stimulation amplitude

NeuroImage ◽  
2001 ◽  
Vol 13 (6) ◽  
pp. 1182
Author(s):  
Bernhard Haslinger ◽  
Henning Boecker ◽  
Christian Büchel ◽  
Jan Vesper ◽  
Peter Bartenstein ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Linear And Nonlinear ◽  
Stimulation Amplitude ◽  
Deep Brain

scholarly journals Investigation of Magnetoelectric Sensor Requirements for Deep Brain Stimulation Electrode Localization and Rotational Orientation Detection

Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2527
Author(s):  
Mevlüt Yalaz ◽  
Günther Deuschl ◽  
Markus Butz ◽  
Alfons Schnitzler ◽  
Ann-Kristin Helmers ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Quantum Interference ◽  
Pulse Width ◽  
Limit Of Detection ◽  
Critical Role ◽  
Digital Signal ◽  
Measurement Duration ◽  
Stimulation Amplitude ◽  
Deep Brain

Correct position and orientation of a directional deep brain stimulation (DBS) electrode in the patient’s brain must be known to fully exploit its benefit in guiding stimulation programming. Magnetoelectric (ME) sensors can play a critical role here. The aim of this study was to determine the minimum required limit of detection (LOD) of a ME sensor that can be used for this application by measuring the magnetic field induced by DBS. For this experiment, a commercial DBS system was integrated into a head phantom and placed inside of a state-of-the-art Superconducting Quantum Interference Device (SQUID)-based magnetoencephalography system. Measurements were performed and analyzed with digital signal processing. Investigations have shown that the minimum required detection limit depends on various factors such as: measurement distance to electrode, bandwidth of magnetic sensor, stimulation amplitude, stimulation pulse width, and measurement duration. For a sensor that detects only a single DBS frequency (stimulation frequency or its harmonics), a LOD of at least 0.04 pT/Hz0.5 is required for 3 mA stimulation amplitude and 60 μμs pulse width. This LOD value increases by an order of magnitude to 0.4 pT/Hz0.5 for a 1 kHz, and by approximately two orders to 3 pT/Hz0.5 for a 10 kHz sensor bandwidth. By averaging, the LOD can be reduced by at least another 2 orders of magnitude with a measurement duration of a few minutes.

Nicht-medikamentöse Optionen zur Behandlung pharmakoresistenter Epilepsien

2018 ◽  
Vol 75 (7) ◽  
pp. 448-454
Author(s):  
Thomas Grunwald ◽  
Judith Kröll
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Tiefe Hirnstimulation ◽  
Ketogene Diät ◽  
Deep Brain

Zusammenfassung. Wenn mit den ersten beiden anfallspräventiven Medikamenten keine Anfallsfreiheit erzielt werden konnte, so ist die Wahrscheinlichkeit, dies mit anderen Medikamenten zu erreichen, nur noch ca. 10 %. Es sollte dann geprüft werden, warum eine Pharmakoresistenz besteht und ob ein epilepsiechirurgischer Eingriff zur Anfallsfreiheit führen kann. Ist eine solche Operation nicht möglich, so können palliative Verfahren wie die Vagus-Nerv-Stimulation (VNS) und die tiefe Hirnstimulation (Deep Brain Stimulation) in eine bessere Anfallskontrolle ermöglichen. Insbesondere bei schweren kindlichen Epilepsien stellt auch die ketogene Diät eine zu erwägende Option dar.

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