scholarly journals Age-related and sex-related changes in perfusion index in response to noxious electrical stimulation in healthy subjects

2014 ◽  
pp. 91 ◽  
Author(s):  
Nakae ◽  
Toshiki Nishimura ◽  
Masahiko Shibata ◽  
Takashi Mashimo ◽  
Yuji Fujino
Keyword(s):  
Electrical Stimulation ◽  
Healthy Subjects ◽  
Perfusion Index ◽  
Age Related

scholarly journals Physical activity in elderly

2015 ◽  
Vol 25 (4) ◽  
pp. 249 ◽  
Author(s):  
Jan Cvecka ◽  
Veronika Tirpakova ◽  
Milan Sedliak ◽  
Helmut Kern ◽  
Winfried Mayr ◽  
...  
Keyword(s):  
Physical Activity ◽  
Electrical Stimulation ◽  
Muscle Mass ◽  
Irreversible Process ◽  
Significant Decline ◽  
Positive Effects ◽  
Age Related ◽  
And Performance ◽  
And Function ◽  
Age Related Changes

Aging is a multifactorial irreversible process associated with significant decline in muscle mass and neuromuscular functions. One of the most efficient methods to counteract age-related changes in muscle mass and function is physical exercise. An alternative effective intervention to improve muscle structure and performance is electrical stimulation. In the present work we present the positive effects of physical activity in elderly and a study where the effects of a 8-week period of functional electrical stimulation and strength training with proprioceptive stimulation in elderly are compared.

Acupuncture and Sensory Thresholds

1989 ◽  
Vol 17 (03n04) ◽  
pp. 99-110 ◽  
Author(s):  
T. Lundeberg ◽  
S. Eriksson ◽  
S. Lundeberg ◽  
M. Thomas
Keyword(s):  
Electrical Stimulation ◽  
Plasma Levels ◽  
Healthy Subjects ◽  
Pain Threshold ◽  
Sensory Thresholds ◽  
Threshold Values ◽  
Threshold Elevation ◽  
Beta Endorphin ◽  
Manual Stimulation

The effect of acupuncture on sensory thresholds was studied in 6 healthy subjects. The modes of acupuncture studied were: 1. manual stimulation, 2. electrical stimulation at 2 Hz, 3. electrical stimulation at 80 Hz. Superfiscial-acupuncture was used as placebo. Insertions of needles or application of electrodes were bilateral, at St 7 (intrasegmental) or Li 4 (extrasegmental). The study showed that manual or electro-acupuncture were effective when used intrasegmentally, raising pain threshold values 1.1 to 1.4 times that prior to stimulation. The pain threshold elevation obtained was not significantly related to plasma levels of beta-endorphin, ACTH or prolactin. Other sensory threholds, thermal, vibrotactile and electrotactile were unaffected by such conditioned sitmulation. Superfiscial-acupuncture had no significant effect on the sensory thresholds tested.

Age-Related Changes in the Renin-Aldosterone System in Healthy Subjects

2011 ◽  
pp. P2-619-P2-619
Author(s):  
Rene Baudrand ◽  
Carmen Campino ◽  
Marlene Aglony ◽  
Alejandro Martinez-Aguayo ◽  
Cristian A Carvajal ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Age Related ◽  
Age Related Changes

Effects of magnetic stimulation compared to electrical stimulation on muscle contraction in quadriceps femoris muscle of healthy subjects: A pilot study

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Ryosuke Nakanishi ◽  
◽  
Minoru Tanaka ◽  
Noriaki Maeshige ◽  
Hidemi Fujino ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Muscle Contraction ◽  
Healthy Subjects ◽  
Magnetic Stimulation ◽  
Muscle Thickness ◽  
Rectus Femoris ◽  
Superficial Layer ◽  
Quadriceps Femoris ◽  
Quadriceps Femoris Muscle ◽  
Femoris Muscle

Background/Aims: This study investigated whether pulsed magnetic stimulation contracts superficial and/or deep muscles compared with those induced by electrical stimulations, i.e., low- and kilohertzfrequency currents. Methods: Eight healthy subjects were recruited and measured the quadriceps femoris muscle thickness using ultrasound imaging, and Visual Analog Scale (VAS) for stimulation-induced pain during the same stimulation intensity. Results: Pulsed magnetic stimulation increased the thickness of rectus femoris muscle similar to other electrical stimulations, but not the vastus intermedius muscle. Meanwhile, the pain score of VAS caused by pulsed magnetic stimulation was lower than that by those electrical stimulations. Conclusions: These results suggest that pulsed magnetic stimulation is effective for the contraction of superficial layer muscles without stimulation-induced pain but not for contraction of deep layer muscles. Keywords: pulsed magnetic stimulation; electrical stimulation; stimulation-induced pain; muscle contraction.

Age-related changes in colonic function in rats

1984 ◽  
Vol 247 (5) ◽  
pp. G542-G546 ◽  
Author(s):  
J. N. McDougal ◽  
M. S. Miller ◽  
T. F. Burks ◽  
D. L. Kreulen
Keyword(s):  
Electrical Stimulation ◽  
Age Groups ◽  
Circular Muscle ◽  
Colonic Transit ◽  
Maximum Response ◽  
Suitable Model ◽  
Fischer 344 ◽  
Age Related ◽  
Muscle Histology

Aging in humans is associated with changes in gastrointestinal function. We wanted to determine whether a similar phenomenon occurs in rats and whether rats would be a suitable model to study changes in the gastrointestinal tract with age. Intestinal transit, response in vitro of circular colon strips to bethanechol and electrical stimulation, and colonic smooth muscle histology were compared for post-pubertal (5-12 mo) and senescent (25-28 mo) male Fischer 344 rats. Colonic transit of 51Cr was decreased 45% in senescent rats in comparison with younger rats. The maximum response of circularly oriented muscle strips from senescent rats to electrical stimulation of nerves was 32% less than the maximum response of strips from postpubertal rats. Likewise, the maximum response of the muscle strips to bethanechol was 16% less in the senescent group compared with the postpubertal group. There was no difference between the two groups in the EC50 of bethanechol. The thickness of the muscle layers and the percent circular muscle of strips fixed at optimum length were the same in both age groups. The senescent rat appears to be a useful model for the study of gastrointestinal changes with aging.

Opposite modulations of corticospinal excitability by intermittent and continuous peripheral electrical stimulation in healthy subjects

2021 ◽  
Vol 740 ◽  
pp. 135467
Author(s):  
Kiyoshige Ishibashi ◽  
Daisuke Ishii ◽  
Satoshi Yamamoto ◽  
Akira Noguchi ◽  
Kenya Tanamachi ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Healthy Subjects ◽  
Corticospinal Excitability ◽  
Peripheral Electrical Stimulation

scholarly journals Exploring Epigenetic Age in Response to Intensive Relaxing Training: A Pilot Study to Slow Down Biological Age

2019 ◽  
Vol 16 (17) ◽  
pp. 3074 ◽  
Author(s):  
Pavanello ◽  
Campisi ◽  
Tona ◽  
Lin ◽  
Iliceto
Keyword(s):  
Myocardial Infarction ◽  
Age Estimation ◽  
Healthy Subjects ◽  
Molecular Mechanisms ◽  
Biological Age ◽  
Chronological Age ◽  
Biological Aging ◽  
Epigenetic Clock ◽  
Age Related ◽  
Epigenetic Age

DNA methylation (DNAm) is an emerging estimator of biological aging, i.e., the often-defined “epigenetic clock”, with a unique accuracy for chronological age estimation (DNAmAge). In this pilot longitudinal study, we examine the hypothesis that intensive relaxing training of 60 days in patients after myocardial infarction and in healthy subjects may influence leucocyte DNAmAge by turning back the epigenetic clock. Moreover, we compare DNAmAge with another mechanism of biological age, leucocyte telomere length (LTL) and telomerase. DNAmAge is reduced after training in healthy subjects (p = 0.053), but not in patients. LTL is preserved after intervention in healthy subjects, while it continues to decrease in patients (p = 0.051). The conventional negative correlation between LTL and chronological age becomes positive after training in both patients (p < 0.01) and healthy subjects (p < 0.05). In our subjects, DNAmAge is not associated with LTL. Our findings would suggest that intensive relaxing practices influence different aging molecular mechanisms, i.e., DNAmAge and LTL, with a rejuvenating effect. Our study reveals that DNAmAge may represent an accurate tool to measure the effectiveness of lifestyle-based interventions in the prevention of age-related diseases.

Haemodynamic changes with the use of neuromuscular electrical stimulation compared to intermittent pneumatic compression

2014 ◽  
Vol 30 (5) ◽  
pp. 365-372 ◽  
Author(s):  
KJ Williams ◽  
HM Moore ◽  
AH Davies
Keyword(s):  
Electrical Stimulation ◽  
Healthy Subjects ◽  
Peak Velocity ◽  
Neuromuscular Electrical Stimulation ◽  
Haemodynamic Effect ◽  
Maximum Velocity ◽  
Intermittent Pneumatic Compression ◽  
Laser Doppler ◽  
Thrombosis Prophylaxis ◽  
Electrical Stimulator

Introduction Enhancement of peripheral circulation has been shown to be of benefit in many vascular disorders, and the clinical effectiveness of intermittent pneumatic compression is well established in peripheral vascular disease. This study compares the haemodynamic efficacy of a novel neuromuscular electrical stimulation device with intermittent pneumatic compression in healthy subjects. Methods Ten healthy volunteers (mean age 27.1 ± 3.8 years, body mass index 24.8 ± 3.6 kg/m2) were randomised into two groups, in an interventional crossover trial. Devices used were the SCD Express™ Compression System, (Covidien, Ireland) and the geko™, (Firstkind Ltd, UK). Devices were applied bilaterally, and haemodynamic measurements taken from the left leg. Changes to haemodynamic parameters (superficial femory artery and femoral vein) and laser Doppler measurements from the hand and foot were compared. Results Intermittent pneumatic compression caused 51% ( p = 0.002), 5% (ns) and 3% (ns) median increases in venous peak velocity, time-averaged maximum velocity and volume flow, respectively; neuromuscular electrical stimulator stimulation caused a 103%, 101% and 101% median increases in the same parameters (all p = 0.002). The benefit was lost upon deactivation. Intermittent pneumatic compression did not improve arterial haemodynamics. Neuromuscular electrical stimulator caused 11%, 84% and 75% increase in arterial parameters ( p < 0.01). Laser Doppler readings taken from the leg were increased by neuromuscular electrical stimulator ( p < 0.001), dropping after deactivation. For intermittent pneumatic compression, the readings decreased during use but increased after cessation. Hand flux signal dropped during activation of both devices, rising after cessation. Discussion The neuromuscular electrical stimulator device used in this study enhances venous flow and peak velocity in the legs of healthy subjects and is equal or superior to intermittent pneumatic compression. This warrants further clinical and economic evaluation for deep venous thrombosis prophylaxis and exploration of the haemodynamic effect in venous pathology. It also enhances arterial time-averaged maximum velocity and flow rate, which may prove to be of clinical use in the management of peripheral arterial disease. The effect on the microcirculation as evidenced by laser Doppler fluximetry may reflect a clinically beneficial target in microvascular disease, such as in the diabetic foot.

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